Results 81 to 90 of about 5,422,149 (177)

Spermatogonia stem cells: A new pluripotent source for repairment in regenerative medicine

Research in Molecular Medicine, 2015
Recently new reports have proved the pluripotency of spermatogonial stem cells (SSCs) derived from male gonad. This pluripotent stem cells resembled Embryonic stem cells recognized as Embryonic Stem like cells (ES like cells).
Maryam Nazm-Bbojnordi, Hatef Ghasemi Hamidabadi   +1 more
doaj  

CRISPR/Cas9‐mediated Genome‐editing Reveals 10 Testis‐enriched Genes and One Non‐testis‐enriched Gene are Dispensable for Male Fecundity in Mice

Andrology, Volume 14, Issue 7, Page 2150-2159, October 2026.
ABSTRACT Background More than 1000 genes have been identified as predominantly expressed in the human testis. Advances in gene editing technologies have enabled the rapid and efficient generation of genetically engineered mice. This approach facilitates the screening of genes essential for spermatogenesis by analyzing knockout mouse models.
Yumiao Qiu, Keisuke Shimada, Masahito Ikawa   +2 more
wiley   +1 more source

SWI/SNF Complex Prevents Lineage Reversion and Induces Temporal Patterning in Neural Stem Cells [PDF]

, 2014
Members of the SWI/SNF chromatin-remodeling complex are among the most frequently mutated genes in human cancer, but how they suppress tumorigenesis is currently unclear.
Knoblich, Juergen A., Reichert, Heinrich, Burkard, Thomas R., Homem, Catarina C.F., Saini, Nidhi, Eroglu, Elif, Homem, Catarina C. F., Jiang, Yanrui   +7 more
core   +1 more source

Seminal Plasma Exosomal miRNA Profiling Reveals hsa‐miR‐7‐5p as a Key Regulator of Sperm Motility in Asthenozoospermia

Andrology, Volume 14, Issue 7, Page 2166-2179, October 2026.
ABSTRACT Background Asthenozoospermia is a significant contributing factor to male infertility. Accumulating evidence indicates that impaired sperm motility is closely linked to dysregulated microRNA expression during spermatogenesis. Seminal plasma exosomes are enriched with diverse microRNAs, which play pivotal roles in modulating sperm motility, the
Zhi‐Jian Zhu, Meng‐Li Cui, Wen‐Jing Yuan, Jia‐Ning Zhang, Shuo Zhang, Xi‐Qiao Yao, Ruo‐Qing Li, Jin‐Feng Li, En‐Zhong Li   +8 more
wiley   +1 more source

Peroxiredoxin 4 Involved in Spermatogenesis by Affecting Oxidative Stress and Ferroptosis

Andrology, Volume 14, Issue 7, Page 2329-2346, October 2026.
ABSTRACT Background The main functions of testes are sperm production and androgen secretion in testicular befitting microenvironment. Excessive level of the reactive oxygen species (ROS) from metabolism and cellular events can lead to oxidative stress (OS) and ferroptosis, which injure the functions of mitochondria and endoplasmic reticulum (ER) of ...
Shuning Yuan, Nini Wei, Weiwei Ma, Mengting Hu, Bei Zhang, Li Gao, Chao Gao, Xiaoyu Yang, Yan Meng, Jiayin Liu, Yugui Cui   +10 more
wiley   +1 more source

Deriving bovine embryonic stem-like cells in defined conditions [PDF]

, 2011
The first embryonic stem ES cell line was isolated from mouse in 1981 (Evans and Kaufman 1981; Martin1981). However, ESCs are only available in rodent species.
Muhammad Alahdal, Hadil, Hadil Muhammad Alahdal   +1 more
core  

Purification of Immature Neuronal Cells from Neural Stem Cell Progeny [PDF]

Large-scale proliferation and multi-lineage differentiation capabilities make neural stem cells (NSCs) a promising renewable source of cells for therapeutic applications.
Brent A Reynolds, اسفندياري, ابراهيم, Reynolds, Brent A, Maryam Rahman, Osborne, Geoffrey W, Dennis A Steindler, Adams, David J, Dennis A. Steindler, Takahiro Yasuda, Bjorn Scheffler, Brent A. Reynolds, Scheffler, Bjorn, Mohammad G Golmohammadi, گل محمدی, محمد قاسم, Geoffrey W Osborne, Hassan Azari, David J. Adams, Mohammad G. Golmohammadi, Deleyrolle, Loic P, Steindler, Dennis A, Ebrahim Esfandiari, Loic P Deleyrolle, آذری, حسن, Yasuda1, Takahiro, رحمان, مریم, David J Adams, Loic P. Deleyrolle, Geoffrey W. Osborne   +27 more
core   +2 more sources

TGF-beta signalling in the adult neurogenic niche promotes stem cell quiescence as well as generation of new neurons. [PDF]

, 2014
Members of the transforming growth factor (TGF)-b family govern a wide range of mechanisms in brain development and in the adult, in particular neuronal/glial differentiation and survival, but also cell cycle regulation and neural stem cell maintenance ...
Strauss, O., Aigner, L., Lehner, B., Kraus, Sabrina, Strauss, Olaf, Reitsamer, Herbert A., Marschallinger, Julia, Lehner, Bernadette, Couillard-Despres, Sebastien, Bogdahn, Ulrich, Couillard‐Despres, Sebastien, Kandasamy, M., Kraus, S., Couillard-Despres, S., Sander, P.R., Trümbach, Dietrich, Aigner, Ludwig, Bogdahn, U., Trümbach, D., Sander, Paul Ramm, Ramm Sander, Paul, Rivera, Francisco J., Ueberham, Uwe, Marschallinger, J., Kandasamy, Mahesh, Reitsamer, H.A., Rivera, F.J., Ueberham, U.   +27 more
core   +1 more source

Chromodomain Helicase DNA–Binding Proteins and Spermatogenesis: Current Advances

Andrology, Volume 14, Issue 7, Page 1962-1970, October 2026.
ABSTRACT Background Male infertility is a prevalent clinical condition, with approximately one‐third of cases classified as idiopathic, frequently stemming from impaired spermatogenesis because of dysregulated gene expression. Chromodomain helicase DNA‐binding (CHD) proteins are central chromatin remodelers that orchestrate this epigenetic regulation ...
Mingrui Zhang, Di Liu, Guoqiang Liu, Minggang Zhu, Feng Pan   +4 more
wiley   +1 more source

Expression profiling of stemness markers in testicular germline stem cells from neonatal and adult Swiss albino mice during their transdifferentiation in vitro

Stem Cell Research & Therapy
Background Spermatogonial stem cells (SSCs) were considered to be stem cells with limited potencies due to their existence in adult organisms. However, the production of spermatogonial stem cell colonies with broader differentiation capabilities in ...
Sivankutty Indu, Anandavally N. Devi, Mahitha Sahadevan, Jeeva Sengottaiyan, Asmita Basu, Shabith Raj K, Pradeep G. Kumar   +6 more
doaj   +1 more source