Results 111 to 120 of about 8,836 (207)

The low intestinal and hepatic toxicity of hydrolyzed fumonisin B1 correlates with its inability to alter the metabolism of sphingolipids [PDF]

, 2012
Fumonisins are mycotoxins frequently found as natural contaminants in maize, where they are produced by the plant pathogen Fusarium verticillioides. They are toxic to animals and exert their effects through mechanisms involving disruption of sphingolipid
Trumel, Catherine, Schatzmayr, Gerd, Loureiro-Bracarense, Ana-Paula, Cossalter, Anne-Marie, Oswald, Isabelle P., Cossalter, Anne Marie, Grenier, Bertrand, Moll, Wulf-Dieter, Oswald, Isabelle P, Schwartz, Heidi-Elisabeth, Kolf-Clauw, Martine, Schwartz, Heidi Elisabeth, Bracarense, Ana-Paula   +12 more
core   +1 more source

Integrative transcriptomics–metabolomics reveals sphingolipid metabolic reprogramming in traditional Chinese medicine syndrome differentiation of rheumatoid arthritis

Frontiers in Immunology
ObjectiveTo investigate sphingolipid metabolism for differentiating heat-dampness syndrome from kidney-liver deficiency syndrome in Rheumatoid Arthritis (RA), identify metabolic biomarkers, and integrate transcriptomic data to elucidate molecular ...
Yao Li, Yao Li, Yao Li, Yao Li, Ying Wu, Ying Wu, JinXiang Zeng, JinXiang Zeng, Xueyan Guo, Xueyan Guo, Xueyan Guo, Weifeng Lv, Weifeng Lv, Weifeng Lv, JunWei Lin, JunWei Lin, JunWei Lin, Kun Lin, Kun Lin, Qihong Guo, Qihong Guo, Rong Su, Rong Su, Rong Su   +23 more
doaj   +1 more source

Oat bran ameliorated DSS-induced mice colitis by suppressing inflammation and enriching beneficial metabolites derived from gut microbiota

Journal of Agriculture and Food Research
Inflammatory bowel disease (IBD) is characterized by chronic gastrointestinal inflammation and gut microbiota dysbiosis. This study evaluated the protective effects of cooked oat bran (COB) on dextran sulfate sodium (DSS)-induced colitis in mice.
Qixin Gu, Ying Miao, Haoyuan Ma, Meili Zhang   +3 more
doaj   +1 more source

The effect of repeated gavage doses of fumonisin B 1 on the sphinganine and sphingosine levels in vervet monkeys

, 2001
Fumonisins occur widely around the world in maize products intended for human and animal consumption posing a health hazard. Direct measurement of fumonisins in physiological fluids as a biomarker of exposure is not practicable, however fumonisins ...
Shepherd, G.S, D.J. van Schalkwyk, Van Schalkwyk, Dirk J, Van der Westhuizen, Liana, L. van der Westhuizen, G.S. Shephard   +5 more
core   +1 more source

Masthead: (View 4/2026)

VIEW, Volume 7, Issue 4, August 2026.
wiley   +1 more source

Optimized Lipidomics Extraction of Sphingosine and Sphinganine from Optic Nerve for Signaling Studies

Interconvertible sphingolipid metabolites represent germane constituents of eukaryotic membranes and are vital in the regulation of cellular homeostasis, proliferation, survival, and induction of autophagy.
Jauregui, Alexa, Neag, Emily J, Almobayed, Amr, Bhattacharya, Sanjoy K, Lens, Alexandra   +4 more
core   +1 more source

Sphinganine and sphinganine to sphingosine ratio as a biomarker of dietary fumonisins during chronic exposure in ducks.

, 2006
International audienceFumonisin B1 is structurally similar to sphinganine (Sa) and sphingosine (So) and inhibits ceramide synthase. It causes an elevation in Sa concentration, leading to an increase in Sa/So ratio in exposed animals.
Tardieu, Delphine, Babile, René, Auvergne, Alain, Guerre, P., Bailly, J.D.   +4 more
core   +2 more sources

MPK6, sphinganine and the \u3ci\u3eLCB2a\u3c/i\u3e gene from serine palmitoyltransferase are required in the signaling pathway that mediates cell death induced by long chain bases in \u3ci\u3eArabidopsis\u3c/i\u3e [PDF]

, 2011
• Long chain bases (LCBs) are sphingolipid intermediates acting as second messengers in programmed cell death (PCD) in plants. Most of the molecular and cellular features of this signaling function remain unknown.
Ramos-Vega, Maricela, Gonzalez-Solis, Ariadna, Gavilanes-Ruiz, Marina, Markham, Jennifer E., Markham, Jonathan E., Cruz-Garcia, Felipe, Dietrich, Charles R., Vazquez-Santana, Sonia, Cahoon, Edgar B., Guevara-Garcia, Arturo, Saucedo-Garcia, Mariana, Lozano-Rosas, M. Guadalupe   +11 more
core  

Fumonisins and \u3ci\u3eAlternaria alternata\u3c/i\u3e lycopersici toxins: Sphinganine analog mycotoxins induce apoptosis in monkey kidney cells [PDF]

, 1996
Fusarium moniliforme toxins (fumonisins) and Alternaria alternata lycopersici (AAL) toxins are members of a new class of sphinganine analog mycotoxins that occur widely in the food chain.
Jones, Clinton, Caiacci-Zanella, Janice, Wang, Hong, Gilchrist, David G., Dickman, Martin B., Holt, Todd   +5 more
core  

Analysis of Sphingosine and Sphinganine from the Aqueous Humor for Signaling Studies Using Ultrahigh-Performance Liquid Chromatography-Mass Spectrometry

Sphingolipids, including sphingosine and sphinganine, are one of the major classes of lipids. They serve as constituents of cell membranes and lipid rafts and aid in the performance of cell-cell communication and adhesion.
Saleem, Meher A, Kennedy, Molly, Badla, Omar, Neag, Emily J, Bhattacharya, Sanjoy K   +4 more
core   +1 more source