Based on the integrated analysis of follicular fluid metabolites and microbial communities in patients with PCOS, this study reveals significant dysregulation in the follicular microenvironment. Key metabolites including D‐glucose and 25‐hydroxycholesterol show marked alterations, while microbial communities such as Alicyclobacillus and Terrimonas ...
Manfei Si +6 more
wiley +1 more source
Correlation of the sperm DNA fragmentation index with semen parameters and its impact on fresh embryo transfer outcomes-a retrospective study. [PDF]
Wan XJ +7 more
europepmc +1 more source
Deciphering mRNA Translation During Sperm Capacitation: A New Frontier in Fertility Research
ABSTRACT Male infertility accounts for approximately 50% of infertility cases, with nearly 30% remaining unexplained after standard evaluations. This highlights the need for a better understanding of sperm function to advance diagnostic and therapeutic strategies. Sperm were long considered translationally quiescent; however, emerging evidence suggests
Saurabh Tiwari +2 more
wiley +1 more source
The correlation between abnormal Krüger strict morphology and the sperm DNA fragmentation index. [PDF]
Ranzato TSGA +5 more
europepmc +1 more source
Is sperm hyaluronic acid binding ability predictive for clinical success of intracytoplasmic sperm injection: PICSI vs. ICSI? [PDF]
Bodnár, Béla +7 more
core +1 more source
Abstract Background Varicocoele is a common cause of male infertility, affecting spermatogenesis through increased testicular temperature, venous stasis, and oxidative stress. Microsurgical subinguinal varicocelectomy improves semen quality, whereas intrauterine insemination is widely used for mild male factor infertility.
Yanlin Ma +8 more
wiley +1 more source
Walking Among Pioneers - Sperm DNA Fragmentation and a Growing Focus on Male Factor Infertility. [PDF]
Coward RM.
europepmc +1 more source
Abstract Background Predicting male fertility in farm animals remains a challenge. Seminal plasma (SP) contains a high amount of heterogeneous seminal extracellular vesicles (sEVs), believed involved in reproductive processes and maybe key to understanding male fertility.
Isabel Barranco +6 more
wiley +1 more source
Global Andrology Forum Clinical Guidelines on the Relevance of Sperm DNA Fragmentation in Reproductive Medicine. [PDF]
Çayan S +57 more
europepmc +1 more source
Advanced Paternal Age Impacts Common Loci in the Sperm and Placenta DNA Methylomes
ABSTRACT Background Epidemiological studies have reported an association between advanced paternal age at conception and an increased risk of neurodevelopmental disorders in offspring, such as autism spectrum disorder. Evidence suggests that DNA methylation alterations in spermatozoa of older men may be transmitted to the feto‐placental unit and ...
Julia Barnwell +12 more
wiley +1 more source

