Results 131 to 140 of about 16,246 (249)

Semen Cryopreservation in Testicular Cancer: Before or After Orchidectomy?

open access: yesAndrology, EarlyView.
ABSTRACT Background Fertility preservation in patients with testicular cancer remains a clinical priority, yet the optimal timing for sperm cryopreservation—before or after orchidectomy—remains a matter of debate. Objectives The aim of this study was to determine the optimal timing for semen cryopreservation and the best‐quality sample for ART.
Alessandra Buonacquisto   +12 more
wiley   +1 more source

Microfluidic Intracytoplasmic Sperm Injection (MICSI): A Novel Platform for Sperm Isolation, Selection, and Injection Into Oocytes

open access: yesAndrology, EarlyView.
ABSTRACT Background Infertility is a pressing global health concern, affecting one in six couples worldwide. The failure rate for assisted reproductive technologies (ART) cycles remains at approximately 78%, with limited improvements often attributed to a lack of technological innovation.
Mehran Dabiri   +3 more
wiley   +1 more source

Impact of Chemotherapy on Sperm Functional Characteristics in Patients With Testicular Germ Cell Tumours

open access: yesAndrology, EarlyView.
ABSTRACT Background Testicular germ cell tumours (TGCT) are the most common malignancies among young men and represent a major threat to reproductive health. Both the disease itself and oncological treatments, particularly chemotherapy, can compromise spermatogenesis and semen quality.
Ondrej Sanovec   +18 more
wiley   +1 more source

Peroxiredoxin 4 Involved in Spermatogenesis by Affecting Oxidative Stress and Ferroptosis

open access: yesAndrology, EarlyView.
ABSTRACT Background The main functions of testes are sperm production and androgen secretion in testicular befitting microenvironment. Excessive level of the reactive oxygen species (ROS) from metabolism and cellular events can lead to oxidative stress (OS) and ferroptosis, which injure the functions of mitochondria and endoplasmic reticulum (ER) of ...
Shuning Yuan   +10 more
wiley   +1 more source

Boosting Male Fertility: The Impact of Gonadotropin Therapy on Hypogonadotropic Hypogonadism—A Systematic Review and Meta‐Analysis

open access: yesAndrology, EarlyView.
ABSTRACT Background Male hypogonadotropic hypogonadism typically presents with azoospermia and is one of the few causes of infertility amenable to a medical intervention. Gonadotropin therapy offers a chance to restore spermatogenesis and fertility in these individuals.
Manou Huijben   +3 more
wiley   +1 more source

Limited Utility of a Test‐Yolk Buffer Semen Extender for Preserving Human Semen Parameters for Use in a Diagnostic Setting

open access: yesAndrology, EarlyView.
ABSTRACT Background Identification of a preservation medium that accurately retains semen parameters would be advantageous for men requiring semen analysis by allowing them to produce sperm samples at home rather than on site or even facilitate ‘mail order’ semen analysis.
Alessia Schadwell   +5 more
wiley   +1 more source

Computer‐Assisted Sperm Analysis (CASA) Versus Manual Evaluation and the Clinical Significance of Sperm Hyperactivated Motility

open access: yesAndrology, EarlyView.
Abstract Background Semen analysis remains the first‐line diagnostic test for male infertility, although it is affected by operator subjectivity. Computer‐assisted sperm analysis (CASA) is proposed to improve objectivity; however, its accuracy and clinical relevance remain uncertain.
Maria Emanuela Ragosta   +8 more
wiley   +1 more source

Hyperactivation and Tyrosine Phosphorylation of Cryopreserved Stallion Spermatozoa in Relation to Conventional In Vitro Fertilization Blastocyst Production

open access: yesAndrology, EarlyView.
ABSTRACT Background Challenges in establishing clinical conventional in vitro fertilization (IVF) in horses include variation in sperm and oocyte quality, which can be affected by mare age. Extended preincubation of stallion spermatozoa has resulted in successful IVF.
Raul A. Gonzalez‐Castro   +6 more
wiley   +1 more source

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