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Avian Biology Research, 2011
Testicular gonocytes differentiate into spermatogonia, and spermatogonial stem cells could be established by culturing spermatogonia in vitro. Testicular and ovarian gonocytes were identified as relatively large cells in a population of gonadal cells.
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Testicular gonocytes differentiate into spermatogonia, and spermatogonial stem cells could be established by culturing spermatogonia in vitro. Testicular and ovarian gonocytes were identified as relatively large cells in a population of gonadal cells.
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1993
Abstract Spermatogonial stem cells are responsible for the maintenance of spermatogenesis in the adult mammal. Knowledge of their regulation is important to understand the initiation of normal spermatogenesis, its recovery after toxic insults, and the modulation of fertility.
Marvin L Meistrich, Maria E A B van Beek
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Abstract Spermatogonial stem cells are responsible for the maintenance of spermatogenesis in the adult mammal. Knowledge of their regulation is important to understand the initiation of normal spermatogenesis, its recovery after toxic insults, and the modulation of fertility.
Marvin L Meistrich, Maria E A B van Beek
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Cryopreservation and Transplantation of Spermatogonial Stem Cells
2021Cryopreservation as a method that enables long-term storage of biological material has long been used for the conservation of valuable zebrafish genetic resources. However, currently, only spermatozoa of zebrafish can be successfully cryopreserved, while protocols for cryopreservation of eggs and embryos have not yet been fully developed ...
Zoran, Marinović +6 more
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Heterogeneity of Spermatogonial Stem Cells
2019Germ cells transfer genetic materials from one generation to the next, which ensures the continuation of the species. Spermatogenesis, the process of male germ cell production, is one of the most productive systems in adult tissues. This high productivity depends on the well-coordinated differentiation cascade in spermatogonia, occurring via their ...
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Is There a Clinical Future for Spermatogonial Stem Cells?
Current Stem Cell Research & Therapy, 2007Like every other adult stem cell in the human body, spermatogonial stem cells (SSCs) have the capacity to either renew themselves or to start the differentiation process, namely, spermatogenesis. Due to the continuation of the stem cell population in the testis, several possible options for preservation and re-establishment of the reproductive ...
Ellen, Goossens +3 more
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Spermatogonial stem‐cell renewal in the mouse
The Anatomical Record, 1971AbstractType A spermatogonia in the mouse can be separated into five successive classes on the basis of nuclear morphology and stage of the cycle in which they occur. Enumeration of all types throughout the cycle of the seminiferous epithelium reveals that the As spermatogonia are the stem cells.
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Regulation of the proliferation of spermatogonial stem cells
Journal of Cell Science, 1988ABSTRACT The proliferating cells in the seminiferous epithelium can be subdivided into the (morphologically) undifferentiated and the differentiating spermatogonia. In turn the undifferentiated spermatogonia can be subdivided according to their topographical arrangement into clones consisting of one cell, the A-single (As) spermatogonia,
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Spermatogonial Stem Cell Transplantation to the Testis
Cold Spring Harbor Protocols, 2017Spermatogonial stem cells (SSCs) are located in the basal region of the seminiferous tubules and provide a self-renewing reservoir from which progenitor spermatogonia arise and transiently amplify in number before transition to a differentiating state.
Shaun, Goodyear, Ralph, Brinster
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Advances in spermatogonial stem cell transplantation
Reviews of Reproduction, 2000Spermatogonial stem cell transplantation was first reported by Ralph Brinster's laboratory in 1994. It has proven to be a technological breakthrough in the study of both stem cells and Sertoli cell-germ cell interactions. This technique can be used to transfer testicular stem cells successfully from one animal to another of the same species (referred ...
D S, Johnston +2 more
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Cryopreserving and Thawing Spermatogonial Stem Cells
Cold Spring Harbor Protocols, 2017Spermatogonial stem cells (SSCs) can be cryopreserved and stored in liquid nitrogen, using relatively standard cryopreservation techniques. At a subsequent time, they can be thawed for subsequent culture and expansion and then transplanted to generate spermatogenesis.
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