Spermatogonial Stem Cell Niche and Spermatogonial Stem Cell Transplantation in Zebrafish
Spermatogonial stem cells (SSCs) are the foundation of spermatogenesis, and reside within a specific microenvironment in the testes called "niche" which regulates stem cell properties, such as, self-renewal, pluripotency, quiescence and their ability to differentiate.Here, we introduce zebrafish as a new model for the study of SSCs in vertebrates ...
Nóbrega, Rafael Henrique +5 more
openaire +6 more sources
Propagation of Human Spermatogonial Stem Cells In Vitro [PDF]
Context Young boys treated with high-dose chemotherapy are often confronted with infertility once they reach adulthood. Cryopreserving testicular tissue before chemotherapy and autotransplantation of spermatogonial stem cells at a later stage could ...
Korver, Cindy M. +12 more
core +1 more source
Cellular Therapy via Spermatogonial Stem Cells for Treating Impaired Spermatogenesis, Non-Obstructive Azoospermia [PDF]
Male infertility is a major health problem affecting about 8–12% of couples worldwide. Spermatogenesis starts in the early fetus and completes after puberty, passing through different stages.
Jongki Cho +7 more
core +1 more source
A Generation of Mouse Spermatogonial Stem-Cell-Colonies in Non-adherent Culture
Objective: The properties of self-renewal and division in spermatogonial stem cells (SSCs) support spermatogenesis. There is a number of reported methods for in vitro SSC culture systems.
Hossein Azizi +2 more
doaj +1 more source
For decades, scientists have thought that female mammals are born with a lifetime supply of oocytes in the ovary, irreversibly destined to decline after birth.
Tomaszczuk-Kossowska, Katarzyna
core +1 more source
Regulation of the Spermatogonial Stem Cell Niche [PDF]
ContentsSpermatogonial stem cells (SSCs) reside within specialized microenvironments called ‘niches’, which are essential for their maintenance and self‐renewal. In the mammalian testis, the main components of the niche include the Sertoli cell, the growth factors that this nursing cell produces, the basement membrane, and stimuli from the vascular ...
N, Kostereva, M-C, Hofmann
openaire +2 more sources
Effects of Alkaline Phosphatase, GATA, and BMP Expression on Three Populations of Cells: Spermatogonial Stem Cells, Embryonic Cells, and Embryonic Stem-Like Cells in Mice [PDF]
Background and Objective: Alkaline phosphatase, BMP, and GATA proteins are important factors in the process of spermatogenesis. This study aims to investigate the effect of alkaline phosphatase, GATA, and BMP expression on spermatogenic stem cells ...
Emad Reza, Hossein Azizi
doaj
Three-Dimensional Culture of Mouse Spermatogonial Stem Cells Using A Decellularised Testicular Scaffold [PDF]
Objective: Applications of biological scaffolds for regenerative medicine are increasing. Such scaffolds improve cell attachment, migration, proliferation and differentiation. In the current study decellularised mouse whole testis was used as a natural
Nasrin Majidi Gharenaz +2 more
doaj +1 more source
Genetic and Epigenetic Evaluation of Human Spermatogonial Stem Cells Isolated by MACS in Different Two and Three-Dimensional Culture Systems [PDF]
Objective: Epigenetic and genetic changes have important roles in stem cell achievements. Accordingly, the aim of thisstudy is the evaluation of the epigenetic and genetic alterations of different culture systems, considering their efficacy inpropagating
Maria Zahiri +6 more
doaj +1 more source
Enrichment of Spermatogonial Stem Cells using Side Population in Teleost [PDF]
Spermatogenesis originates from a small population of spermatogonial stem cells; this population can maintain continuous sperm production throughout the life of fish via self-renewal and differentiation.
Yoshizaki, Goro +7 more
core +2 more sources

