Results 31 to 40 of about 25,438 (286)

The netrin-1 receptor UNC5C contributes to the homeostasis of undifferentiated spermatogonia in adult mice

open access: yesStem Cell Research, 2022
In adult testis, the cell mobility is essential for spermatogonia differentiation and is suspected to regulate spermatogonial stem cell fate. Netrin-1 controls cell migration and/or survival according to the cellular context. Its involvement in some self-
Vilma Barroca   +5 more
doaj   +1 more source

scRNA-seq Profiling of Human Testes Reveals the Presence of the ACE2 Receptor, A Target for SARS-CoV-2 Infection in Spermatogonia, Leydig and Sertoli Cells

open access: yesCells, 2020
In December 2019, a novel coronavirus (SARS-CoV-2) was identified in COVID-19 patients in Wuhan, Hubei Province, China. SARS-CoV-2 shares both high sequence similarity and the use of the same cell entry receptor, angiotensin-converting enzyme 2 (ACE2 ...
Zhengpin Wang, Xiaojiang Xu
doaj   +1 more source

Retinoic Acid Receptors Control Spermatogonia Cell-Fate and Induce Expression of the SALL4A Transcription Factor. [PDF]

open access: yesPLoS Genetics, 2015
All-trans retinoic acid (ATRA) is instrumental to male germ cell differentiation, but its mechanism of action remains elusive. To address this question, we have analyzed the phenotypes of mice lacking, in spermatogonia, all rexinoid receptors (RXRA, RXRB
Aurore Gely-Pernot   +10 more
doaj   +1 more source

Long-Term Wi-Fi Exposure From Pre-Pubertal to Adult Age on the Spermatogonia Proliferation and Protective Effects of Edible Bird’s Nest Supplementation

open access: yesFrontiers in Physiology, 2022
Children are vulnerable to the radiofrequency radiation (RFR) emitted by Wi-Fi devices. Nevertheless, the severity of the Wi-Fi effect on their reproductive development has been sparsely available.
Farah Hanan Fathihah Jaffar   +4 more
doaj   +1 more source

CG6015 controls spermatogonia transit-amplifying divisions by epidermal growth factor receptor signaling in Drosophila testes

open access: yesCell Death and Disease, 2021
Spermatogonia transit-amplifying (TA) divisions are crucial for the differentiation of germline stem cell daughters. However, the underlying mechanism is largely unknown.
Jun Yu   +9 more
doaj   +1 more source

The Dnmt3L ADD Domain Controls Cytosine Methylation Establishment during Spermatogenesis [PDF]

open access: yes, 2015
A critical aspect of mammalian gametogenesis is the reprogramming of genomic DNA methylation. The catalytically inactive adaptor Dnmt3L is essential to ensuring this occurs correctly, but the mechanism by which it functions is unclear.
Robert J. Schmitz   +32 more
core   +1 more source

Roles of Spermatogonial Stem Cells in Spermatogenesis and Fertility Restoration

open access: yesFrontiers in Endocrinology, 2022
Spermatogonial stem cells (SSCs) are a group of adult stem cells in the testis that serve as the foundation of continuous spermatogenesis and male fertility.
Lei Diao   +5 more
doaj   +1 more source

Mammalian germ cell migration during development, growth, and homeostasis

open access: yesReproductive Medicine and Biology, 2019
Background Germ cells represent one of the typical cell types that moves over a long period of time and large distance within the animal body. To continue its life cycle, germ cells must migrate to spatially distinct locations for proper development ...
Mizuho Kanamori   +3 more
doaj   +1 more source

Cryopreservation and transplantation of common carp spermatogonia - spermatogonia viability dataset

open access: yes, 2019
Dataset of spermatogonia viability assessment from optimization of cryopreservation and vitrification protocols.
Franek Roman, Franek Roman (6296585)
core   +2 more sources

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