Results 81 to 90 of about 9,914 (214)
Establishment of a normal medakafish spermatogonial cell line capable of sperm production in vitro [PDF]
, 2004 Spermatogonia are the male germ stem cells that continuously produce sperm for the next generation. Spermatogenesis is a complicated process that proceeds through mitotic phase of stem cell renewal and differentiation, meiotic phase, and postmeiotic ...
Zhao, HB +9 more
core
Data in Brief, 2016 This article contains the data related to the research article “in vivo dynamics of GFRα1-positive spermatogonia stimulated by GDNF signals using a bead transplantation assay” (Uchida et al., 2016) [1].
Aya Uchida, Yoshiakira Kanai
doaj +1 more source
Andrology, EarlyView.ABSTRACT Background Sperm mitochondrial DNA copy number is an emerging marker of male fertility, with elevated mtDNAcn associated with poor semen quality across various populations. Sperm DNA methylation has also been previously demonstrated to be negatively correlated with semen parameters in IVF cohorts.
Savni Sawant +7 more
wiley +1 more source
Studies on the behaviour of human pancreatic carcinoma cell lines, with particular reference to stem cells [PDF]
, 2010 PhDStem cell therapy represents a potential -cell replacement strategy in diabetes and a pancreatic cancer (PC) stem cell is an attractive therapeutic target in this dire disease. However, a normal stem cell remains unidentified and proposed malignant
Guppy, Naomi J
core
A Noncanonical Protein Degradation Pathway That Regulates Germ Cell Maintenance
Cell Proliferation, EarlyView.SENP8 regulates a non‐canonical NEDD8‐dependent pathway to stabilize STAT1, promote CCL2/CCL5 transcription, and maintain germ cell proliferation and migration.
Meng Liu +11 more
wiley +1 more source
A single-cell view of spermatogonial stem cells
Current Opinion in Cell Biology, 2020 Spermatogonial stem cells (SSCs) are essential for long-term spermatogenesis and are the subject of considerable clinical interest, as 'SSC therapy' has the potential to cure some forms of male infertility. Recently, we have learned more about SSCs and spermatogenesis in general from a plethora of studies that performed single-cell RNA sequencing ...
Kun Tan, Miles F. Wilkinson
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Enrichment of Spermatogonial Stem Cells using Side Population in Teleost [PDF]
, 2014 Spermatogenesis originates from a small population of spermatogonial stem cells; this population can maintain continuous sperm production throughout the life of fish via self-renewal and differentiation.
Yoshizaki, Goro +7 more
core +2 more sources
Spermatogonia stem cells: A new pluripotent source for repairment in regenerative medicine
Research in Molecular Medicine, 2015 Recently new reports have proved the pluripotency of spermatogonial stem cells (SSCs) derived from male gonad. This pluripotent stem cells resembled Embryonic stem cells recognized as Embryonic Stem like cells (ES like cells).
Maryam Nazm-Bbojnordi +1 more
doaj
Lysine l‐Lactylation: Bridging Metabolism, Chromatin and Disease
Cell Proliferation, EarlyView.Enzymatic regulation of KL‐la. The enzymatic regulation of KL‐la involves two distinct pathways for L‐lactate accumulation: intracellular production through glycolysis‐derived pyruvate conversion by lactate dehydrogenase (LDH) or direct cellular uptake via monocarboxylate transporters (MCTs). These L‐lactate pools fuel two distinct lactylation pathways—
Anoosha Malik +10 more
wiley +1 more source
Proliferation and differentiation of spermatogonial stem cells [PDF]
Reproduction, 2001 Abstract Spermatogonial stem cells (A(s) spermatogonia) are single cells that either renew themselves or produce A(pr) (paired) spermatogonia predestined to differentiate. In turn, the A(pr) divide into chains of A(al) (aligned) spermatogonia that also divide.
openaire +2 more sources