Results 61 to 70 of about 47,051 (228)

Bacterial infection reinforces host metabolic flux from arginine to spermine for NLRP3 inflammasome evasion

open access: yesCell Reports, 2021
Summary: Hosts recognize cytosolic microbial infection via the nucleotide-binding domain-like receptor (NLR) protein family, triggering inflammasome complex assembly to provoke pyroptosis or cytokine-related caspase-1-dependent antimicrobial responses ...
Jiatiao Jiang   +5 more
doaj   +1 more source

Antimycotic Effect of Spermine.

open access: yesExperimental Biology and Medicine, 1958
Summary1) Spermine inhibited growth of several species of yeasts, Saccharomyces and Debaryomyces species being the most sensitive. The antimycotic effect of spermine was more pronounced at an alkaline pH and was antagonized by inorganic salts. The adsorption of spermine by yeast cells was significantly smaller than by Staph. aureus.
S, RAZIN, A, COHEN, R, ROZANSKY
openaire   +2 more sources

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

open access: yesBMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao   +4 more
wiley   +1 more source

Monitoring and Mitigation Strategies for Hazardous Compounds in Chinese Rice Wine (Huangjiu): A Comprehensive Review

open access: yesFood Safety and Health, EarlyView.
This review elucidates the formation pathways and detection technologies for ethyl carbamate, biogenic amines, and higher alcohols in Huangjiu. It concludes that integrated control frameworks are essential to decouple safety risks from the metabolic processes responsible for flavor development.
Lulu Liu   +5 more
wiley   +1 more source

The Development of Polyamines throughout Brassica rapa over its Lifecycle [PDF]

open access: yes, 2014
Polyamines are naturally produced chemicals in plants involved in growth, development and stress response. The primary objective of my study is to create a profile of changes in the entire life of the plant, in every organ at all stages of development ...
Larsen, Jon   +2 more
core   +1 more source

Nephrotoxic Action of Spermine

open access: yesExperimental Biology and Medicine, 1952
ConclusionsSpermine administered parenterally is highly active in producing renal injury in mice, rats, and rabbits. This property was not observed for spermidine, putrescine, or cadaverine.
S M, ROSENTHAL   +2 more
openaire   +2 more sources

β‐Aminoisobutyric Acid Alleviates Cisplatin‐Induced Muscle Atrophy by Regulating E3 Ubiquitin Ligases, Apoptosis, Amino Acid Metabolism, Autophagy, and Ferroptosis

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT Background Cisplatin (CIS) is a widely used broad‐spectrum anticancer agent, but its clinical application is often limited by severe adverse effects, including skeletal muscle atrophy, which compromises patients' quality of life and treatment efficacy.
Hao‐Zhe Wang   +10 more
wiley   +1 more source

Difluoromethylornithine rebalances aberrant polyamine ratios in Snyder–Robinson syndrome

open access: yesEMBO Molecular Medicine, 2023
Snyder–Robinson syndrome (SRS) results from mutations in spermine synthase (SMS), which converts the polyamine spermidine into spermine. Affecting primarily males, common manifestations of SRS include intellectual disability, osteoporosis, hypotonia, and
Tracy Murray Stewart   +8 more
doaj   +1 more source

Nickel Foam Electrodes—A Versatile, Powerful, and Readily Available Tool in Electro‐Organic Synthesis

open access: yesThe Chemical Record, EarlyView.
Nickel foam—one material, two faces, and several versatile roles depending on electrolytic conditions. For more than 50 years, nickel foam electrodes have served in electrosynthesis as powerful and readily available electrode materials. Due to their inexpensive nature and easy handling, they have been widely employed.
Rok Narobe   +2 more
wiley   +1 more source

Growth regulatory effects of cyclic AMP and polyamine depletion are dissociable in cultured mouse lymphoma cells. [PDF]

open access: yes, 1983
Treatment of mouse lymphoma S49 cells with D,L-alpha-difluoromethylornithine (DFMO), an inhibitor of ornithine decarboxylase, depleted cellular polyamine levels and stopped cell growth. The cells were arrested predominantly in G1.
Coffino, P, Marton, LJ, McConlogue, LC
core  

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