Results 91 to 100 of about 8,836 (207)

Functionally complementary bacterial inoculant coordinates arbuscular mycorrhizal fungi to improve Angelica sinensis root yield and quality

iMetaOmics, Volume 3, Issue 2, June 2026.
Comprehensive understanding of how diverse PGPR strains enhance the rhizosphere microenvironment remains a considerable challenge. Here, we provide experimental evidence that a functionally synergistic composite microbial formulation can markedly enhance growth performance and improve the quality attributes in Angelica sinensis.
Zongyu Zhang, Yun Wang, Jiecai Zhao, Gaofeng Chen, Andéole Niyongabo Turatsinze, Liang Yue, Yuan Tian, Xiaofan Xie, Ailing Ye, Meilan Zhang, Lingling Wu, Zengxiang Guo, Yubao Zhang, Ruoyu Wang   +13 more
wiley   +1 more source

Trifunctional Sphinganine: A New Tool to Dissect Sphingolipid Function

Functions and cell biology of the sphingolipids sphingosine and sphinganine in cells are not well understood. While some signaling roles for sphingosine have been elucidated, the closely related sphinganine has been described only insofar as it does not ...
Frank Stein (1433122), Per Haberkant (752427), Carsten Schultz (141815), Fikadu G. Tafesse (11927557), Scotland Farley (11927554)   +4 more
core   +1 more source

Liquid chromatographic determination of the sphinganine/sphingosine ratio in serum

, 1998
ArticleThe fumonisin mycotoxins, which are worldwide contaminants of corn, inhibit de novo sphingolipid biosynthesis leading to elevation in the ratio of the sphingoid bases, sphinganine and sphingosine, in the serum of animals exposed to fumonisins.
van der Westhuizen, L, G.S Shephard, Shephard, Gordon Seymour, Van der Westhuizen, Liana, Shephard, GS, L van der Westhuizen   +5 more
core   +1 more source

Sphingolipid distribution at mitochondria-associated membranes (MAMs) upon induction of apoptosis[S]

Journal of Lipid Research, 2020
The levels and composition of sphingolipids and related metabolites are altered in aging and in common disorders such as diabetes and cancers, as well as in neurodegenerative, cardiovascular, and respiratory diseases.
Vincent Mignard, Nolwenn Dubois, Didier Lanoé, Marie-Pierre Joalland, Lisa Oliver, Claire Pecqueur, Dominique Heymann, François Paris, François M. Vallette, Lisenn Lalier   +9 more
doaj   +1 more source

Plasma Lipidomics of HIV-1 infected patients based on ultra performance liquid chromatography–mass spectrometry

Results in Chemistry
Acquired immune deficiency syndrome (AIDS) has been shown to not only attack the body's immune system but also to cause metabolic disorders. Highly active anti-retroviral therapy (HAART) is the main treatment for AIDS, but it can also affect the human ...
Aoxin Ma, Zhaobo Wu, Guojun Li, Xinyu Zhang, Xiangyun Tang, Shuofan Dong, Xinli Lu, Kaoqi Lian   +7 more
doaj   +1 more source

Inhibition of phorbol ester-dependent differentiation of human promyelocytic leukemic (HL-60) cells by sphinganine and other long-chain bases.

Journal of Biological Chemistry, 1986
The effects of long-chain (sphingoid) bases on the phorbol ester-dependent differentiation of HL-60 cells were investigated since these molecules are potent inhibitors of protein kinase C (Hannun, Y. A., Loomis, C. R., Merrill, A. H., Jr., and Bell, R. M.
Alfred H. Merrill, A. Sereni, Victoria L. Stevens, Y. A. Hannun, Robert M. Bell, Joseph M. Kinkade   +5 more
semanticscholar   +1 more source

Sptlc2-derived sphinganine is indispensable for inflammatory TLR4 signaling in macrophages [PDF]

Macrophages are key players in initiating, regulating, and driving inflammation, which, depending on the intensity and duration, can be extremely helpful or harmful during immune responses. A major pathway in macrophages driving inflammatory signaling is
Hering, Marvin
core   +1 more source

Elevation of sphinganine 1-phosphate as a predictive biomarker for fumonisin exposure and toxicity in mice

, 2018
Fumonisins are specific inhibitors of ceramide synthase in sphingolipid metabolism. An alteration in sphingolipid metabolism as a result of fumonisin B1 (FB1) exposure is related to cell death, and sphinganine/sphingosine ratio has been used as an ...
오세관
core   +1 more source

Activity of 3-ketosphinganine synthase during differentiation and aging of neuronal cells in culture

Journal of Lipid Research, 1997
Changes in the enzyme 3-ketosphinganine synthase activity in rat cerebellar granule cells in culture were studied during differentiation and aging. The enzyme activity with palmitoyl-CoA and stearoyl-CoA, precursors of, respectively, C18-sphinganine and ...
V Chigorno, E Negroni, M Nicolini, S Sonnino   +3 more
doaj   +1 more source

Asymmetric synthesis of vicinal amino alcohols: xestoaminol C, sphinganine and sphingosine.

, 2008
The highly diastereoselective anti-aminohydroxylation of alpha,beta-unsaturated esters, via conjugate addition of lithium (S)-N-benzyl-N-(alpha-methylbenzyl)amide and subsequent in situ enolate oxidation with (+)-(camphorsulfonyl)oxaziridine, has been ...
Smith, AD, Roberts, PM, Roberts, Paul M., Millican, Nicholas L., Davies, SG, Smith, Andrew D., Abraham, Elin, Abraham, E, Millican, NL, Nicholson, RL, Nicholson, Rebecca L., Davies, Stephen G., Davies, Stephen   +12 more
core   +1 more source