Results 191 to 200 of about 68,956 (338)

The serine palmitoyl transferase of plant pathogenic fungi: a promising new target for the development of novel crop protection solutions†

open access: yesPest Management Science, EarlyView.
High biological activity of pyridazine carboxamides against a wide range of Ascomycetes led to identification of a new biochemical target for agrochemical fungicides – serine palmitoyl transferase. Abstract BACKGROUND Plant pathogens pose a significant threat to global agriculture and, thus to world food supplies, requiring the development of ...
Lionel Nicolas   +13 more
wiley   +1 more source

Molecular Maestro in the Lung: The Sphingolipid Rheostat. [PDF]

open access: yesAm J Respir Cell Mol Biol
Rojas-Quintero J, Polverino F.
europepmc   +1 more source

Mathematical Modeling of Neuroinflammation in Neurodegenerative Diseases

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Age‐related neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), Alzheimer's disease (AD) and Parkinson's disease (PD) are an increasing public health concern. Whereas the pathology of these diseases is complex, chronic central inflammation, or neuroinflammation, is commonly observed across many neurodegenerative diseases ...
Alex Foster‐Powell   +4 more
wiley   +1 more source

Editorial: Sphingolipid metabolism dysfunction in cancer

open access: yesFrontiers in Endocrinology, 2023
Rashika El Ridi   +2 more
doaj   +1 more source

Advances in ORMDL Research in Malignant Tumors: A Review. [PDF]

open access: yesOnco Targets Ther
Wang H   +10 more
europepmc   +1 more source

Synthesis of Mannose-(inositol-P)2-ceramide, the Major Sphingolipid in Saccharomyces cerevisiae, Requires the IPT1 (YDR072c) Gene [PDF]

open access: hybrid, 1997
Robert C. Dickson   +4 more
openalex   +1 more source

Understanding of endo/lysosomal escape of nanomaterials in biomedical application

open access: yesSmart Molecules, EarlyView.
This review summarized mainstream mechanisms of endo/lysosomal escape and design strategies of endo/lysosomal escapable nanoparticles in view of surface charge, polarity & hydrophobicity, particle morphology, and lysosomal escape agents. The utilization of endo/lysosomal escapable nanoparticles for vaccine delivery and genetic engineering are ...
Xin Wang   +3 more
wiley   +1 more source

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