Results 91 to 100 of about 14,205 (205)

Loss‐of‐Function Variants in CCDC189 Cause Human Oligoasthenoteratozoospermia by Disrupting Sperm Flagellar and Acrosomal Architecture

Andrology, EarlyView.
ABSTRACT Background Oligoasthenoteratozoospermia (OAT), characterized by reduced sperm count, impaired motility, and abnormal morphology, is a major cause of male infertility with substantial genetic heterogeneity. However, the underlying genetic etiology remains unresolved in a large proportion of affected individuals.
Jianteng Zhou, Ghulam Mustafa, Tingting Lin, Jingwei Ye, Huan Zhang, Hanwei Jiang, Kexin Yang, Guoning Huang, Qinghua Shi   +8 more
wiley   +1 more source

Proposed models showing the role of myosin II and myosin VI in spermatid differentiation.

, 2019
(A) Proposed model of the role of myosin II and myosin VI in spermatid differentiation. Myosin II and myosin VI play distinct roles to regulate RB formation and cytoplasm segregation.
Junyan Hu (813762), Xiaochen Wang (235611), Shiya Cheng (6593378), Xin Li (51274), Sun Liu (474179), Mengmeng Wu (3602447), Yubing Liu (428536), Haibin Wang (219428)   +7 more
core   +1 more source

Sperm Head–Tail Coupling Apparatus Diversity and Common Themes Among Species

Andrology, EarlyView.
ABSTRACT Background A stable connection between the sperm head (containing the nucleus and acrosome) and tail (containing the axoneme, mitochondrial sheath, and periaxonemal structures) is critical for fertility. This connection is mediated by a series of nuclear, cytoplasmic, and centriole components that make up the head–tail coupling apparatus (HTCA)
Danielle B. Buglak, Brian J. Galletta, Nasser M. Rusan   +2 more
wiley   +1 more source

Microbial Metabolites Bridge Environmental Stress and Male Infertility Through a Gut–Immune Axis

Medicine Bulletin, EarlyView.
Yunchuan Tian, Xinyao Tang, Ying Shen
wiley   +1 more source

Diabetes‐Induced Testicular Injury: Potential Protective Roles of Curcumin, Garcinia kola, and Momordica charantia in Rats

Andrology, EarlyView.
ABSTRACT Background Diabetes mellitus (DM) induces multifaceted cellular and structural alterations in the male reproductive system, thereby predisposing to infertility. Objectives This study aimed to evaluate the morphological, stereological, biochemical, histopathological, and ultrastructural changes induced by DM in testicular tissue, and to ...
Ayşenur Kaya Mutlu, Süleyman Kaplan
wiley   +1 more source

Intracytoplasmic spermatid injection and in vitro maturation: fact or fiction?

Clinics, 2013
Intracytoplasmic injection with testicular spermatozoa has become a routine treatment in fertility clinics. Spermatozoa can be recovered in half of patients with nonobstructive azoospermia.
Veerle Vloeberghs, Greta Verheyen, Herman Tournaye   +2 more
doaj  

Comparative description and discussion of spermiogenesis and spermatozoal ultrastructure in some species of Heptapteridae and Pseudopimelodidae (Teleostei: Siluriformes)

Neotropical Ichthyology
The data obtained in the present study on spermiogenesis and spermatozoal ultrastructure of Pseudopimelodidae and Heptapteridae show that they share some characteristics, but greatly differ from each other. The main differences are the occurrence of type
Irani Quagio-Grassiotto, Maria Angélica Spadella, Márcio de Carvalho, Claudio Oliveira   +3 more
doaj   +1 more source

Sperm Mitochondrial DNA Copy Number and Nuclear DNA Methylation Across Clinical and Non‐Clinical Preconception Cohorts

Andrology, EarlyView.
ABSTRACT Background Sperm mitochondrial DNA copy number is an emerging marker of male fertility, with elevated mtDNAcn associated with poor semen quality across various populations. Sperm DNA methylation has also been previously demonstrated to be negatively correlated with semen parameters in IVF cohorts.
Savni Sawant, Karolina Nowak, Amanda L. Paskavitz, Emily Houle, Ricardo P. Bertolla, Lidia Minguez‐Alarcon, Russ Hauser, J. Richard Pilsner   +7 more
wiley   +1 more source

Localization of the KIFC1-like protein and microtubules in intermediate spermatid in O. tankahkeei.

, 2013
The distribution of KIFC1-like protein and microtubules are observed by IF and IEM. (A) Microtubules were tightly attached to the nuclear periphery (arrowhead).
Fu-Qing Tan (317434), Wan-Xi Yang (317438), Wei Wang (17594), He-Ming Yu (358709), Jun-Quan Zhu (358708)   +4 more
core   +1 more source

Spatiotemporal Expression of ARRDC5 in Mammalian Spermatogenesis

Andrology, EarlyView.
ABSTRACT Background Spermiogenesis is the final phase of sperm development during which haploid round spermatids transform into specialized spermatozoa and occurs across distinct stages of sperm production in the seminiferous epithelium. Abnormalities in this process lead to malformations and an inability of sperm to fertilize eggs.
LeeLa D. Robinson, Jon M. Oatley
wiley   +1 more source