Results 91 to 100 of about 42,373 (249)
The Flavivirus NS3 Protein: Its Multifaceted Roles and Therapeutic Potential
Abstract Mosquito‐borne flaviviruses are important human pathogenic viruses and can cause an array of symptoms ranging from asymptomatic to mild illness but can progress to severe disease conditions. Prominent members of the family Flaviviridae include Dengue virus, Zika virus, and West Nile virus, whose spread has increased globally due to the ...
Haejeong Lee, Hee Cho, Michaela U. Gack
wiley +1 more source
Isoforms of Spectrin and Ankyrin Reflect the Functional Topography of the Mouse Kidney. [PDF]
The kidney displays specialized regions devoted to filtration, selective reabsorption, and electrolyte and metabolite trafficking. The polarized membrane pumps, channels, and transporters responsible for these functions have been exhaustively studied ...
Michael C Stankewich +4 more
doaj +1 more source
Interaction of rat liver lysosomal membranes with actin. [PDF]
Membranes were prepared from lysosomes purified 80-fold by centrifugation in a discontinuous metrizamide gradient. When salt-washed membranes were combined with rabbit muscle actin, an increase in viscosity could be measured using a falling ball ...
Bame, KJ, Mehrabian, M, Rome, LH
core
Cytoskeleton influence on normal and tangent fluctuation modes in the red blood cells
We argue that the paradoxal softness of the red blood cells (RBC) in fluctuation spectra experiments is apparent. We show that the effective surface shear modulus $\mu_s$ of the RBC obtained from fluctuation data and that measured in static deformation ...
Lorman, V. L., Rochal, S. B.
core +3 more sources
Axon Initial Segment: Structure, Biological Functions, Diseases, and Therapeutic Targets
The axon initial segment (AIS) is a specialized axonal domain critical for maintaining neuronal polarity, action potential initiation, and network stability. This review summarizes the necessary elements for maintaining AIS structure and plasticity, discussing crucial biological functions of AIS in neuronal signaling and the neural circuit homeostasis,
Dong‐Yan Song +4 more
wiley +1 more source
Force balance and membrane shedding at the Red Blood Cell surface
During the aging of the red-blood cell, or under conditions of extreme echinocytosis, membrane is shed from the cell plasma membrane in the form of nano-vesicles.
D. E. Discher +13 more
core +1 more source
ATP effects on response of human erythrocyte membrane to high pressure
Phosphorylation of membrane proteins in human erythrocytes is mediated by intracellular ATP levels. Such phosphorylation modulates the interactions of the bilayer with the cytoskeleton and affects the membrane stability under high pressure.
Takeo Yamaguchi, Shunji Fukuzaki
doaj +1 more source
Several isoforms of spectrin membrane skeleton proteins have been localized to the Golgi complex. Golgi-specific membrane skeleton proteins associate with the Golgi as a detergent-resistant cytoskeletal structure that likely undergoes a dynamic assembly process that accommodates Golgi membrane dynamics.
openaire +2 more sources
Deletion within the Src homology domain 3 of Bruton's tyrosine kinase resulting in X-linked agammaglobulinemia (XLA). [PDF]
The gene responsible for X-linked agammaglobulinemia (XLA) has been recently identified to code for a cytoplasmic tyrosine kinase (Bruton's agammaglobulinemia tyrosine kinase, BTK), required for normal B cell development. BTK, like many other cytoplasmic
Chen, SH +11 more
core +1 more source
Directional intracellular cargo transport is traditionally attributed to motor stepping along stationary microtubule (MT) tracks. We propose a complementary mechanism of cargo co‐migration with moving MTs. This mode requires cargo–MT tethering and directed MT motion.
Chuying Zhou, Mineko Kengaku
wiley +1 more source

