Results 51 to 60 of about 25,438 (286)

Spermatogenesis disorders in sterlet (Acipenser ruthenus Linnaeus, 1758) in water area of the Kakhovka Reservoir

Ribogospodarsʹka Nauka Ukraïni
Purpose. To conduct histological studies of sterlet spermatogenesis in technogenic conditions. To determine the level of reproductive system disorders, to identify possible causes of abnormalities.
М. Koziy
doaj   +1 more source

Organotypic Rat Testicular Organoids for the Study of Testicular Maturation and Toxicology

Frontiers in Endocrinology, 2022
An in vitro system to study testicular maturation in rats, an important model organism for reproductive toxicity, could serve as a platform for high-throughput drug and toxicity screening in a tissue specific context. In vitro maturation of somatic cells
Sadman Sakib, Sadman Sakib, Nathalia de Lima e Martins Lara, Brandon Christopher Huynh, Brandon Christopher Huynh, Ina Dobrinski, Ina Dobrinski   +6 more
doaj   +1 more source

Functional Sex Reversal in Adult Gonochoristic Teleosts is Mediated by Ovarian Germline Stem Cell Plasticity and Somatic Cell Transdifferentiation

Advanced Science, EarlyView.
Oocytes play crucial roles in maintaining ovarian fate in adult gonochoristic fish. Targeted oocyte ablation with aromatase inhibition triggers the activation of surviving germline stem cells and the transdifferentiation of somatic cells from granoulosa/theca to Sertoli/Leydig lineages, inducing a complete and functional female‐to‐male sex reversal ...
Yang Yang, Liechao Yu, Wanchang Zhang, Gary Wessel, Ruiyi Chen, Weihua Hu, Dongdong Xu   +6 more
wiley   +1 more source

CIP2A promotes spermatogonia proliferation cell autonomously.

, 2012
(A) qRT-PCR analyses demonstrating reduction of CIP2A transcription in spermatogonia treated with siCIP2A. Spermatogonia were isolated from seminiferous tubules of 10-day-old mice and CIP2A mRNA expression was assessed after 7 days of CIP2A siRNA ...
Edward K. Chan (176088), Christophe Côme (109084), Sami Ventelä (176062), Markku Kallajoki (114542), Juho-Antti Mäkelä (176069), Jorma Toppari (157894), Leni Mannermaa (176079), Jukka Westermarck (176095), Robin M. Hobbs (176074), Pier Paolo Pandolfi (2229)   +9 more
core   +1 more source

Isolation and identification of spermatogonia and spermatocytes.

, 2020
The images of spermatogonia (A, C) and spermatocytes (B, D) from yaks and cattleyaks under the inverted microscope with scale bars = 20 μm. The expression of marker genes for the spermatogonia and spermatocytes isolated from yaks (E) and cattleyaks (F).
Shixin Wu (2090413), Mujahid Ali Shah (8486556), Chuanfei Xu (8486550), Xin Cai (140935), Wangsheng Zhao (8486553), Hui Luo (588276), TserangDonko Mipam (8486547), Chuanping Yi (8486559), Jincheng Zhong (6245054)   +8 more
core   +1 more source

A change in the frequency of the degenerating spermatogonia in the rat [PDF]

Reproduction, 1980
Summary. In right and left testes of the same animals, the frequencies of degeneration of type A spermatogonia were almost equal. When one testis was removed, there was a negative correlation of the frequency of the degenerating spermatogonia in this testis and the other after 25 days.
S, Ohwada, H, Tamate
openaire   +2 more sources

BOULE is Essential for the Dynamic Disassembly of Heat Shock Granules in Male Germ Cells

Advanced Science, EarlyView.
BOULE orchestrates stress granule disassembly in germ cells via a two‐pronged mechanism: it promotes G3BP1 ubiquitination by upregulating TRIM27, generating a signal for VCP/FAF2 recruitment, and it maintains G3BP1 and FAF2 protein levels. BOULE deficiency disrupts disassembly complex formation, leading to impaired heat shock granule clearance ...
Xin Li, Nana Zhang, Zexin Bian, Baobao Geng, Liyun Cao, Peipei Liu, Zengming Li, Yan Zhao, Jun Tan   +8 more
wiley   +1 more source

New perspectives on fertility in transwomen with regard to spermatogonial stem cells

Reproduction and Fertility, 2023
Objective: Germ cells of transwomen are affected by gender-affirming hormone therapy (GAHT). Fertility will be lost after surgical intervention; thereby, fertility preservation becomes an increasingly imortant topic.
Jennifer Dabel, Florian Schneider, Joachim Wistuba, Sabine Kliesch, Stefan Schlatt, Nina Neuhaus   +5 more
doaj   +1 more source

Spermatogonia: stem cells with a great perspective [PDF]

Reproduction, 2001
Abstract Interest in spermatogonia has grown in recent years as a result of exciting developments in stem cell research in general and the development of new research tools allowing the isolation, culture and transplantation of these cells. This review focuses on the methodological breakthroughs and highlights the recent findings that
S, Meachem, V, von Schönfeldt, S, Schlatt   +2 more
openaire   +2 more sources

Prion‐Like Protein LENG8‐Mediated Nucleation Drives Stress Granule Assembly

Advanced Science, EarlyView.
LENG8 is a newly identified stress granule (SG) nucleator required for SG assembly. Following stress, nuclear LENG8 granules disassemble, allowing LENG8 to translocate into the cytoplasm and form independent nucleation foci. These foci fuse with canonical early G3BP1/TIA1 seeds via LENG8‐TIA1 binding to drive SG maturation.
Mingxing Zhang, Xin Wang, Yilan Teng, Zhicheng Wu, Jing Fan, Hongwen Zhu, Peng Dai   +6 more
wiley   +1 more source