Results 61 to 70 of about 7,487,886 (340)
Behavioral, computational, and neuroimaging studies of acquired apraxia of speech [PDF]
, 2014 A critical examination of speech motor control depends on an in-depth understanding of network connectivity associated with Brodmann areas 44 and 45 and surrounding cortices.
Ballard, Kirrie J. +2 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Regional White Matter Damage Predicts Speech Fluency in Chronic Post-Stroke Aphasia
Frontiers in Human Neuroscience, 2014 Recently, two different white matter regions that support speech fluency have been identified: the aslant tract and the anterior segment of the arcuate fasciculus (ASAF).
Alexandra eBasilakos +5 more
doaj +1 more source
Frontiers in Neurology, 2023 IntroductionApraxia of speech (AOS) is a motor speech disorder impairing the coordination of complex articulatory movements needed to produce speech.
Alexis L. Pracar +4 more
doaj +1 more source
Von Kempelen et al. : remarks on the history of articulatory-acoustic modelling [PDF]
, 2005 The contribution of von Kempelen’s “Mechanism of Speech” to the ‘phonetic sciences‘ will be analyzed with respect to his theoretical reasoning on speech and speech production on the one hand and on the other in connection with his practical insights ...
Pompino-Marschall, Bernd
core
Abnormal Speech Motor Control in Individuals with 16p11.2 Deletions. [PDF]
, 2018 Speech and motor deficits are highly prevalent (>70%) in individuals with the 600 kb BP4-BP5 16p11.2 deletion; however, the mechanisms that drive these deficits are unclear, limiting our ability to target interventions and advance treatment.
Demopoulos, Carly +8 more
core +3 more sources
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Computer-Implemented Articulatory Models for Speech Production: A Review
Frontiers in Robotics and AI, 2022 Modeling speech production and speech articulation is still an evolving research topic. Some current core questions are: What is the underlying (neural) organization for controlling speech articulation?
Bernd J. Kröger
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source