Results 51 to 60 of about 17,684 (208)

Ursolic Acid Alleviates Orchitis via Modulating Ferroptosis in Peritubular Myoid Cells of Testis

Animal Research and One Health, EarlyView.
Ursolic acid modulates key ferroptosis‐related pathways in the peritubular myoid cells of the testis in forest musk deer. ABSTRACT Chronic stress adversely affects reproductive health, increasing susceptibility to pathologies such as orchitis. Additionally, the maintenance of iron homeostasis is essential for preserving the function of the testicles ...
Yang Wang, Tianqi Jin, Zexin Chen, Ye Gong, Qimin Liu, Zifang Wu, Heran Cao, Yan Li, Yuyan Liu, Tianhao Yang, Zhihong Jiang, Wuzi Dong   +11 more
wiley   +1 more source

Transfer of a Mouse Artificial Chromosome into Spermatogonial Stem Cells Generates Transchromosomic Mice

Stem Cell Reports, 2017
The introduction of megabase-sized large DNA fragments into the germline has been a difficult task. Although microcell-mediated chromosome transfer into mouse embryonic stem cells (ESCs) allows the production of transchromosomic mice, ESCs have unstable ...
Takashi Shinohara, Kanako Kazuki, Narumi Ogonuki, Hiroko Morimoto, Shogo Matoba, Kei Hiramatsu, Kazuhisa Honma, Teruhiko Suzuki, Takahiko Hara, Atsuo Ogura, Mitsuo Oshimura, Mito Kanatsu-Shinohara, Yasuhiro Kazuki   +12 more
doaj   +1 more source

Epigenetic Regulation of TET1-SP1 During Spermatogonia Self-Renewal and Proliferation

Frontiers in Physiology, 2022
Spermatogonia are the source of spermatogenic waves. Abnormal spermatogonia can cause ab-normal spermatogenic waves, which manifest as spermatogenic disorders such as oligospermia, hypospermia, and azoospermia.
Lingling Liu, Jin Wang, Shenghua Wang, Mudi Wang, Yuanhua Chen, Liming Zheng   +5 more
doaj   +1 more source

Histological Characterization and Comparative Transcriptomic Analysis of Gonads During Early Sex Differentiation in the Northern Snakehead (Channa argus)

Animal Research and One Health, EarlyView.
This study delineates the early sex differentiation timeline in the northern snakehead (Channa argus). These findings provide a foundation for future sex‐control breeding in this economically important species. ABSTRACT The northern snakehead (Channa argus) is an economically important aquaculture species in China.
Chaonan Sun, Donglei Sun, Haishen Wen, Xin Qi, Chao Li, Xiaoyan Zhang, Yun Li   +6 more
wiley   +1 more source

Cracd Marks the First Wave of Meiosis during Spermatogenesis and Is Mis-Expressed in Azoospermia Mice

Journal of Developmental Biology, 2020
Testicular development starts in utero and maturation continues postnatally, requiring a cascade of gene activation and differentiation into different cell types, with each cell type having its own specific function.
Paige L. Snider, Olga Simmons, Simon J. Conway   +2 more
doaj   +1 more source

Prmt7 Downregulation in Mouse Spermatogonia Functions through miR-877-3p/Col6a3

Life, 2022
Protein arginine methyltransferases 7 (Prmt7) is expressed in male germ cells, including primordial germ cells, gonocytes, and spermatogonia. Our previous study demonstrated that Prmt7 downregulation reduced the proliferation of GC-1 cells (a cell line ...
Hongmei Gao, Mingrui Zhang, Jiankang Guo, Zhiguo Liu, Fei Guo, Bingyuan Wang, Yulian Mu   +6 more
doaj   +1 more source

Heat Stress in Quail: Impacts on Health and Productivity, and Mitigation Strategies

Animal Research and One Health, EarlyView.
Heat stress disrupts physiological homeostasis in quail, inducing oxidative stress, immune dysregulation, and metabolic imbalance, which impair growth, reproduction, product quality, and welfare. Integrating nutritional, environmental, and genetic–epigenetic strategies enhances thermotolerance, sustains productivity, and supports climate‐smart quail ...
T. A. Eletu, I. A. Anjola, L. O. Fasasi, D. P. Fadipe, A. T. Afuye, F. O. Fasanya, O. E. Oke   +6 more
wiley   +1 more source

Cell Cycle of Spermatogonia in Mouse Testis [PDF]

Investigative Radiology, 1979
This report measures the spermatogonial cell cycles and their constituent phases of proliferating type A, intermediate (In), and type B cells in the testis of the young mouse, and analyzes the cell cycle and cell population kinetic parameters, such as growth fractions and cell-birth rates, from /sup 3/HTdR autoradiographic data.
openaire   +3 more sources

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

Animal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen, Debashri Mondal, Thangapalam Jawahar Abraham   +2 more
wiley   +1 more source

The effect of immobilization stress on the HPG axis (hypothalamic - pituitary - gonad) hormones and the number of spermatogonia [PDF]

Journal of Advanced Biomedical Sciences, 2013
Background & Objective: Stress has different effects on the living organisms. In this study the effect of immobilization stress the HPG (hypothalamic - pituitary - gonad axis) hormones secretion and the number of spermatogonia was studied in adult male ...
ahmad mozafar, mojtaba keshavarz, parvin zareian, Habiboalah Johary, hossein kargar jahromy, Shirzad Hoseini   +5 more
doaj