Results 121 to 130 of about 25,438 (286)

GSK3α‐mediated regulation of the RNA demethylase fat mass and obesity‐associated protein (FTO) during murine spermatogenesis

open access: yesThe FEBS Journal, EarlyView.
FTO regulates mRNA stability and translational efficiency through its m6A‐demethylation activity. GSK3 functions as an upstream regulator of FTO, leading to its inhibition via phosphorylation. In male germ cells, FTO activity is kept in check by GSK3α.
Neha Choudhari   +7 more
wiley   +1 more source

Histological analysis and spermatogonia detection in 3- and 2-month-old beagle testes.

open access: yes, 2014
Panels A and C are hematoxylin-eosin–stained testis sections in 3- and 2-month-old beagle testes, respectively. Only spermatogonia exist in 3- and 2-month-old beagle testes.
Kyung Hoon Lee (644872)   +9 more
core   +1 more source

Continuous darkness is associated with improved growth performance during a high‐temperature period and sex‐specific modulation of early gonadal development in juvenile yellowtail (Seriola quinqueradiata)

open access: yesJournal of Fish Biology, EarlyView.
Abstract Selective breeding of yellowtail (Seriola quinqueradiata) is expanding in Japan, increasing the demand for practical reproductive control tools in commercial aquaculture to reduce genetic risks from escapees. Slowing early gonadal development through environmental manipulation may support future sterilization strategies, particularly when ...
Yuya Hasegawa   +3 more
wiley   +1 more source

Black Carp Mylopharyngodon piceus reproductive development and maturation in the Mississippi River basin

open access: yesJournal of Fish Biology, EarlyView.
Abstract Black Carp Mylopharyngodon piceus are native to most major east Asian drainages and are internationally cultured for use as a food‐fish or a biological control for molluscs. We describe the reproductive biology of Black Carp from the growing invasive population in the Mississippi River basin through examination of incidental commercial ...
Patrick T. Kroboth   +5 more
wiley   +1 more source

NEUROG3 is a critical downstream effector for STAT3-regulated differentiation of mammalian stem and progenitor spermatogonia

open access: yes, 2012
Spermatogenesis relies on coordinated differentiation of stem and progenitor spermatogonia, and the transcription factor STAT3 is essential for this process in mammals.
Amy V. Kaucher   +5 more
core   +1 more source

Understanding extracellular vesicles in antiaging

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad   +3 more
wiley   +1 more source

Isolation and purification of type A spermatogonia from the bovine testis

open access: yes, 2002
The aim of this study was to isolate and purify bovine type A spermatogonia. Testes from 5-7-month-old calves were used to isolate germ cells using a two-step enzymatic digestion.
den Ouden, K.   +4 more
core   +1 more source

Constitutive Androstane Receptor Regulates Germ Cell Homeostasis, Sperm Quality, and Male Fertility via Akt‐Foxo1 Pathway

open access: yesAdvanced Science
Male sexual function can be disrupted by exposure to exogenous compounds that cause testicular physiological alterations. The constitutive androstane receptor (Car) is a receptor for both endobiotics and xenobiotics involved in detoxification.
Mélusine Monrose   +16 more
doaj   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney   +4 more
wiley   +1 more source

Gonadal development in scorpion mud‐turtles, Kinosternon scorpioides, in a controlled environment

open access: yesThe Anatomical Record, Volume 309, Issue 11, Page 3455-3466, November 2026.
Stage 20 was identified as the critical point for gonadal differentiation in Kinosternon scorpioides, providing key insights into sex determination. These findings enhance conservation strategies by supporting reproductive management and population viability in both in situ and ex situ programs. Abstract Research on gonadal development including sexual
Brenda Braga   +4 more
wiley   +1 more source

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