Sperm Telomere Interactions Are Impaired in Testicular Cancer Before and After Adjuvant Therapy
ABSTRACT Background No study has yet explored telomere length or interaction in sperm nuclei of testicular cancer (TC) patients exposed to chemotherapy or radiotherapy. However, sperm telomere dynamics have emerged as a potential marker in male infertility.
Benoit Berby +10 more
wiley +1 more source
The H2-receptor antagonist cimetidine is an antiulcer drug also used for the treatment of cancer due to its antiangiogenic effect. However, this drug has caused structural changes in the seminiferous tubules.
Flávia L Beltrame, Estela Sasso-Cerri
doaj +1 more source
SOX30 Governs Synaptonemal Complex Assembly and Homologous Recombination in Male Meiosis
The transcription factor SOX30 directly binds promoter regions of SYCE1 and SYCE2 to mediate their transcriptional activation, thereby enabling proper assembly of central elements within the synaptonemal complex. Structural destabilisation of the synaptonemal complex in Sox30 KK spermatocytes triggers synaptic discontinuity, impairs homologous ...
Kangle Liu +16 more
wiley +1 more source
Abstract In the context of current global change, variations in water temperature are one of the environmental conditions with serious consequences for marine life, including reproductive processes. In the small spotted catshark Scyliorhinus canicula, spermatogenesis occurs in spermatocysts composed of synchronously developing germ cells associated ...
Fabian Jeanne +4 more
wiley +1 more source
Zfy genes are required for efficient meiotic sex chromosome inactivation (MSCI) in spermatocytes [PDF]
During spermatogenesis, germ cells that fail to synapse their chromosomes or fail to undergo meiotic sex chromosome inactivation (MSCI) are eliminated via apoptosis during mid-pachytene.
Burgoyne, Paul S +4 more
core +3 more sources
Abstract Yellowstone cutthroat trout Oncorhynchus virginalis bouvieri in Yellowstone Lake are the focus of intensive conservation efforts due to the threat of predation by invasive lake trout Salvelinus namaycush. Suppression gillnetting has reduced the abundance of predatory lake trout, and the Yellowstone cutthroat trout population is recovering ...
Michelle A. Briggs +3 more
wiley +1 more source
Fraksi Heksan Ekstrak Biji Pepaya Muda Dapat Menghambat Proses Spermatogenesis Mencit Jantan Lebih Besar Daripada Fraksi Metanol Ekstrak Biji Papaya Muda [PDF]
Fraksi ekstrak heksan mengandung dua golongan zat aktif yang bersifat antifertilitas yaitu golongan steroid dan golongan triterpenoid yang diperkirakan bersifat antifertilitas, walupun mekanisme kerjanya belum jelas.
Satriyasa, B. K. (Bagus)
core
Human meiosis IV. The elimination of synaptonemal complex fragments from metaphase I bivalents of human spermatocytes [PDF]
Søren W. Rasmussen, Preben Bach Holm
openalex +1 more source
Review of expansion microscopy combined with advanced imaging modalities
Abstract Expansion microscopy (ExM) is a powerful high‐resolution imaging technique that enhances the spatial resolution of conventional light microscopy by physically enlarging biological specimens by embedding and cross‐linking them in a swellable polymer network.
Natalie Woo, Claire M. Brown
wiley +1 more source
RADIATION INDUCED X-Y EXCHANGE AND NONDISJUNCTION IN SPERMATOCYTES OF THE IMMATURE TESTIS OF DROSOPHILA [PDF]
S. Zimmering, C K Wu
openalex +1 more source

