Results 21 to 30 of about 41,546 (228)
Spermidine and spermine delay brain aging by inducing autophagy in SAMP8 mice
Aging, 2020 The natural polyamine spermidine and spermine have been reported to ameliorate aging and aging-induced dementia. However, the mechanism is still confused. An aging model, the senescence accelerated mouse-8 (SAMP8), was used in this study.
Tingting Xu +11 more
semanticscholar +1 more source
The Emerging Clinical Role of Spermine in Prostate Cancer
International Journal of Molecular Sciences, 2021 Spermine, a member of polyamines, exists in all organisms and is essential for normal cell growth and function. It is highly expressed in the prostate compared with other organs and is detectable in urine, tissue, expressed prostatic secretions, and ...
Qiang Peng +5 more
semanticscholar +1 more source
Nature Communications, 2020 Dysregulation of polyamine metabolism has been linked to the development of colorectal cancer (CRC), but the underlying mechanism is incompletely characterized.
Yubin Guo +14 more
semanticscholar +1 more source
L-ornithine derived polyamines in cystic fibrosis airways. [PDF]
PLoS ONE, 2012 Increased arginase activity contributes to airway nitric oxide (NO) deficiency in cystic fibrosis (CF). Whether down-stream products of arginase activity contribute to CF lung disease is currently unknown.
Hartmut Grasemann +5 more
doaj +1 more source
Effects of dietary spermine supplementation on cell cycle, apoptosis, and amino acid transporters of the thymus and spleen in piglets [PDF]
Asian-Australasian Journal of Animal Sciences, 2018 Objective This study investigated whether spermine supplementation could regulate cell cycle, apoptosis, and amino acid transporter-related genes expression in the thymus and spleen of early weaned piglets.
Wei Cao +8 more
doaj +1 more source
Animal Nutrition, 2016 The main objective of this study was to investigate the effects of different doses of spermine and its extended supplementation on the morphology, digestive enzyme activities, and intestinal antioxidant capacity in weaning rats.
Tingting Fang +6 more
doaj +1 more source
The polyamine spermine induces the unfolded protein response via the MAPK cascade in Arabidopsis
Frontiers in Plant Science, 2015 In Arabidopsis three basic region leucine zipper (bZIP) transcription factor genes, bZIP17, bZIP28 and bZIP60, play crucial roles in the unfolded protein response (UPR). Previously we found that bZIP60 is one of the spermine-induces genes.
G.H.M. eSagor +6 more
doaj +1 more source
PLoS ONE, 2013 Spermine oxidase is a FAD-containing enzyme involved in polyamines catabolism, selectively oxidizing spermine to produce H2O2, spermidine, and 3-aminopropanal. Spermine oxidase is highly expressed in the mouse brain and plays a key role in regulating the
Manuela Cervelli +12 more
doaj +1 more source
Кібернетика та комп'ютерні технології, 2023 Introduction. One of the main areas of application of SPR sensors is biochemical analysis. The "Plasmontest" device, developed at the Institute of Cybernetics of the National Academy of Sciences of Ukraine, was used for rapid diagnosis of various ...
Tetyana Lebyedyeva +5 more
doaj +1 more source