Results 21 to 30 of about 17,740 (206)

Somatic ERK activation during transit amplification is essential for maintaining the synchrony of germline divisions in Drosophila testis [PDF]

Open Biology, 2018
Transit amplification (TA) of progenitor cells maintains tissue homeostasis by balancing proliferation and differentiation. In Drosophila testis, the germline proliferation is tightly regulated by factors present in both the germline and the neighbouring
Samir Gupta, Bhavana Varshney, Shambhabi Chatterjee, Krishanu Ray   +3 more
doaj   +1 more source

Filamin A Orchestrates Cytoskeletal Structure, Cell Migration and Stem Cell Characteristics in Human Seminoma TCam-2 Cells

Cells, 2020
Filamins are large dimeric F-actin cross-linking proteins, crucial for the mechanosensitive properties of a number of cell types. Due to their interaction with a variety of different proteins, they exert important regulatory functions.
Harald Welter, Carola Herrmann, Thomas Fröhlich, Florian Flenkenthaler, Katja Eubler, Hubert Schorle, Daniel Nettersheim, Artur Mayerhofer, Annette Müller-Taubenberger   +8 more
doaj   +1 more source

Data on in vivo phenotypes of GFRα1-positive spermatogonia stimulated by interstitial GDNF signals in mouse testes

Data in Brief, 2016
This article contains the data related to the research article “in vivo dynamics of GFRα1-positive spermatogonia stimulated by GDNF signals using a bead transplantation assay” (Uchida et al., 2016) [1].
Aya Uchida, Yoshiakira Kanai
doaj   +1 more source

Isolation and characterization of human spermatogonial stem cells

Reproductive Biology and Endocrinology, 2011
Background To isolate and characterization of human spermatogonial stem cells from stem spermatogonium. Methods The disassociation of spermatogonial stem cells (SSCs) were performed using enzymatic digestion of type I collagenase and trypsin.
Liu Shixue, Tang Ziwei, Xiong Tao, Tang Wei   +3 more
doaj   +1 more source

WIN18,446 enhances spermatogonial stem cell homing and fertility after germ cell transplantation by increasing blood-testis barrier permeability

The Journal of Reproduction and Development, 2023
Spermatogonial stem cells (SSCs) possess a unique ability to recolonize the seminiferous tubules. Upon microinjection into the adluminal compartment of the seminiferous tubules, SSCs transmigrate through the blood-testis barrier (BTB) to the basal ...
Hiroko MORIMOTO, Mito KANATSU-SHINOHARA, Takashi SHINOHARA   +2 more
doaj   +1 more source

Identification of fish spermatogenic cells through high-throughput immunofluorescence against testis with an antibody set

Frontiers in Endocrinology, 2023
Image-based identification and quantification of different types of spermatogenic cells is of great importance, not only for reproductive studies but also for genetic breeding.
Ding Ye, Tao Liu, Yongming Li, Yaping Wang, Wei Hu, Zuoyan Zhu, Yonghua Sun   +6 more
doaj   +1 more source

Feedback Regulation of the Proliferation of the Undifferentiated Spermatogonia In the Chinese Hamster By the Differentiating Spermatogonia

Cell Proliferation, 1985
AbstractIn the seminiferous epithelium the differentiating spermatogonia proliferate following a very strict synchronous pattern, and undergo the S phase during parts of particular epithelial stages. the undifferentiated spermatogonia do not divide synchronously and display maximum proliferative activity in stages XI‐III.
de rooij, D. G., Lok, D., Weenk, D.
openaire   +3 more sources

BRCA1 preserves genome integrity during the formation of undifferentiated spermatogonia

EMBO Reports
Undifferentiated spermatogonia, which form shortly after birth, consist of spermatogonial stem cells and progenitor spermatogonia that maintain homeostasis.
Peng Li, Licun Song, Longfei Ma, Chunsheng Han, Lejun Li, Lin-Yu Lu, Yidan Liu   +6 more
doaj   +1 more source

Spermatogenesis disorders in sterlet (Acipenser ruthenus Linnaeus, 1758) in water area of the Kakhovka Reservoir

Ribogospodarsʹka Nauka Ukraïni
Purpose. To conduct histological studies of sterlet spermatogenesis in technogenic conditions. To determine the level of reproductive system disorders, to identify possible causes of abnormalities.
М. Koziy
doaj   +1 more source

Stem Cell Differentiation Disperses Transcriptional Clusters via a Conserved Surface‐Condensate Trajectory

Advanced Science, EarlyView.
Stem cell differentiation follows a conserved surface condensate trajectory: H3K27ac super enhancers nucleate large RNA polymerase II clusters that grow and unfold before transcriptional activity disperses them. This work reveals how biophysical forces at enhancer surfaces dynamically build and dismantle stem cell transcription hubs, reshaping cell ...
Tim Klingberg, Irina Wachter, Agnieszka Pancholi, Matthias Akyel, Yomna Gohar, Priya Kumar, Ana Miguel Fernandes, Yuzhi Bao, Alica Schmidt‐Heydt, Marcel Piepers, Alicia Günthel, Marcel Sobucki, Elisa Kämmer, Süheyla Eroğlu‐Kayıkçı, Stephan Allgeier, Sylvia Erhardt, Vasily Zaburdaev, Carmelo Ferrai, Lennart Hilbert   +18 more
wiley   +1 more source