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Role of Spectrin in Endocytosis

open access: yesCells, 2022
Cytoskeletal spectrin is found in (non)erythroid cells. Eukaryotic endocytosis takes place for internalizing cargos from extracellular milieu. The role of spectrin in endocytosis still remains poorly understood.
Donghai Li
doaj   +3 more sources

Shigella flexneri utilize the spectrin cytoskeleton during invasion and comet tail generation [PDF]

open access: yesBMC Microbiology, 2012
Background The spectrin cytoskeleton is emerging as an important host cell target of enteric bacterial pathogens. Recent studies have identified a crucial role for spectrin and its associated proteins during key pathogenic processes of Listeria ...
Ruetz Tyson J   +2 more
doaj   +4 more sources

Calmodulin binding to human spectrin [PDF]

open access: bronzeFEBS Letters, 1984
Calmodulin is shown to interact with human spectrin dimer. The binding was highly calcium‐dependent and observed in two different kinds of experiments. Firstly, affinity chromatography of calmodulin on a Sepharose 4B column with immobilized spectrin, and secondly, partition in aqueous two‐phase polymer systems.
Åsa M. M. Berglund   +2 more
openalex   +4 more sources

Calpain in Traumatic Brain Injury: From Cinderella to Central Player [PDF]

open access: yesCells
Traumatic Brain Injury (TBI) is a major global health concern and a leading cause of death and disability, especially in young adults. It triggers complex secondary injury cascades, e.g., calcium dysregulation, mitochondrial dysfunction and protease ...
Carla Schallerer   +3 more
doaj   +2 more sources

Mechanical behavior of actin and spectrin subjected to high strain rate: A molecular dynamics simulation study

open access: yesComputational and Structural Biotechnology Journal, 2021
Recent nanoscopy and super-resolution microscopy studies have substantiated the structural contribution of periodic actin-spectrin lattice to the axonal cytoskeleton of neuron.
Md Ishak Khan   +2 more
doaj   +1 more source

Muscle spectrin. [PDF]

open access: yesJ Physiol
Rasband MN, Hoke A, Zhang C, Sert O.
europepmc   +2 more sources

Competition between myosin II and βH-spectrin regulates cytoskeletal tension

open access: yeseLife, 2023
Spectrins are membrane cytoskeletal proteins generally thought to function as heterotetramers comprising two α-spectrins and two β-spectrins. They influence cell shape and Hippo signaling, but the mechanism by which they influence Hippo signaling has ...
Consuelo Ibar   +3 more
doaj   +1 more source

Commentary: SPTBN5, encoding the βV-spectrin protein, leads to a syndrome of intellectual disability, developmental delay, and seizures [PDF]

open access: goldFrontiers in Molecular Neuroscience, 2022
Liedewei Van De Vondel   +7 more
doaj   +2 more sources

Glycosylation of erythrocyte spectrin and its modification in visceral leishmaniasis. [PDF]

open access: yesPLoS ONE, 2011
Using a lectin, Achatinin-H, having preferential specificity for glycoproteins with terminal 9-O-acetyl sialic acid derivatives linked in α2-6 linkages to subterminal N-acetylgalactosamine, eight distinct disease-associated 9-O-acetylated ...
Sajal Samanta   +10 more
doaj   +1 more source

Age-dependent ataxia and neurodegeneration caused by an αII spectrin mutation with impaired regulation of its calpain sensitivity

open access: yesScientific Reports, 2021
The neuronal membrane-associated periodic spectrin skeleton (MPS) contributes to neuronal development, remodeling, and organization. Post-translational modifications impinge on spectrin, the major component of the MPS, but their role remains poorly ...
Arkadiusz Miazek   +8 more
doaj   +1 more source

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