Results 71 to 80 of about 17,740 (206)

Diacerein Disrupts Testicular Homeostasis: The Essential Role of Basal Cytokines in Maintaining Sertoli Cell Integrity and the Immune Microenvironment

Andrology, EarlyView.
ABSTRACT Background Pro‐inflammatory cytokines, TNF and IL‐1B, are essential for testicular homeostasis. Diacerein, an anti‐inflammatory drug, inhibits these cytokines, impairing M2 macrophages and Leydig cells (LCs). However, its impact on Sertoli cells (SCs) and M1 (CD68) macrophages remains unknown.
Elide Loise Freitas de Jesus, André Acácio Souza da Silva, Olumide Stephen Akinsomisoye, Erick J. R. Silva, Paulo Sérgio Cerri, Salmo Azambuja de Oliveira, Estela Sasso‐Cerri   +6 more
wiley   +1 more source

Testicular Biopsies in Adolescent and Adult Andrological Patients: The EAA Clinical Guidelines

Andrology, EarlyView.
ABSTRACT Background Histological evaluation of testicular tissue is central to the assessment of infertile men, particularly those at an increased risk of testicular germ cell tumors (TGCT). Traditionally, testicular biopsies have been used primarily for diagnostic purposes, such as the detection of germ cell neoplasia in situ (GCNIS). With advances in
Lise Aksglaede, George Kanakis, Ewa Rajpert‐De Meyts, Davor Jezek, Ferran Algaba, Gert Dohle, Jolanta Slowikowska‐Hilczer, Sabine Kliesch, Hermann M. Behre, Csilla Krausz, Dimitrios G. Goulis, Niels Jørgensen   +11 more
wiley   +1 more source

THE EFFECT OF CHRONIC EXPOSURE OF NICOTINE INHALATION TO THE COUNT OF SPERMATOGONIA, SERTOLI CELLS AND LEYDIG CELLS OF YOUNG WHITE RAT WISTAR STRAIN

Jurnal Urologi Indonesia, 2019
Objective: To analyze the difference in the number of spermatogonia, leydig cells and sertoli cells in young age of  white mice Wistar strain after inhalation of chronic nicotine exposure.
Aril Rizaldi, Doddy M Soebadi, Soetojo Soetojo   +2 more
doaj   +1 more source

Diabetes‐Induced Testicular Injury: Potential Protective Roles of Curcumin, Garcinia kola, and Momordica charantia in Rats

Andrology, EarlyView.
ABSTRACT Background Diabetes mellitus (DM) induces multifaceted cellular and structural alterations in the male reproductive system, thereby predisposing to infertility. Objectives This study aimed to evaluate the morphological, stereological, biochemical, histopathological, and ultrastructural changes induced by DM in testicular tissue, and to ...
Ayşenur Kaya Mutlu, Süleyman Kaplan
wiley   +1 more source

Animal modeling methods for oligospermia: A review

Asian Pacific Journal of Reproduction
Oligospermia, characterized by a low sperm count in semen, is a major cause of male infertility and may result from various factors including infections, lifestyle choices, retrograde ejaculation, tumors, hormonal imbalances, drug treatments, and ...
Dinesh Sharma, Nitesh Parsaila, Archana Navale, Sagar Shinde, Nishant Patidar, Prachi Nahar, Ajay Shelke, Nilay Solanki   +7 more
doaj   +1 more source

Sperm Mitochondrial DNA Copy Number and Nuclear DNA Methylation Across Clinical and Non‐Clinical Preconception Cohorts

Andrology, EarlyView.
ABSTRACT Background Sperm mitochondrial DNA copy number is an emerging marker of male fertility, with elevated mtDNAcn associated with poor semen quality across various populations. Sperm DNA methylation has also been previously demonstrated to be negatively correlated with semen parameters in IVF cohorts.
Savni Sawant, Karolina Nowak, Amanda L. Paskavitz, Emily Houle, Ricardo P. Bertolla, Lidia Minguez‐Alarcon, Russ Hauser, J. Richard Pilsner   +7 more
wiley   +1 more source

Anatomical and Histological Structures of the Male Reproductive System of Chalcophora mariana (Linnaeus, 1758) (Coleoptera: Buprestidae): Light and Scanning Electron Microscopy Study

Acta Zoologica, EarlyView.
ABSTRACT This study presents the first detailed morphological analysis of the male reproductive system of Chalcophora mariana (Linnaeus, 1758) using stereo microscopy, light microscopy, and scanning electron microscopy. The male reproductive system of C.
Hicret Arslan, Selami Candan
wiley   +1 more source

Anatomical and Histological Descriptions of the Male Reproductive System of the Alfalfa Weevil of Hypera postica (Gyllenhal, 1813) (Coleoptera: Curculionidae) Using Light and Scanning Electron Microscopies

Acta Zoologica, EarlyView.
ABSTRACT Features of the reproductive organs, such as the number of testicular follicles, testis colour and the morphology of the glands, can be used as systematic characters. For this purpose, this paper was the first description of the male reproductive system anatomy and histology of Hypera postica (Gyllenhal, 1813) (Coleoptera: Curculionidae), a ...
Nurcan Özyurt Koçakoğlu, Selami Candan, Hicret Arslan, Mustafa Güllü   +3 more
wiley   +1 more source

Optimization of Conditions for Cryopreservation of Enriched Spermatogonial Stem Cells in Olive Flounder (Paralichthys olivaceus)

Cells
Spermatogonial stem cells (SSCs) are pivotal in surrogate broodstock technology. However, species-specific protocols for the efficient enrichment and long-term preservation of SSCs in olive flounder (Paralichthys olivaceus) are not yet fully established.
Ja Young Cho, A Young Jeon, Hyun Tae Kim, Jung-Ha Kang, Jae Hun Cheong, Jae Hoon Choi   +5 more
doaj   +1 more source

Cloning and Expression Analysis of a Giant Gourami Vasa-Like cDNA

Hayati Journal of Biosciences, 2011
Molecular marker is useful in the development of testicular cells transplantation for detecting donor-derived germ cells in the recipient gonad. In this study, a giant gourami (Osphronemus goramy) vasa-like gene (GgVLG) was cloned and characterized for ...
ALIMUDDIN, IRMA ANDRIYANI, MUHAMMAD ZAIRIN JUNIOR, HARTON ARFAH, ANNA OCTAVERA, ODANG CARMAN, GORO YOSHIZAKI   +6 more
doaj   +1 more source