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Understanding sperm DNA fragmentation [PDF]
Translational Andrology and Urology, 2017 We greatly value the commentary by Dr. Gosalvez on the “Clinical utility of sperm DNA fragmentation testing: practice recommendations based on clinical scenarios” by Agarwal et al. (1). The author initiated his well-written note with an overview of the structural and physiologic significance of sperm DNA on male reproduction addressing its ...
Majzoub, Ahmad +2 more
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Sperm DNA Fragmentation in Reproductive Medicine
Journal of Human Reproductive Sciences, 2022 ABSTRACT Approximately 15% of the world's couples suffer from infertility during their reproductive period of which the male factor is responsible for 50% of cases. Male factor infertility is multifactorial in origin, and sperm DNA fragmentation (SDF) has also been linked to male infertility including idiopathic male ...
Ahmed T Alahmar +2 more
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Progress in Research on Sperm DNA Fragmentation [PDF]
Medical Science Monitor, 2020 With the increasing incidence of male infertility, routine detection of semen is insufficient to accurately assess male fertility. Infertile men, who have lower odds of conceiving naturally, exhibit high levels of sperm DNA fragmentation (SDF). The mechanisms driving SDF include abnormal spermatogenesis, oxidative stress damage, and abnormal sperm ...
Qiu, Ying +3 more
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A perspective on sperm DNA fragmentation [PDF]
Translational Andrology and Urology, 2017 The paper on sperm DNA fragmentation by Ashok Agarwal et al . summarizes the currently available DNA fragmentation tests and discusses the role of sperm function tests in the intracytoplasmic sperm injection (ICSI) era (1). The authors have summarized the clinical utility of sperm DNA fragmentation test and have provided recommendations based on ...
Pandiyan, Natarajan +2 more
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Male Infertility and Sperm DNA Fragmentation [PDF]
Open Access Macedonian Journal of Medical Sciences, 2018 BACKGROUND: One of the main factors affecting male infertility is DNA fragmentation in sperm. Male infertility is a heterogeneous group of disorders, known causes account for only 30-50%, and unknown cause (idiopathic) constitute the rest. Infertility involves nearly 15% of couples in the reproductive age, and only the male problem involves about 40 ...
Afrim Zeqiraj +7 more
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A cost for high levels of sperm competition in rodents: Increased sperm DNA fragmentation [PDF]
, 2016 Spermcompetition, a prevalent evolutionary process inwhich the spermatozoa of two or more males compete for the fertilization of the same ovum, leads to morphological and physiological adaptations, including increases in energetic metabolism that may ...
Soler, Ana J. +7 more
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Sperm DNA and detection of DNA fragmentations in sperm [PDF]
Urology Research and Practice, 2019 Abstract The questionable effectiveness of routine sperm parameters in determining male factor infertility problems and increasing the success rates of assisted reproductive techniques have led to the investigation of more detailed sperm parameters that could affect the male fertility and reproduction.
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Sperm DNA fragmentation testing [PDF]
Translational Andrology and Urology, 2017 The editors of this book, Drs. Ashok Agarwal, Ahmad Majzoub, Chak-Lam Cho and Sandro Esteves, are to be congratulated for bringing together an extensive tome on the evaluation and management of sperm DNA fragmentation. The perspectives from North America, South America, Europe, Asia and the rest of the world provide an interesting snapshot into ...
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The relationship between sperm viability and DNA fragmentation rates [PDF]
, 2018 Background In humans, sperm DNA fragmentation rates have been correlated with sperm viability rates. Reduced sperm viability is associated with high sperm DNA fragmentation, while conversely high sperm viability is associated with low ...
Garbens, Alaina +6 more
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A guide to sperm DNA fragmentation testing [PDF]
Translational Andrology and Urology, 2017 A conundrum exists in the field of male infertility as in many other areas of medical study. It is described by the adage that advises one to not order a test or exam if you don’t know what to do with the results. The urologists’ conundrum is: how to use the information we have learned about abnormalities in sperm chromatin, specifically DNA ...
Lynne, Charles M., Brackett, Nancy L.
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