Role of Spectrin in Endocytosis
Cells, 2022 Cytoskeletal spectrin is found in (non)erythroid cells. Eukaryotic endocytosis takes place for internalizing cargos from extracellular milieu. The role of spectrin in endocytosis still remains poorly understood.
Donghai Li
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Calpain in Traumatic Brain Injury: From Cinderella to Central Player [PDF]
CellsTraumatic Brain Injury (TBI) is a major global health concern and a leading cause of death and disability, especially in young adults. It triggers complex secondary injury cascades, e.g., calcium dysregulation, mitochondrial dysfunction and protease ...
Carla Schallerer +3 more
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Dynamic spectrin/ankyrin-G microdomains promote lateral membrane assembly by opposing endocytosis [PDF]
Science Advances, 2015 Locally dynamic micrometer-scale domains based on spectrin and ankyrin-G determine membrane identity by preventing endocytosis. Current physical models for plasma membranes emphasize dynamic 10- to 300-nm compartments at thermodynamic equilibrium but ...
Paul M. Jenkins, Meng He, Vann Bennett
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Commentary: SPTBN5, encoding the βV-spectrin protein, leads to a syndrome of intellectual disability, developmental delay, and seizures [PDF]
Frontiers in Molecular Neuroscience, 2022 Liedewei Van De Vondel +7 more
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Structural organization of the actin-spectrin–based membrane skeleton in dendrites and soma of neurons [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2017 Boran Han +3 more
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Characterization of Spectrin Family Genes and Their Evolutionary Roles in Domestication and Breeding of the Silkworm <i>Bombyx mori</i>. [PDF]
InsectsLu K +9 more
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Computational and Structural Biotechnology Journal, 2021 Recent nanoscopy and super-resolution microscopy studies have substantiated the structural contribution of periodic actin-spectrin lattice to the axonal cytoskeleton of neuron.
Md Ishak Khan +2 more
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The spectrin cytoskeleton integrates endothelial mechanoresponses
Nature Cell Biology, 2022 Physiological blood flow induces the secretion of vasoactive compounds, notably nitric oxide, and promotes endothelial cell elongation and reorientation parallel to the direction of applied shear.
S. Mylvaganam +7 more
semanticscholar +1 more source
βII spectrin (SPTBN1): biological function and clinical potential in cancer and other diseases
International Journal on Biological Sciences, 2021 βII spectrin, the most common isoform of non-erythrocyte spectrin, is a cytoskeleton protein present in all nucleated cells. Interestingly, βII spectrin is essential for the development of various organs such as nerve, epithelium, inner ear, liver and ...
Panyu Yang +10 more
semanticscholar +1 more source
Calmodulin binding to human spectrin [PDF]
FEBS Letters, 1984 Calmodulin is shown to interact with human spectrin dimer. The binding was highly calcium‐dependent and observed in two different kinds of experiments. Firstly, affinity chromatography of calmodulin on a Sepharose 4B column with immobilized spectrin, and secondly, partition in aqueous two‐phase polymer systems.
Åsa M. M. Berglund +2 more
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