Results 61 to 70 of about 39,103 (266)

Sperm DNA fragmentation and oxidation are independent of malondialdheyde

Reproductive Biology and Endocrinology, 2011
Background There is clinical evidence to show that sperm DNA damage could be a marker of sperm quality and extensive data exist on the relationship between DNA damage and male fertility status.
Gargouri Jalel, Ben Hamida Afifa, Abdallah Fatma, Elleuch Henda, Chakroun Nozha, Zribi Nassira, Fakhfakh Faiza, Keskes Leila   +7 more
doaj   +1 more source

Amphibian sperm DNA fragmentation [PDF]

, 2016
There are extremely limited studies that have investigated DNA fragmentation in amphibians and even less information exists pertaining to DNA fragmentation in the spermatozoa. A DNA fragmentation assay applied and validated for amphibian spermatozoa would not only provide the first evidence of this phenomenon in a new major taxon, but also prove a ...
openaire   +2 more sources

Reactive oxygen species and sperm DNA fragmentation [PDF]

Translational Andrology and Urology, 2017
Dr. Dada demonstrated her extensive knowledge about sperm DNA fragmentation (SDF) in her elegantly written commentary with a comprehensive discussion on issues such as genetic health of offspring, value of SDF testing in lifestyle factors, modification of SDF by oocyte, role of sperm preparation, concept of reductive stress, methodology of SDF testing,
Agarwal, Ashok, Cho, Chak-Lam, Esteves, Sandro C., Majzoub, Ahmad   +3 more
openaire   +2 more sources

Cancer Cell‐Intrinsic Cholesterol Induces Lipid‐Associated Macrophage Differentiation via SP1 Palmitoylation to Promote Prostate Cancer Progression

Advanced Science, EarlyView.
Cancer cell‐intrinsic cholesterol promotes the S‐palmitoylation of SP1, increasing its nuclear translocation and driving the transcription and secretion of MDK, which in turn facilitates the differentiation of macrophages into a lipid‐associated phenotype.
Shirong Peng, Weilong Lin, Zean Li, Ruilin Zhuang, Shengmeng Peng, Bingheng Li, Bingliang Chen, Yong Luo, Yuan Ou, Wei Zhuang, Tao Du, Kaiwen Li, Hai Huang   +12 more
wiley   +1 more source

Effect of microsurgical varicocelectomy on sperm DNA fragmentation in infertile men

Middle East Fertility Society Journal, 2011
Objectives: To examine the effect of microsurgical varicocelectomy on the sperm DNA damage in infertile men. Setting: Private clinical practice. Design: Prospective study.
Sherif Ghazi, Howida Abdelfattah
doaj   +1 more source

Is There a Causal Association between Genotoxicity and the Imposex Effect? [PDF]

, 2006
There is a growing body of evidence that indicates common environmental pollutants are capable of disrupting reproductive and developmental processes by interfering with the actions of endogenous hormones.
Colborn T, Collins MKL, Cooke H, Depledge MH, Gibbs PE, Harring KE, Harris JO, Josephine A. Hagger, Jörg Oehlmann, Laruelle F, Michael H. Depledge, Smith BS, Susan Jobling, Tamara S. Galloway   +13 more
core   +2 more sources

Sperm swim-up techniques and DNA fragmentation [PDF]

Human Reproduction, 2001
Swim-up techniques for sperm separation may have detrimental effects on sperm DNA. We wished to determine whether the normal swim-up method with centrifugation used in our laboratory, which involves a centrifugation step, was harmful to sperm compared with swim-up without centrifugation.Semen samples were obtained from patients undergoing IVF or ...
E V, Younglai, D, Holt, P, Brown, A, Jurisicova, R F, Casper   +4 more
openaire   +2 more sources

CellPolaris: Transfer Learning for Gene Regulatory Network Construction to Guide Cell State Transitions

Advanced Science, EarlyView.
CellPolaris decodes how transcription factors guide cell fate by building gene regulatory networks from transcriptomic data using transfer learning. It generates tissue‐ and cell‐type‐specific networks, identifies master regulators in cell state transitions, and simulates TF perturbations in developmental processes.
Guihai Feng, Xin Qin, Jiahao Zhang, Wuliang Huang, Yiyang Zhang, Wentao Cui, Yao Chen, Shirui Li, Wenhao Liu, Yao Tian, Yana Liu, Jingxi Dong, Ping Xu, Zhenpeng Man, Guole Liu, Zhongming Liang, Xinlong Jiang, Xiaodong Yang, Pengfei Wang, Ge Yang, Hongmei Wang, Xuezhi Wang, Ming‐Han Tong, Yuanchun Zhou, Shihua Zhang, Yiqiang Chen, Yong Wang, Xin Li   +27 more
wiley   +1 more source

Guidelines on sperm DNA fragmentation testing [PDF]

Translational Andrology and Urology, 2017
Male factor subfertility is present in more than 50% of the couples treated with assisted reproductive techniques. Routine semen analysis provides information on semen volume as well as sperm concentration, motility, and morphology. Standardized methods have been published by the World Health Organization (WHO) (1).
openaire   +2 more sources

Clinical usefulness of sperm DNA fragmentation testing [PDF]

Translational Andrology and Urology, 2017
The search for the best biomarker for the diagnosis of male infertility is more evident in recent years as conventional semen analysis is not always an optimal predictor of male fertility. Since the advent of the intra-cytoplasmic sperm injection (ICSI) for male factor infertility, the pace of research related to sperm functional assays has slowed down.
Varghese, Alex C., Tan, Grace, Chan, Peter, Tan, Seang Lin   +3 more
openaire   +2 more sources