Results 121 to 130 of about 19,776 (295)

Microbiome and aging: Trajectories of microbiome age across human ecosystems and their systemic effects

iMeta, EarlyView.
Microbiome age (MA) has emerged as an innovative biomarker of biological aging, reflecting host aging trajectories through dynamic alterations in microbial composition, function, and host–microbe interactions across multiple body ecosystems. Diverse computational strategies—including traditional machine learning, deep learning, and multi‐omics ...
Zhexin Ni, Jiaojiao Xie, Zhichun Zhang, Keming Zhang, Jie Ding, Mingyang Chang, Ying Su, Yunan Zhang, Mingfei Yao, Chengyuan Wang, Yan Yan, Wenjie Fang, Hainv Gao, Xuecong Tian, Yangshuo Li, Xinlin Zhu, Wen Zhang, Wanqing Liao, Gaoyuan Xu, Guojing Chen, Xiaoyi Lv, Chaoqin Yu, Weihua Pan, Vadim Molodtsov, Lanjuan Li, Yue Gao, Wei Zhou   +26 more
wiley   +1 more source

Paternal Exposure to the Neonicotinoid Pesticide Clothianidin Alters Sperm MicroRNA Profiles in Mice and Intergenerationally Reduces Locomotor Activity in Male Offspring

Journal of Applied Toxicology, EarlyView.
ABSTRACT Accumulating evidence suggests that paternal environmental factors have epigenetic effects on sperm and influence offspring. Neonicotinoid pesticides (NNs), which are widely used around the world, are known to affect offspring phenotypes through maternal exposure in mice, but the effect of the paternal exposure remains unknown.
Makiko Ito, Tetsushi Hirano, Sarika Nunobiki, Ayano Yoshimoto, Yukako Hara, Yuya Ishida, Sakura Yonoichi, Youhei Mantani, Toshifumi Yokoyama, Yoshiaki Tabuchi, Yoshinori Ikenaka, Nobuhiko Hoshi   +11 more
wiley   +1 more source

Sperm DNA fragmentation testing—clinical utility [PDF]

Translational Andrology and Urology, 2017
The expert panel made a tremendous effort to propose guidelines on the emerging trends of sperm DNA fragmentation testing and its clinical utility based on the available latest scientific evidence (1). Panel presented it in a systematic manner by a practical approach with four common clinical case scenarios.
openaire   +2 more sources

Impact of Methylparaben on Cumulus Cell DNA Integrity and Porcine Oocyte Developmental Competence In Vitro

Journal of Applied Toxicology, EarlyView.
ABSTRACT Parabens (PBs) are compounds widely used as preservatives in personal care products, food, and pharmaceuticals. Methylparaben (MePB) is the most used by different industries due to its chemical properties and low cost. The high daily human exposure to these compounds has raised concerns about their potential effects on health, particularly on ...
Yenny Ramírez‐Jara, Brenda Casado, Miguel Betancourt, Adyeni Barajas‐Salinas, Eduardo Casas, Gabriela Hurtado‐Alvarado, Juan José Rodríguez‐Mercado, Alma López, Iván Bahena, Lizbeth Juárez‐Rojas, Leticia González‐Núñez, Fahiel Casillas   +11 more
wiley   +1 more source

Combined sperm selection techniques to boost the success of in Vitro Fertilization (IVF) and Intra Cytoplasmic Sperm Injection (ICSI) [PDF]

Research Journal of Applied Biotechnology
This study aimed to assess the effectiveness of combined methods of Density gradient centrifugation and swim-up (D.G.C/S. U) and Density gradient centrifugation and zeta potential (D.G.C/Z) in semen samples to treat sperm abnormality, decrease DNA ...
Dina Abd El-baseer, bahgat Elifky, Khaled, Salem, Ebrahim Sabra   +3 more
doaj   +1 more source

Commentary: sperm DNA fragmentation testing in action [PDF]

Translational Andrology and Urology, 2017
The expert panel proposed a guideline on the clinical utility of sperm DNA fragmentation testing (1). Rapid advancement in the field of sperm DNA testing over the last two decades was summarized and structurally presented by the four clinical scenarios in an evidence-based approach.
openaire   +2 more sources

Male age : Negative impact on sperm DNA fragmentation [PDF]

, 2019
The main goal of semen processing in Assisted Reproductive Techniques (ART) is to select sperm with good viability and, at the same time, remove Reactive Oxygen Species (ROS) sources (such as leukocytes) and reduce the percentage of morphologically ...
Arruzzolo L., Levi-Setti P. E., Negri L., Albani E., Gurrieri B., Borroni E. M., Castellano S.   +6 more
core   +1 more source

Assessment of Gold‐Mediated Male Reproductive Dysfunction in Male WISTAR Rats Through Sperm Analysis and Testosterone Measurement

Journal of Applied Toxicology, EarlyView.
ABSTRACT Gold has been used for centuries in both ornamental and medicinal contexts. More recently, gold compounds, containing ions or nanoparticles, have attracted attention for their anti‐inflammatory, anticancer, and diagnostic applications. Therefore, concerns about systemic toxicity and biodistribution have prompted investigations into the ...
Samira Maghraoui, Adrian Florea, Leila Tekaya   +2 more
wiley   +1 more source

Fragmentation index of DNA sperm in llama semen (Lama glama) [PDF]

, 2017
DNA fragmentation of spermatozoa is an important indicator of seminal quality and fertility. The quality of the genetic information contained in the DNA molecule transmitted by the spermatozoa is important for the proper development of the embryo.
Ampuero, Enrique, Mendoza, Melisa, Ccalta, Ruth, Quispe, Wini, Cucho, Hernan, Ordonez, Cesar, Huanca, Nancy, Hanzen, Christian   +7 more
core  

Correlation between standard sperm parameters and sperm DNA fragmentation from 11,339 samples [PDF]

Conventional semen parameters have long been considered fundamental in male fertility analyses. However, doubts have been raised regarding the clinical utility of the assessment of spermatozoa (sperm) DNA damage.
Tingting Yang (166111), Fuping Li (9097369), Bin Zhou (84959), Yelin Jia (18396940), Lin Yu (221619), Jinyan Xu (437590), Lijuan Ying (14206982), Yan Zheng (61178)   +7 more
core   +1 more source