Results 101 to 110 of about 25,438 (286)

The expression of Cyclin D1 in gonocytes and spermatogonia.

, 2012
A) Total RNA from isolated gonocytes and spermatogonia (three biological replicates) was reverse transcribed before gene specific amplification. The resultant data was analysed using the 2e-ΔΔT calculation to determine mRNA expression in spermatogonia ...
Skye C. McIver (170151), Danielle M. Santarelli (170167), Brett Nixon (117179), Shaun D. Roman (170175), Simone J. Stanger (170159), Eileen A. McLaughlin (116618)   +5 more
core   +1 more source

Assessing a Model for a Complex Systemic Disorder—The Value of Male Mice With a Supernumerary X Chromosome for Klinefelter Syndrome Research

Andrology, EarlyView.
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley   +1 more source

Diacerein Disrupts Testicular Homeostasis: The Essential Role of Basal Cytokines in Maintaining Sertoli Cell Integrity and the Immune Microenvironment

Andrology, EarlyView.
ABSTRACT Background Pro‐inflammatory cytokines, TNF and IL‐1B, are essential for testicular homeostasis. Diacerein, an anti‐inflammatory drug, inhibits these cytokines, impairing M2 macrophages and Leydig cells (LCs). However, its impact on Sertoli cells (SCs) and M1 (CD68) macrophages remains unknown.
Elide Loise Freitas de Jesus, André Acácio Souza da Silva, Olumide Stephen Akinsomisoye, Erick J. R. Silva, Paulo Sérgio Cerri, Salmo Azambuja de Oliveira, Estela Sasso‐Cerri   +6 more
wiley   +1 more source

Cryopreservation did not affect spermatogonia global methylation profile in Senegalese sole (Solea senegalensis)

Spermatogonia cryopreservation is a method to preserve valuable genomes from both maternal and paternal origin. The damage associated with the application of this technology on post-thaw cell quality is important to assess, including at the epigenetic ...
Brionne, Aurélien, Fatsini Fernández, Elvira, Fatsini, Elvira, Laizé, Vincent, Cabrita, Elsa, Labbé, Catherine, Almeida, Maria Mafalda, Almeida, M. Mafalda   +7 more
core   +1 more source

Ultrastructure of spermatogonia and primary spermatocytes of C57BL6J mice

, 2001
The three types of spermatogonia were confirmed. Type A spermatogonia have a large nucleus and loose chromatin and are poor in endoplasmic reticulum.
Silva, JRCP, Martins, MRFB
core   +1 more source

Diabetes‐Induced Testicular Injury: Potential Protective Roles of Curcumin, Garcinia kola, and Momordica charantia in Rats

Andrology, EarlyView.
ABSTRACT Background Diabetes mellitus (DM) induces multifaceted cellular and structural alterations in the male reproductive system, thereby predisposing to infertility. Objectives This study aimed to evaluate the morphological, stereological, biochemical, histopathological, and ultrastructural changes induced by DM in testicular tissue, and to ...
Ayşenur Kaya Mutlu, Süleyman Kaplan
wiley   +1 more source

Single-cell gene expression analysis reveals diversity among human spermatogonia.

, 2017
STUDY QUESTION Is the molecular profile of human spermatogonia homogeneous or heterogeneous when analysed at the single-cell level? SUMMARY ANSWER Heterogeneous expression profiles may be a key characteristic of human spermatogonia, supporting the ...
Yoon J, Huge A, Grindberg RV, Schöler HR, Schlatt S, Kliesch S, Voss R, Terwort N, Seggewiss J, Neuhaus N   +9 more
core   +1 more source

Sperm Mitochondrial DNA Copy Number and Nuclear DNA Methylation Across Clinical and Non‐Clinical Preconception Cohorts

Andrology, EarlyView.
ABSTRACT Background Sperm mitochondrial DNA copy number is an emerging marker of male fertility, with elevated mtDNAcn associated with poor semen quality across various populations. Sperm DNA methylation has also been previously demonstrated to be negatively correlated with semen parameters in IVF cohorts.
Savni Sawant, Karolina Nowak, Amanda L. Paskavitz, Emily Houle, Ricardo P. Bertolla, Lidia Minguez‐Alarcon, Russ Hauser, J. Richard Pilsner   +7 more
wiley   +1 more source

Isolation of the synchronized A spermatogonia from adult vitamin A-deficient rat testes

, 1996
A method for isolating A spermatogonia from the adult vitamin A-deficient (VAD) rat testis is described. After removal, the testes were decapsulated and tubules were dissected.
Morena, A. R., van Dissel-Emiliani, F. M., Boitani, C., de rooij, D. G., van Pelt, A. M., Stefanini, M., Gaemers, I. C.   +6 more
core   +1 more source

Microbial Metabolites Bridge Environmental Stress and Male Infertility Through a Gut–Immune Axis

Medicine Bulletin, EarlyView.
Yunchuan Tian, Xinyao Tang, Ying Shen
wiley   +1 more source