Posttranslational control of membrane-skeleton (ankyrin and alpha beta- spectrin) assembly in early myogenesis [PDF]
, 1985 Adult chicken skeletal muscle cells express polypeptides that are antigenically related to alpha-spectrin (Mr 240,000) and beta-spectrin (Mr 220,000-225,000), the major components of the erythrocyte membrane- skeleton, and to ankyrin (Mr 237,000; also ...
Lazarides, Elias, Nelson, W. James
core +1 more source
Avian lens spectrin: subunit composition compared with erythrocyte and brain spectrin [PDF]
, 1983 Chicken lens spectrin is composed predominantly of equimolar amounts of two polypeptides with solubility properties similar, but not identical, to erythrocyte spectrin.
Granger, Bruce L. +2 more
core +1 more source
Long noncoding RNA regulation of spermatogenesis via the spectrin cytoskeleton in Drosophila
G3: Genes, Genomes, Genetics, 2021 The spectrin cytoskeleton has been shown to be critical in diverse processes such as axon development and degeneration, myoblast fusion, and spermatogenesis.
Mark J Bouska, Hua Bai
doaj +1 more source
Tissue-specific Expression of Distinct Spectrin and Ankyrin Transcripts in Erythroid and Nonerythroid Cells [PDF]
, 1985 cDNA probes for three components of the erythroid membrane skeleton, α spectrin, β spectrin, and ankyrin, were obtained by using monospecific antibodies to screen a λgt11 expression vector library containing cDNA prepared from chicken erythroid poly(A)^+
Lazarides, Elias +3 more
core +3 more sources
The Physiological Molecular Shape of Spectrin: A Compact Supercoil Resembling a Chinese Finger Trap. [PDF]
PLoS Computational Biology, 2015 The primary, secondary, and tertiary structures of spectrin are reasonably well defined, but the structural basis for the known dramatic molecular shape change, whereby the molecular length can increase three-fold, is not understood.
Jeffrey W Brown +5 more
doaj +1 more source
Glial βii spectrin contributes to paranode formation and maintenance [PDF]
, 2018 Action potential conduction along myelinated axons depends on high densities of voltage-gated Na channels at the nodes of Ranvier. Flanking each node, paranodal junctions (paranodes) are formed between axons and Schwann cells in the peripheral nervous ...
Benusa, Savannah D. +12 more
core +1 more source
Control of erythroid differentiation: asynchronous expression of the anion transporter and the peripheral components of the membrane skeleton in AEV- and S13-transformed cells [PDF]
, 1986 Chicken erythroblasts transformed with avian erythroblastosis virus or S13 virus provide suitable model systems with which to analyze the maturation of immature erythroblasts into erythrocytes.
Boyer, Brigitte +3 more
core +1 more source
Molecular consequences of SCA5 mutations in the spectrin-repeat domains of β-III-spectrin. [PDF]
J Biol ChemDenha SA +7 more
europepmc +3 more sources
Erythroid and nonerythroid spectrins [PDF]
Blood, 1993 Abstract Recent developments have contributed important information to understanding the role of spectrins in the RBC membrane skeleton and nonerythroid cells. Many questions can now be framed, informed by structural knowledge of various spectrin subunit types and alternatively spliced variants, that previously could not have been ...
J C, Winkelmann, B G, Forget
openaire +3 more sources
Brazilian Journal of Medical and Biological Research, 2002 Hereditary spherocytosis (HS) is a common inherited anemia characterized by the presence of spherocytic red cells. Defects in several membrane protein genes have been involved in the pathogenesis of HS. ß-Spectrin-related HS seems to be common. We report
D.S. Bassères +3 more
doaj +1 more source