Results 11 to 20 of about 10,346 (209)
Spermatogonial stem cells: Progress and prospects [PDF]
Asian Journal of Andrology, 2015 Twenty years ago, the transplantation of spermatogonial stem cells (SSCs) from a mouse to other recipient mice was shown to be feasible, which clearly demonstrated the functional identity of SSCs.
Mitsuru Komeya, Takehiko Ogawa
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Culture and transplantation of spermatogonial stem cells [PDF]
Stem Cell Research, 2018 The spermatogonial transplantation technique was developed by Dr. Ralph Brinster in 1994. Transplanted spermatogonial stem cells (SSCs) produce germ cell colonies after microinjection into the seminiferous tubules of infertile mice.
Seiji Takashima, Takashi Shinohara
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Spermatogonial stem cells [PDF]
Current Opinion in Cell Biology, 1998 The mammalian seminiferous epithelium consists of a highly complex yet well-organized cell population, with germ cells in mitosis and meiosis and postmeiotic cells undergoing transformation to become spermatozoa. To study the factors which control renewal and differentiation of spermatogonial stem cells, animal models are now available which allow for ...
de rooij, D. G., Grootegoed, J. A.
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Plasticity of spermatogonial stem cells [PDF]
Asian Journal of Andrology, 2015 There have been significant breakthroughs over the past decade in the development and use of pluripotent stem cells as a potential source of cells for applications in regenerative medicine. It is likely that this methodology will begin to play an important role in human clinical medicine in the years to come. This review describes the plasticity of one
Paul S Cooke +4 more
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Fertility restoration with spermatogonial stem cells [PDF]
Current Opinion in Endocrinology, Diabetes & Obesity, 2017 Purpose of review This review evaluates the state of the art in terms of challenges and strategies used to restore fertility with spermatogonial stem cells retrieved from prepubertal boys affected by cancer. Although these boys do not yet produce spermatozoa, the only option to preserve their fertility is cryopreservation of ...
Francesca, de Michele +2 more
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Defining the spermatogonial stem cell [PDF]
Developmental Biology, 2004 Through the use of donor cells from transgenic rats expressing GFP exclusively in the germline, we have defined culture conditions where male germ cells lose (on STO cells) or maintain (on MSC-1 cells) stem cell activity. A cadre of germ cell transcripts strikingly decrease in relative abundance as a function of testis age or culture time on STO cells,
Kent Hamra, F. +6 more
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Cryopreserving and Thawing Spermatogonial Stem Cells [PDF]
Cold Spring Harbor Protocols, 2017 Spermatogonial stem cells (SSCs) can be cryopreserved and stored in liquid nitrogen, using relatively standard cryopreservation techniques. At a subsequent time, they can be thawed for subsequent culture and expansion and then transplanted to generate spermatogenesis.
Jon Oatley
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Melatonin improves spermatogonial stem cells transplantation efficiency in azoospermic mice [PDF]
Iranian Journal of Basic Medical Sciences, 2014 Objective(s):Transplantation quality improvement and reduction of cellular damage are important goals that are now considered by researchers. Melatonin is secreted from the pineal gland and some organs such as testes.
Mohammadreza Gholami +4 more
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Spermatogonial Stem Cells [PDF]
Avian Biology Research, 2011 Testicular gonocytes differentiate into spermatogonia, and spermatogonial stem cells could be established by culturing spermatogonia in vitro. Testicular and ovarian gonocytes were identified as relatively large cells in a population of gonadal cells.
Mitsuru Naito
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Spermatogonial stem cells as a source for regenerative medicine [PDF]
Middle East Fertility Society Journal, 2012 Several researchers have reported the derivation of multipotent cells from both mouse and human spermatogonial stem cells. These spermatogonia-derived stem cells show similarities with embryonic stem cells both for phenotype and functionality, indicating
Liang Ning +4 more
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