Results 61 to 70 of about 9,200 (222)

Inhibition of de novo ceramide biosynthesis affects aging phenotype in an in vitro model of neuronal senescence. [PDF]

open access: yes, 2019
Although aging is considered to be an unavoidable event, recent experimental evidence suggests that the process can be counteracted. Intracellular calcium (Ca2+i) dyshomeostasis, mitochondrial dysfunction, oxidative stress, and lipid dysregulation are ...
Bomba, Manuela   +12 more
core  

Sphingolipids as emerging mediators in retina degeneration [PDF]

open access: yes, 2019
The sphingolipids ceramide (Cer), sphingosine-1-phosphate (S1P), sphingosine (Sph), and ceramide-1-phosphate (C1P) are key signaling molecules that regulate major cellular functions.
Prado Spalm, Facundo Heber   +3 more
core   +1 more source

Honey as a Natural Flavorful Product: A Comprehensive Review of Its Potential Biological Activities and Recent Studies

open access: yesFood Science &Nutrition, Volume 14, Issue 4, April 2026.
Health impacts of honey. ABSTRACT Honey is a natural and nutritious product of the honey bee (Apis mellifera) with low water content. Its color ranges from white to amber, with taste varying accordingly. The chemical form and viscosity of honey depend on its composition.
Ecem Bolat   +7 more
wiley   +1 more source

Effect of the multifunctional cosmetic ingredient sphinganine on hair loss in men and women with diffuse hair reduction

open access: yesClinical, Cosmetic and Investigational Dermatology, 2016
Nicole Gerlach,1,* Matthias Mentel,2,* Tim Köhler,2 Benjamin Tuchscherer,2 Birgit Garbe,1 Jasmina Ülker,1 Hagen Tronnier,1 Ulrike Heinrich,1 Mike Farwick2 1DermaTronnier GmbH & Co. KG, Institute for Experimental Dermatology, Witten/Herdecke
Gerlach N   +8 more
doaj  

Dihydromyricetin Regulates PANoptosis to Protect Salmonella Typhimurium‐Infected Weaned Piglets

open access: yesFood Frontiers, Volume 7, Issue 2, March 2026.
After DHM pretreatment, piglets were subjected to Salmonella infection. Serum and ileocecal samples from the piglets were collected for TUNEL assay, Western blotting analysis, and metabolomics analysis. The results collectively indicated that DHM could protect piglets from Salmonella infection.
Tingting Xiao   +6 more
wiley   +1 more source

Rabbit muscle gangliosides

open access: yesJournal of Lipid Research, 1972
Four ganglioside fractions were isolated from rabbit muscle : one hematoside and three hexosamine-containing species. They were analyzed for hexoses, hexosamine, sialic acid, fatty acids, and long-chain base content.
F.E. Lassaga   +2 more
doaj   +1 more source

Changes in Plasma Sphingolipid Metabolites Following Roux‐En‐Y Gastric Bypass in Women With Obesity and Type 2 Diabetes: A Pilot Metabolomic Cohort Study

open access: yesLipids, Volume 61, Issue 2, Page 195-205, March 2026.
ABSTRACT Although sphingolipids are key players in lipotoxicity and metabolic diseases, their response to bariatric surgery and their relation to metabolic improvement remain unclear. This pilot study investigated plasma sphingolipid remodeling after Roux‐en‐Y gastric bypass (RYGB) and its associations with clinical and biochemical markers of ...
Gabriela de Oliveira Lemos   +3 more
wiley   +1 more source

Production and purification of fumonisins from a highly toxigenic Fusarium verticilloides strain [PDF]

open access: yes, 2005
Fumonisins are the major mycotoxins produced by Fusarium verticilloides and F. proliferatum fungi which are widely found as contaminants in corn and corn screenings.
Bailly, Jean Denis   +3 more
core  

Fenretinide induces lethal autophagy via a novel ensemble of life and death regulators: dihydroceramide and sphinganine versus sphinganine 1‐phosphate.

open access: yesThe FASEB Journal, 2007
Fenretinide (4‐hydroxyphenylretinamide, 4HPR) is a promising anticancer agent that is being evaluated in human clinical trials. One of the proposed mechanisms of action for fenretinide is to increase the biosynthesis of ceramide, an inducer of apoptosis. Using LC ESI MS/MS for “sphingolipidomic” analysis of MCF7 cells, we find that fenretinide elevates
Kacee Sims   +11 more
openaire   +1 more source

Impact of Ceramide Acyl Chain Length on Human Skin Barrier Recovery and Hydration

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 3, March 2026.
ABSTRACT Objective To compare the effects of ceramide acyl chain length on human skin barrier function. Methods Mixtures of phytoceramide containing non‐hydroxy fatty acids (CER NPs) with different acyl chain lengths and corresponding test creams were prepared: C16–C24 CER NP and C24–C30 CER NP (ultra‐long‐chain, ULC CER NP).
Do‐Hyeon Gwon   +6 more
wiley   +1 more source

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