Results 21 to 30 of about 25,438 (286)

Grtp1 Safeguards Against Paternal Reproductive Aging and Intergenerational Behavioral Deficits by Preserving Redox Homeostasis. [PDF]

Adv Sci (Weinh)
This study identifies that Grtp1 maintains germline redox homeostasis by interacting with PRDX1/4‐TXN to antagonize paternal reproductive aging. Growth hormone restores Grtp1 expression, rectifies aberrant sperm DNA methylation, and ameliorates intergenerational anxiety and social deficits, highlighting the GH‐GRTP1 axis as a promising intervention ...
Liu Y, Liu S, Liang H, Yang J, Li Y, Yin J, Zhang X, Zhang Y, Bai D, Yan Z, Zhang Z, Jia Y, Liu K, Sheng Y, Xiang J, Xi C, Dong B, Lei X, Chen J, Wang H, Guo Y, Zhang Y, Gao S, Liu W.   +23 more
europepmc   +2 more sources

Effect of honey bee venom on the histological changes of testes and hormonal disturbance in diabetic mice [PDF]

Veterinary World, 2022
Background and Aim: Hyperglycemia associated with hyper- or hypo-insulinemia is a hallmark of type 2 diabetes mellitus, which is firmly linked to decreased male infertility.
Sattar J. J. AL-Shaeli, Talal Jabal Hussen, Ali M. Ethaeb   +2 more
doaj   +1 more source

Overexpression of lncRNA-Gm2044 in spermatogonia impairs spermatogenesis in partial seminiferous tubules

Poultry Science, 2022
: Long noncoding RNAs (lncRNAs) have been demonstrated to regulate reproduction in mammals. Our previous study revealed that the expression level of lncRNA-Gm2044 was obviously elevated in nonobstructive azoospermia with spermatogonial arrest.
Ke Hu, Yuanyuan Gao, Yifan Xu, Chaofan He, Kaixian Wang, Leina Li, Yaping Liao, Xiaohua Liu, Meng Liang   +8 more
doaj   +1 more source

Notch is a ligand of Draper mediating spermatogonia cell death. [PDF]

Nat Commun
Abo Romi H, Serhan N, Porat-Kuperstein L, Toledano H.   +3 more
europepmc   +3 more sources

Methodological approaches for spermatogonia population enrichment and effect of cryopreservation on Senegalese sole spermatogonia quality [PDF]

, 2022
Senegalese sole (Solea senegalensis) is an emerging species for aquaculture that shows reproductive issues in aquaculture conditions. The transplantation of cryopreserved spermatogonia into closely related species allows the production of surrogated ...
Almeida, Maria Mafalda Amaral Fonseca de
core   +1 more source

In Vitro Cytotoxicity Effects of Zinc Oxide Nanoparticles on Spermatogonia Cells

Cells, 2020
Zinc Oxide Nanoparticles (ZnO NPs) are a type of metal oxide nanoparticle with an extensive use in biomedicine. Several studies have focused on the biosafety of ZnO NPs, since their size and surface area favor entrance and accumulation in the body, which
Ana Rita Pinho, Filipa Martins, M. Elisabete V. Costa, Ana M. R. Senos, Odete A. B. da Cruz e Silva, Maria de Lourdes Pereira, Sandra Rebelo   +6 more
doaj   +1 more source

EFFECT OF DICHLORVOS PESTICIDE ON FERTILITY OF LABORATORY MALE MICE (Mus musculus L.) [PDF]

Basrah Journal of Veterinary Research, 2008
Dichlorvos is one of organophosphate insect pesticides which is widely distributed in environment. This study deals with the effect of this pesticide on sperms number , sperm abnormalities and spermatogenesis in laboratory male mice (Mus musculus L ...
Faris Shaker Kata
doaj   +1 more source

Spermatogonial Gene Networks Selectively Couple to Glutathione and Pentose Phosphate Metabolism but Not Cysteine Biosynthesis

iScience, 2021
Summary: In adult males, spermatogonia maintain lifelong spermatozoa production for oocyte fertilization. To understand spermatogonial metabolism we compared gene profiles in rat spermatogonia to publicly available mouse, monkey, and human spermatogonial
David Prokai, Ashutosh Pudasaini, Mohammed Kanchwala, Andrew T. Moehlman, Alexandrea E. Waits, Karen M. Chapman, Jaideep Chaudhary, Jesus Acevedo, Patrick Keller, Xing Chao, Bruce R. Carr, F. Kent Hamra   +11 more
doaj   +1 more source

Undifferentiated spermatogonia modulate their behavior via the expression of basement membrane protein laminin†. [PDF]

Biol Reprod
Kawabe Y, Yamada S, Shima Y, Tanemura K, Yoshida S, Hara K.   +5 more
europepmc   +2 more sources

RNA-binding protein Ptbp1 regulates alternative splicing and transcriptome in spermatogonia and maintains spermatogenesis in concert with Nanos3

The Journal of Reproduction and Development, 2020
PTBP1, a well-conserved RNA-binding protein, regulates cellular development by tuning posttranscriptional mRNA modification such as alternative splicing (AS) or mRNA stabilization. We previously revealed that the loss of Ptbp1 in spermatogonia causes the
Manami SENOO, Hiroshi HOZOJI, Yu ISHIKAWA-YAMAUCHI, Takashi TAKIJIRI, Sho OHTA, Tomoyo UKAI, Mio KABATA, Takuya YAMAMOTO, Yasuhiro YAMADA, Masahito IKAWA, Manabu OZAWA   +10 more
doaj   +1 more source