Results 171 to 180 of about 9,914 (214)
Chromatin and Single-Cell RNA-Seq Profiling Reveal Dynamic Signaling and Metabolic Transitions during Human Spermatogonial Stem Cell Development [PDF]
Cell Stem Cell, 2017 Human adult spermatogonial stem cells (hSSCs) must balance self-renewal and differentiation. To understand how this is achieved, we profiled DNA methylation and open chromatin (ATAC-seq) in SSEA4+ hSSCs, analyzed bulk and single-cell RNA transcriptomes ...
Cecilia Lindskog +2 more
exaly +3 more sources
Role of Src family kinases and N-Myc in spermatogonial stem cell proliferation [PDF]
Developmental Biology, 2007 Spermatogonial stem cells are required for the initiation of spermatogenesis and the continuous production of sperm. In addition, they can acquire pluripotency and differentiate into derivatives of the three embryonic germ layers when cultured in the ...
Marie-Claude Hofmann, Martin Dym
exaly +2 more sources
Spermatogonial stem cell regulation and spermatogenesis [PDF]
Philosophical Transactions of the Royal Society B: Biological Sciences, 2010 This article will provide an updated review of spermatogonial stem cells and their role in maintaining the spermatogenic lineage. Experimental tools used to study spermatogonial stem cells (SSCs) will be described, along with research using these tools to enhance our understanding of stem cell biology and spermatogenesis.
Kyle Orwig +2 more
exaly +3 more sources
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Spermatogonial stem cell transplantation
Molecular and Cellular Endocrinology, 2000The development of the spermatogonial transplantation technique has given new impetus to research on spermatogonial stem cells. Possibilities opened by this technique include: (a) New ways to study fundamental aspects of spermatogenesis; (b) Generation of transgenic large domestic animals; (c) Protection of (young) male cancer patients from infertility
Izadyar, F. +4 more
openaire +3 more sources
2006
The biological activities of spermatogonial stem cells (SSCs) are the foundation for spermatogenesis and thus sustained male fertility. Therefore, understanding the mechanisms governing their ability to both self-renew and differentiate is essential.
Jon M, Oatley, Ralph L, Brinster
openaire +2 more sources
The biological activities of spermatogonial stem cells (SSCs) are the foundation for spermatogenesis and thus sustained male fertility. Therefore, understanding the mechanisms governing their ability to both self-renew and differentiate is essential.
Jon M, Oatley, Ralph L, Brinster
openaire +2 more sources
Spermatogonial Stem Cell Development
2002Spermatogonial stem cells originate from primordial germ cells (PGCs) that derive from epiblast cells (embryonal ectoderm) (Lawson and Pederson 1992). During fetal development the PGCs proliferate and migrate to the genital ridges, where they become enclosed in the seminiferous cords formed by Sertoli cell precursors.
de Rooij, D.G. +3 more
openaire +2 more sources
2012
The process of spermatogenesis is initiated and maintained by a rare population of single spermatogonial stem cells (SSCs). The SSCs are attached to the basement membrane of the seminiferous tubules and are characterized by typical morphological criteria.
Hossein Azizi +3 more
openaire +1 more source
The process of spermatogenesis is initiated and maintained by a rare population of single spermatogonial stem cells (SSCs). The SSCs are attached to the basement membrane of the seminiferous tubules and are characterized by typical morphological criteria.
Hossein Azizi +3 more
openaire +1 more source
Spermatogonial stem cells in the albino rat
American Journal of Anatomy, 1975AbstractThe existence of two classes of spermatogonial stem cells in the rat testis, i.e., reserve type A0 spermatogonia and renewing, types A1‐A4 spermatogonia, postulated by Clermont and Bustos‐Obregon (′68), was reexamined in a quantitative analysis of type A spermatogonia in both whole mounts of tubules and in radioautographed sections of testes ...
Y, Clermont, L, Hermo
openaire +2 more sources
Spermatogonial stem cells: unlimited potential
Reproduction, Fertility and Development, 2008Recent reports have demonstrated that adult cells can be reprogrammed to pluripotency, but mostly with genes delivered using retroviruses. Some of the genes are cancer causing; thus, these adult-derived embryonic stem (ES)-like cells cannot be used for therapy to cure human diseases.
M, Dym +4 more
openaire +2 more sources
2013
Spermatogonial stem cells (SSCs) constitute one of the most important stem cell systems in the adult body. SSCs are unipotent and respond for spermatogenesis in the male as they can only differentiate into sperms within the testicular niche. The long-term culture of SSCs without loss of their properties provides the opportunity to develop therapeutic ...
Ilya Chuykin +2 more
openaire +1 more source
Spermatogonial stem cells (SSCs) constitute one of the most important stem cell systems in the adult body. SSCs are unipotent and respond for spermatogenesis in the male as they can only differentiate into sperms within the testicular niche. The long-term culture of SSCs without loss of their properties provides the opportunity to develop therapeutic ...
Ilya Chuykin +2 more
openaire +1 more source