Results 51 to 60 of about 30,707 (232)

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Spermine

, 2002
Inelastic Neutron Scattering spectrum of Spermine, H₂N(CH₂)₃NH(CH₂)₄NH(CH₂)₃NH₂, measured on the TOSCA ...
M. P. M. Marques, Universidade de Coimbra, Portugal
core   +1 more source

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source

Nap-spermine, an agonist of spermine receptor TAAR348, induced responses virtually identical to those induced by spermine.

, 2019
(A) Nap-spermine induced cAMP production in a concentration-dependent manner in TAAR348-expressing HEK293T cells (mean ± SEM, n = 5). The cAMP assay was done as in Fig 3B. (Inset) Structure of nap-spermine. (B) EOG responses to 10−7 M spermine and 10−7 M
Edmund Ellsworth (6934163), Richard R. Neubig (234327), Thomas Dexheimer (6191585), Jianfeng Ren (3277365), Yao Zu (6934166), Ke Li (106849), Yu-Wen Chung-Davidson (1688224), Liang Jia (212225), Qinghua Zhang (145923), Zhe Zhang (81603), Weiming Li (126966), Anne M. Scott (4371052)   +11 more
core   +1 more source

Effects of spermine on immune organ indexes and expression levels of genes related to immune factors in geese

浙江大学学报. 农业与生命科学版, 2019
To investigate the effects of spermine on goose immune organ indexes and expression levels of genes related to immune factors, the Sichuan adult white geese (female) were intragastrically administered with 5 and 10 mg spermine per kilogram body mass, and
YI Zhixin, JIANG Yilong, WANG Qiuhong, XU Qilin, WANG Xinxing, MO Guilin, JIANG Dongmei, KANG Bo   +7 more
doaj   +1 more source

Monitoring and Mitigation Strategies for Hazardous Compounds in Chinese Rice Wine (Huangjiu): A Comprehensive Review

Food Safety and Health, EarlyView.
This review elucidates the formation pathways and detection technologies for ethyl carbamate, biogenic amines, and higher alcohols in Huangjiu. It concludes that integrated control frameworks are essential to decouple safety risks from the metabolic processes responsible for flavor development.
Lulu Liu, Zhiqiang Kong, Lin Li, Yifan Zhang, Bei Fan, Minmin Li   +5 more
wiley   +1 more source

N1-dansyl-spermine: a potent polyamine antagonist.

, 2004
The potential polyamine antagonist action of N1-dansyl-spermine (a potent NMDA antagonist) was assessed in two in vivo mouse models of polyamine action. Co-administration of N1-dansyl-spermine (2?10 ?g, i.c.v.) with spermine (100 ?g, i.c.v.) resulted in ...
RYDER, SHEILA
core   +1 more source

Spermine and L-name pretreatment effects on polyamine and nitric oxide metabolism in rat brain during seizures [PDF]

Journal of Medical Biochemistry, 2007
In the CNS polyamines can exert opposite effects, depending on the concentration and conditions in the cell. Protective or neurotoxic polyamine effects were documented during seizures and repeated CNS excitation.
Stojanović Ivana, Jelenković Ankica, Vasiljević Ivana, Pavlović Dušica, Bjelaković Gordana   +4 more
doaj  

β‐Aminoisobutyric Acid Alleviates Cisplatin‐Induced Muscle Atrophy by Regulating E3 Ubiquitin Ligases, Apoptosis, Amino Acid Metabolism, Autophagy, and Ferroptosis

Medicine Bulletin, EarlyView.
ABSTRACT Background Cisplatin (CIS) is a widely used broad‐spectrum anticancer agent, but its clinical application is often limited by severe adverse effects, including skeletal muscle atrophy, which compromises patients' quality of life and treatment efficacy.
Hao‐Zhe Wang, Wen‐Bi He, Huan Wang, Hao Wang, Wen‐Jun Fang, Meng‐Qian Li, Jiong‐Xing Huang, Fei‐Peng Chen, Hui‐Guo Wang, Lin Zhu, Xiao‐Guang Liu   +10 more
wiley   +1 more source

Spermine induces cataract and 43-kDa protein that binds spermine possibly participates in the cataract formation

, 2003
Among polyamines (putrescine, spermidine, and spermine), spermine specifically induces cataract in an organ cultured lens. Spermine uptake nearly paralleled the cataract formation.
Kunio Nakashima, Satoru Maekawa, Moto Kataoka, Uji, Yukitaka, Kataoka, Moto, Nakashima, Kunio, Hiroshige Hibasami, Hibasami, Hiroshige, Maekawa, Satoru, Yukitaka Uji   +9 more
core   +1 more source