Results 1 to 10 of about 520,314 (375)

Spatially-resolved in vivo plant metabolomics by laser ablation-based mass spectrometry imaging (MSI) techniques: LDI-MSI and LAESI [PDF]

open access: yesFrontiers in Plant Science, 2015
This short review aims to summarize the current developments and applications of mass spectrometry-based methods for in situ profiling and imaging of plants with minimal or no sample pre-treatment or manipulation.
Aleš eSvatoš, Benjamin eBartels
doaj   +4 more sources

Electrospray Ionization Mass Spectrometry: A Technique to Access the Information beyond the Molecular Weight of the Analyte [PDF]

open access: yesInternational Journal of Analytical Chemistry, 2012
The Electrospray Ionization (ESI) is a soft ionization technique extensively used for production of gas phase ions (without fragmentation) of thermally labile large supramolecules.
Shibdas Banerjee, Shyamalava Mazumdar
doaj   +4 more sources

Advances in MALDI Mass Spectrometry Imaging Single Cell and Tissues

open access: yesFrontiers in Chemistry, 2022
Compared with conventional optical microscopy techniques, mass spectrometry imaging (MSI) or imaging mass spectrometry (IMS) is a powerful, label-free analytical technique, which can sensitively and simultaneously detect, quantify, and map hundreds of ...
Xiaoping Zhu   +6 more
doaj   +2 more sources

Analysis of inositol phosphate metabolism by capillary electrophoresis electrospray ionization mass spectrometry

open access: yesNature Communications, 2020
Myo-Inositol phosphates (InsPs) and pyrophosphates (PP-InsPs) are important second messengers but their analysis remains challenging. Here, the authors develop a capillary electrophoresis-mass spectrometry method for the identification and quantitation ...
Danye Qiu   +14 more
doaj   +2 more sources

Applications of Tandem Mass Spectrometry (MS/MS) in Protein Analysis for Biomedical Research

open access: yesMolecules, 2022
Mass Spectrometry (MS) allows the analysis of proteins and peptides through a variety of methods, such as Electrospray Ionization-Mass Spectrometry (ESI-MS) or Matrix-Assisted Laser Desorption Ionization-Mass Spectrometry (MALDI-MS).
Anca-Narcisa Neagu   +5 more
doaj   +2 more sources

Electrospray ionization mass spectrometry fingerprinting of propolis [PDF]

open access: yesThe Analyst, 2004
Crude ethanolic extracts of propolis, a natural resin, have been directly analysed using electrospray ionization mass (ESI-MS) and tandem mass spectrometry (ESI-MS/MS) in the negative ion mode. European, North American and African samples have been analyzed, but emphasis has been given to Brazilian propolis which displays diverse and region-dependent ...
Vassya Bankova   +6 more
openaire   +5 more sources

Analysis of Oligonucleotides by Electrospray Ionization Mass Spectrometry [PDF]

open access: yesCurrent Protocols in Nucleic Acid Chemistry, 2000
AbstractBecause of the high molecular weights and thermal lability of biomolecules such as nucleic acids and protein, they can be difficult to analyze by mass spectrometry. Such analyses require a “soft” ionization method that is capable of generating intact molecular ions.
Polo, Lenore M., Limbach, Patrick A.
openaire   +5 more sources

Recent Applications of Ambient Ionization Mass Spectrometry for Environmental Pollutant Detection [PDF]

open access: yesZhipu Xuebao, 2023
Along with the industrial development and human society progress, large number of pollutants have been discharged to induce the environmental pollution, which have attracted global attentions.
QIN Jing-yi, OUYANG Jin, NA Na
doaj   +1 more source

Extractive electrospray ionization mass spectrometry for analytical evaluation and synthetic preparation of pharmaceutical chemicals

open access: yesFrontiers in Pharmacology, 2023
Extraction electrospray ionization mass spectrometry (EESI-MS), due to the unique configuration of its ionization module, enables the effective ionization of trace molecules of interest in samples containing complex matrices with high sensitivity, high ...
Manman Qin   +9 more
doaj   +1 more source

Enhancing Metabolomic Coverage in Positive Ionization Mode Using Dicationic Reagents by Infrared Matrix-Assisted Laser Desorption Electrospray Ionization

open access: yesMetabolites, 2021
Mass spectrometry imaging is a powerful tool to analyze a large number of metabolites with their spatial coordinates collected throughout the sample. However, the significant differences in ionization efficiency pose a big challenge to metabolomic mass ...
Ying Xi, David C. Muddiman
doaj   +1 more source

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