Results 141 to 150 of about 77,896 (237)
Good nutrition in pregnancy and early life plays a key role in shaping the offspring gut microbiota, which supports healthy growth, immune maturation, and neurodevelopment. Poor maternal and early‐life diets can disrupt this process, increasing the risk of obesity, undernutrition, and disease later in life.
Fanette Fontaine +5 more
wiley +1 more source
The objectives of the review are the collection, concise description and evaluation of the various chromatographic techniques used for the separation and quantitative determination of macro- and microcomponents present in ...
Cserháti, Tibor, Szőgyi, Mária
core
Purification and characterization of recombinant human translation initiation factor eIF3
Abstract Eukaryotic translation initiation factor 3 (eIF3) is an essential factor in protein synthesis. In mammals, it is a ~800 kDa complex composed of 12–13 subunits. Biochemical and mechanistic studies of the function of eIF3 and its individual subunits in translation require purified eIF3.
Irene Diaz‐Lopez +4 more
wiley +1 more source
Mono- and Trivalent Ions around DNA: A Small-Angle Scattering Study of Competition and Interactions
The presence of small numbers of multivalent ions in DNA-containing solutions results in strong attractive forces between DNA strands. Despite the biological importance of this interaction, e.g., DNA condensation, its physical origin remains elusive ...
Andresen, Kurt +6 more
core
Harnessing DNA Binding Proteins from Starved Cells for DNA Origami Protection
E. coli Dps is electrostatically self‐assembled with DNA origami to yield highly ordered structures. The cooperative assembly of ordered structures depends on the size and shape of the DNA origami. Furthermore, the degree of order could be improved by increasing the buffer ionic strength.
Sharon Saarinen +6 more
wiley +1 more source
Spermidine reduces ISGylation and enhances ISG15–USP18 interaction
The expression of ubiquitin-like molecule interferon-stimulated gene 15 kDa (ISG15) and its post-translational modification (ISGylation) are significantly activated by interferons or pathogen infections, highlighting their roles in innate immune ...
Haruka Etori +3 more
doaj +1 more source
Novel gating mechanism of polyamine block in the strong inward rectifier K channel Kir2.1. [PDF]
Inward rectifying K channels are essential for maintaining resting membrane potential and regulating excitability in many cell types. Previous studies have attributed the rectification properties of strong inward rectifiers such as Kir2.1 to voltage ...
John, SA, Lee, JK, Weiss, JN
core +1 more source
Enhancer Rewiring Orchestrates Inflammation and Loss of Cell Identity During Muscle Stem Cell Aging
A comprehensive multi‐omic profiling of murine muscle stem cells across three ages and both sexes reveals extensive enhancer and 3D genome rewiring, concomitant with increased inflammation, lineage drift, loss of quiescence, and reduced myogenic potential.
Changyou Shi +17 more
wiley +1 more source
Human Umbilical Cord Plasma Metabolomics Uncover Potential Metabolites for Combating Aging
Untargeted metabolomics reveals a unique cord plasma metabolic landscape versus adult. Age‐declining cord‐specific enriched metabolites are identified as antiaging candidates, with a 5‐compound formula validated in proof‐of‐experiments to extend lifespan and healthspan in human cells and C. elegans.
JiaYu Liu +27 more
wiley +1 more source

