Results 41 to 50 of about 17,684 (208)

New perspectives on fertility in transwomen with regard to spermatogonial stem cells

open access: yesReproduction and Fertility, 2023
Objective: Germ cells of transwomen are affected by gender-affirming hormone therapy (GAHT). Fertility will be lost after surgical intervention; thereby, fertility preservation becomes an increasingly imortant topic.
Jennifer Dabel   +5 more
doaj   +1 more source

PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility

open access: yesAdvanced Science, EarlyView.
PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao   +7 more
wiley   +1 more source

Spermatogenesis disorders in sterlet (Acipenser ruthenus Linnaeus, 1758) in water area of the Kakhovka Reservoir

open access: yesRibogospodarsʹka Nauka Ukraïni
Purpose. To conduct histological studies of sterlet spermatogenesis in technogenic conditions. To determine the level of reproductive system disorders, to identify possible causes of abnormalities.
М. Koziy
doaj   +1 more source

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

open access: yesAdvanced Science, EarlyView.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu   +10 more
wiley   +1 more source

In vitro propagation of XXY human Klinefelter spermatogonial stem cells: A step towards new fertility opportunities

open access: yesFrontiers in Endocrinology, 2022
Klinefelter Syndrome (KS) is characterized by a masculine phenotype, supernumerary sex chromosomes (47, XXY), and impaired fertility due to loss of spermatogonial stem cells (SSCs).
Guillermo Galdon   +17 more
doaj   +1 more source

Stem Cell Differentiation Disperses Transcriptional Clusters via a Conserved Surface‐Condensate Trajectory

open access: yesAdvanced Science, EarlyView.
Stem cell differentiation follows a conserved surface condensate trajectory: H3K27ac super enhancers nucleate large RNA polymerase II clusters that grow and unfold before transcriptional activity disperses them. This work reveals how biophysical forces at enhancer surfaces dynamically build and dismantle stem cell transcription hubs, reshaping cell ...
Tim Klingberg   +18 more
wiley   +1 more source

A change in the frequency of the degenerating spermatogonia in the rat [PDF]

open access: yesReproduction, 1980
Summary. In right and left testes of the same animals, the frequencies of degeneration of type A spermatogonia were almost equal. When one testis was removed, there was a negative correlation of the frequency of the degenerating spermatogonia in this testis and the other after 25 days.
S, Ohwada, H, Tamate
openaire   +2 more sources

Gonadal development in scorpion mud‐turtles, Kinosternon scorpioides, in a controlled environment

open access: yesThe Anatomical Record, EarlyView.
Stage 20 was identified as the critical point for gonadal differentiation in Kinosternon scorpioides, providing key insights into sex determination. These findings enhance conservation strategies by supporting reproductive management and population viability in both in situ and ex situ programs. Abstract Research on gonadal development including sexual
Brenda Braga   +4 more
wiley   +1 more source

Isolation and Characterization of Highly Pure Type A Spermatogonia From Sterlet (Acipenser ruthenus) Using Flow-Cytometric Cell Sorting

open access: yesFrontiers in Cell and Developmental Biology, 2021
Sturgeons are among the most ancient linages of actinopterygians. At present, many sturgeon species are critically endangered. Surrogate production could be used as an affordable and a time-efficient method for endangered sturgeons. Our study established
Xuan Xie   +13 more
doaj   +1 more source

Male reproductive system in stenopodidean shrimps: Unveiling basal reproductive traits in shrimp‐like Pleocyemata (Stenopodidae and Spongicolidae)

open access: yesThe Anatomical Record, EarlyView.
Abstract Stenopodidea represents one of the basal lineages within Pleocyemata, yet the male reproductive system (MRS) of this group remains poorly understood, with limited information available regarding its morphology and function. This study provides the first detailed description of the MRS in four stenopodidean shrimp species from two families ...
Caio Santos Nogueira   +2 more
wiley   +1 more source

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