Results 21 to 30 of about 58,630 (199)

TRiC Is a Structural Component of Mammalian Sperm Axonemes

Cytoskeleton, EarlyView.
ABSTRACT The TRiC chaperonin is responsible for folding ~5%–10% of the proteome in eukaryotic cells. Our recent cryo‐electron microscopy studies of axonemes from diverse mammalian cell types led to the surprising discovery that a fully assembled TRiC chaperonin is a structural component of mammalian sperm flagella, where it is tethered to the radial ...
Alan Brown, Miguel Ricardo Leung, Tzviya Zeev‐Ben‐Mordehai, Rui Zhang   +3 more
wiley   +1 more source

Decoding RNA–Protein Interactions: Methodological Advances and Emerging Challenges

Advanced Genetics, EarlyView.
This review provides a comprehensive comparison of RNA‐ and protein‐centric methodologies for investigating RNA–protein interactions, emphasizing their respective advantages, limitations, and suitable applications. It highlights recent technological innovations, outlines strategic method selection criteria, and addresses key challenges.
Wenkai Yi, Jian Yan
wiley   +1 more source

Pregnancy via Testicular Sperm Extraction for Anejaculation After Neuroblastoma Surgery

IJU Case Reports, EarlyView.
ABSTRACT Background Surgical treatment of a neuroblastoma, a malignant tumor of the sympathetic nervous system, may result in ejaculatory disorder. There are no reports examining ejaculation disorders after neuroblastoma surgery. Case Presentation The patient was a 31‐year‐old Japanese male who had undergone surgery for neuroblastoma of the abdomen at ...
Jurii Karibe, Teppei Takeshima, Daiji Takamoto, Takashi Kawahara, Kimito Osaka, Jun‐ichi Teranishi, Kazuhide Makiyama, Hiroji Uemura, Yasushi Yumura   +8 more
wiley   +1 more source

Histopathological Features of the Testes of a Patient With Congenital Lipoid Adrenal Hyperplasia

IJU Case Reports, EarlyView.
ABSTRACT Introduction Congenital lipoid adrenal hyperplasia (CLAH) is a type of congenital adrenal hyperplasia characterized by reduced steroid production. Patients with this endocrine disorder as well as chromosome 46,XY have testes and female external genitalia. Because these individuals are usually raised as female, the testes are removed.
Takuya Sakata, Kentaro Mizuno, Daisuke Matsumoto, Hidenori Nishio, Atsushi Suzuki, Kohei Aoyama, Atsushi Ishida, Takahiro Yasui, Haruo Mizuno, Yutaro Hayashi   +9 more
wiley   +1 more source

Bilateral High Intra‐Abdominal Testes Successfully Treated With Multistage Fowler–Stephens Orchiopexy to Preserve Testicular Function

IJU Case Reports, EarlyView.
ABSTRACT Introduction A case of bilateral high intra‐abdominal testes successfully treated with multistage Fowler–Stephens orchiopexy is reported. Case Presentation A 6‐month‐old boy with bilateral nonpalpable testes was diagnosed with a left intra‐abdominal testis located immediately caudal to the spleen on magnetic resonance imaging and laparoscopy ...
Akari Hiraguri, Yuichi Sato, Junya Hata, Yusuke Kirihana, Akihisa Hasegawa, Satoru Meguro, Kanako Matsuoka, Seiji Hoshi, Souichiro Ogawa, Yoshiyuki Kojima   +9 more
wiley   +1 more source

Transient Azoospermia Induced by Valganciclovir Treatment for Cytomegalovirus Infection in a Reproductive Male After Kidney Transplant: A Case Report

IJU Case Reports, EarlyView.
ABSTRACT Introduction Spermatogenic dysfunction is a side effect of valganciclovir, which is commonly used to treat cytomegalovirus infections. Here, we report the case of a reproductive man who underwent kidney transplantation and was diagnosed with azoospermia after valganciclovir treatment for cytomegalovirus infection.
Kosuke Mieda, Shunta Hori, Mitsuru Tomizawa, Kuniaki Inoue, Tatsuo Yoneda, Yuji Nitta, Yasushi Nakai, Makito Miyake, Nobumichi Tanaka, Kiyohide Fujimoto   +9 more
wiley   +1 more source

Pyriproxyfen Disrupts the Ongoing Spermatogenesis Wave in Danio rerio Potentially Mediated by Voltage‐Dependent Calcium Channels and Protein Kinase C

Journal of Applied Toxicology, EarlyView.
ABSTRACT Pyriproxyfen (PPX) is an analog of the juvenile hormone from insects. Following our previous studies, for the ex vivo short‐term effect, we chose 10−9 M pyriproxyfen to analyze the morphology of spermatogenesis wave cells. In silico docking and ADMET (Absorption, Distribution, Metabolism, Excretion, Toxicity) studies were carried out to ...
Bruna Antunes Zaniboni, Vanessa Staldoni de Oliveira, Gabriel Adan Araujo Leite, Valdelúcia Maria Alves de Souza Grinevicius, Rozangela Curi Pedrosa, Fátima Regina Mena Barreto Silva   +5 more
wiley   +1 more source

Atopic Dermatitis in Childhood and Biomarkers of Male Reproductive Health: A Danish National Birth Cohort Study

JEADV Clinical Practice, EarlyView.
This study found no indication of an adverse effect of childhood atopic dermatitis on biomarkers of male reproductive health. On the contrary, we observed some indications of slightly higher sperm concentration and lower follicle‐stimulating hormone (FSH) and luteinizing hormone (LH).
Camilla Lomholt Kjersgaard, Anne Gaml‐Sørensen, Linn Håkonsen Arendt, Sandra Søgaard Tøttenborg, Karin Sørig Hougaard, Gunnar Toft, Onyebuchi A. Arah, Jens Peter Bonde, Mette Deleuran, Cecilia Høst Ramlau‐Hansen   +9 more
wiley   +1 more source

Increasing acidification does not affect sexual reproduction of a solitary zooxanthellate coral transplanted at a carbon dioxide vent

Limnology and Oceanography, EarlyView.
Abstract The absorption of atmospheric carbon dioxide is causing significant changes to the carbonate chemistry of the ocean, in a phenomenon called ocean acidification. The latter makes it potentially more difficult for marine calcifiers like corals, to build their calcium carbonate structures, thus affecting their ability to survive and reproduce ...
Chiara Marchini, Fiorella Prada, Erik Caroselli, Francesca Gizzi, Valentina Airi, Dragana Paleček, Ilaria Zuccaro Destefani, Arianna Mancuso, Umberto Valdrè, Giuseppe Falini, Zvy Dubinsky, Stefano Goffredo   +11 more
wiley   +1 more source

Fertility Preservation Discussions And Decisions: Results From a Pilot Randomized Controlled Trial Among Adolescent Males With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives The Family‐centered Adolescent Sperm banking values clarification Tool (FAST) was developed to facilitate sperm banking communication and decision‐making pre‐cancer treatment. The FAST was tested in a pilot parallel randomized controlled trial (Fertility Preservation Discussions And Decisions: “FP‐DAD”‐NCT04268004 ...
Leena Nahata, Charleen I. Roche, Megan M. Griffith, Tanvi Karkare, Gwendolyn P. Quinn, Sarah H. O'Brien, Kelly Boone, Anthony Audino, Nicholas Yeager, Stacy Whiteside, Jennifer English, James L. Klosky, Joseph R. Rausch, Cynthia A. Gerhardt   +13 more
wiley   +1 more source