Results 31 to 40 of about 34,064 (250)
Spermine-Based Poly(β-amino ester)s for siRNA Delivery against Mutated KRAS in Lung Cancer
, 2023 Polyethylenimine (PEI) is a highly efficient cationic polymer for nucleic acid delivery, and although it is commonly used in preclinical studies, its clinical application is limited because of concerns regarding its cytotoxicity. Poly(β-amino ester)s are
Lorenz Isert (16826940) +9 more
core +1 more source
PLoS ONE, 2013 Spermine oxidase is a FAD-containing enzyme involved in polyamines catabolism, selectively oxidizing spermine to produce H2O2, spermidine, and 3-aminopropanal. Spermine oxidase is highly expressed in the mouse brain and plays a key role in regulating the
Manuela Cervelli +12 more
doaj +1 more source
Metabolism of N-alkylated spermine analogues by polyamine and spermine oxidases [PDF]
Amino Acids, 2009 N-alkylated polyamine analogues have potential as anticancer and antiparasitic drugs. However, their metabolism in the host has remained incompletely defined thus potentially limiting their utility. Here, we have studied the degradation of three different spermine analogues N,N'-bis-(3-ethylaminopropyl)butane-1,4-diamine (DESPM), N-(3-benzyl ...
Merja R, Häkkinen +7 more
openaire +2 more sources
Кібернетика та комп'ютерні технології, 2023 Introduction. One of the main areas of application of SPR sensors is biochemical analysis. The "Plasmontest" device, developed at the Institute of Cybernetics of the National Academy of Sciences of Ukraine, was used for rapid diagnosis of various ...
Tetyana Lebyedyeva +5 more
doaj +1 more source
Improving Chilling Tolerance of Maize Seedlings under Cold Conditions by Spermine Application
Notulae Scientia Biologicae, 2012 Low temperature is an important abiotic stress which reduces crops growth and productivity and causes physiological damages to cellular structures. The aim of this study was to investigate the probability of spermine application to improve chilling ...
Amir Hossein SAEIDNEJAD +2 more
doaj +3 more sources
SPERMINE OXIDASE: AN AMINE OXIDASE WITH SPECIFICITY FOR SPERMINE AND SPERMIDINE [PDF]
Journal of Experimental Medicine, 1953 Sheep serum and bovine serum contain an enzyme which brings about a rapid oxidative deamination of certain biological amines. This enzyme differs from previously described amine oxidases in several regards and especially in its substrate specificity.
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Journal of BacteriologyMycobacterium tuberculosis is well adapted to survive and persist in the infected host, escaping the host’s immune response. Since polyamines such as spermine, which are synthesized by infected macrophages, are able to inhibit the growth of M ...
Sergii Krysenko +14 more
doaj +1 more source
Antimycotic Effect of Spermine.
Experimental Biology and Medicine, 1958 Summary1) Spermine inhibited growth of several species of yeasts, Saccharomyces and Debaryomyces species being the most sensitive. The antimycotic effect of spermine was more pronounced at an alkaline pH and was antagonized by inorganic salts. The adsorption of spermine by yeast cells was significantly smaller than by Staph. aureus.
S, RAZIN, A, COHEN, R, ROZANSKY
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Food Production, Processing and Nutrition, 2020 1H NMR spectroscopy was adopted to determine compositional changes (mainly sugars, organic acids and amino acids) involved in cold-stored immature soybean grains after exogenous spermine treatment.
Jiangfeng Song +4 more
doaj +1 more source