Results 91 to 100 of about 25,438 (286)
Clonal arrangement of Lin28 positive spermatogonia in the seminiferous tubules.
Whole mount staining of seminiferous tubules was performed to find out the size of Lin28 positive spermatogonia subpopulations. Lin28 positive cells were spermatogonia As, (blue arrow head) and Apr (yellow arrow head).
Heejun Jung (637709) +2 more
core +1 more source
QUANTITATION OF INTERCELLULAR CONNECTIONS BETWEEN SPERMATOGONIA IN THE MOUSE
Spermatogonial stem cells (SSCs) are critical in the male reproductive process, as they can either self-renew or proliferate into progenitor cells that differentiate to enter meiosis and eventually form functional sperm.
Cook, Kenneth
core +2 more sources
Reproductive Challenges of the Ageing Female: A Comprehensive Narrative Review
ABSTRACT Changes in societal norms over the last few decades have resulted in novel family planning trends, notably delayed childbearing and increased maternal age at the birth of the first child. Despite advances in reproductive medicine, ageing poses significant challenges.
Sofia Bitzika +6 more
wiley +1 more source
Arf protein expression in mitotically dividing spermatogonia.
Protein expression in sections of seminiferous tubules were determined by immunofluorescence analysis. (A) p19Arf (green, left panel) is expressed in spermatogonia that intervene between Sox9-expressing Sertoli cells (red, middle panel) in the ...
Scott Keeney (47164) +4 more
core +1 more source
Abstract Background It is well‐established that spermatogenesis, semen quality, and reproductive hormones are interlinked. It is, however, less well‐described how various specific testicular histopathologies are linked to reproductive hormones and semen quality.
Gülizar Saritas +6 more
wiley +1 more source
The use of deidentified organ donor testes for research
Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova +4 more
wiley +1 more source
The role of iron in normal and impaired testicular function
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer +2 more
wiley +1 more source
SALL4 is downregulated in differentiating spermatogonia.
(A) SALL4 and cKIT are co-expressed in chained Aal spermatogonia. (B) SALL4 becomes downregulated as spermatogonia differentiate. In contrast, cKIT expression persists in differentiated germ cells. (C) Quantification of SALL4/cKIT co-staining showed that
Kathrin Gassei (103294) +1 more
core +1 more source
G9a co-suppresses LINE1 elements in spermatogonia [PDF]
Background: Repression of retrotransposons is essential for genome integrity and the development of germ cells. Among retrotransposons, the establishment of CpG DNA methylation and epigenetic silencing of LINE1 (L1) elements and the intracisternal A ...
Stefano Comazzetto +9 more
core +1 more source
ABSTRACT Testicular germ cell tumors (TGCT) are the leading malignancy in adolescent and young adult males, yet the immunological and cellular mechanisms governing their tumor microenvironment (TME) remain poorly understood. Here, we present a comprehensive review of TGCT pathobiology with a focus on the immune landscape, particularly the role of tumor‐
R Islam +7 more
wiley +1 more source

