Results 71 to 80 of about 9,200 (222)
Liver International, Volume 46, Issue 3, March 2026.ABSTRACT Background and Aims Metabolic dysfunction‐associated steatotic liver disease (MASLD), the most common chronic liver disease worldwide, is closely linked to obesity and metabolic syndrome. The reason some patients with MASLD develop metabolic dysfunction‐associated steatohepatitis (MASH) and which metabolic changes in the liver are linked to ...
Saana Palomurto +14 more
wiley +1 more source
A rapid ceramide synthase activity using NBD-sphinganine and solid phase extraction
Journal of Lipid Research, 2015 Ceramides are synthesized by six mammalian ceramide synthases (CerSs), each of which uses fatty acyl-CoAs of different chain lengths for N-acylation of the sphingoid long-chain base. We now describe a rapid and reliable CerS assay that uses a fluorescent
Rotem Tidhar +4 more
doaj +1 more source
Glucose Reaction with Fumonisin B1 Partially Reduces Its Toxicity in Swine [PDF]
, 2004 Acute and subacute intraperitoneal doses of fumonisin B1 (FB1) were administered to test the efficacy of the FB1-glucose reaction products in detoxifying FB1 in swine.
Fernandez-Surumay, Guillermo +6 more
core +3 more sources
Pediatric Dermatology, Volume 43, Issue 2, Page 237-250, March/April 2026.ABSTRACT Background/Objective Growing evidence highlights the role of physiological lipids, namely ceramides, cholesterol, and free fatty acids, in maintaining skin barrier function and preventing atopic dermatitis (AD). Current evidence on the efficacy, safety, and clinical relevance of stratum corneum (SC) lipid‐based therapies to prevent AD and ...
Chon‐Wai Jeremy Chan +1 more
wiley +1 more source
Metabolic profiles in community-acquired pneumonia: developing assessment tools for disease severity
Critical Care, 2018 Background This study aimed to determine whether community-acquired pneumonia (CAP) had a metabolic profile and whether this profile can be used for disease severity assessment.
Pu Ning +13 more
doaj +1 more source
Lipids in Health and Disease, 2023 Background Stroke is the leading cause of death in humans worldwide, and its incidence increases every year. It is well documented that lipids are closely related to stroke.
Keqi Zeng +4 more
doaj +1 more source
New Approaches to Oxirane Containing Natural Products: Stereoselective Total Synthesis of the Antitumor Agents Gummiferol and Depudecin [PDF]
, 2015 La comunicación presenta la síntesis total de productos naturales con actividad antitumoral caracterizados estructuralmente por la presencia de anillos de oxirano.
García-Ruiz, Cristina +1 more
core
Essential requirement for sphingosine kinase activity in eNOS-dependent NO release and vasorelaxation [PDF]
, 2006 Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid that acts both as an extracellular ligand for endothelial differentiation gene receptor family and as an intracellular second messenger.
Brancaleone, V +9 more
core +1 more source
Reactive oxygen species as transducers of sphinganine-mediated cell death pathway [PDF]
Plant Signaling & Behavior, 2011 Long chain bases or sphingoid bases are building blocks of complex sphingolipids that display a signaling role in programmed cell death in plants. So far, the type of programmed cell death in which these signaling lipids have been demonstrated to participate is the cell death that occurs in plant immunity, known as the hypersensitive response.
Mariana, Saucedo-García +6 more
openaire +2 more sources
BMC Medical Genomics, 2023 Background Individuals with sepsis exhibited a higher likelihood of benefiting from early initiation of specialized treatment to enhance the prognosis of the condition. The objective of this study is to identify potential biomarkers of sepsis by means of
Jinliang Peng +3 more
doaj +1 more source