Results 121 to 130 of about 52,176 (275)

Proteomic profiling of porcine seminal extracellular vesicles reveals potential in vivo fertility biomarkers

open access: yesAndrology, EarlyView.
Abstract Background Predicting male fertility in farm animals remains a challenge. Seminal plasma (SP) contains a high amount of heterogeneous seminal extracellular vesicles (sEVs), believed involved in reproductive processes and maybe key to understanding male fertility.
Isabel Barranco   +6 more
wiley   +1 more source

Cross‐sectional and longitudinal metabolomics‐based profiles associated with oral contraceptive and progestin‐only pill use: A Finnish population‐based study

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
In a metabolomics study of over 200 metabolites in 1721 fertile‐aged women, we found that current use of combined oral contraceptives (COC), especially third‐generation and other COCs, is associated with altered levels of several metabolic measures compared to nonuse of hormonal contraception or to use of a levonorgestrel intrauterine device (LNG‐IUD).
Elena Toffol   +7 more
wiley   +1 more source

Predicting Surfactant Need at Birth: Failed Validation of a Bedside Method Using Gastric Aspirates

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim To validate a prototype point‐of‐care (POC) test for the lecithin/sphingomyelin (L/S) ratio by identifying the optimal L/S cut‐off for predicting surfactant need in preterm infants < 30 weeks' gestation using gastric aspirates (GAS) sampled at birth and to assess clinical feasibility.
Christian Heiring   +9 more
wiley   +1 more source

Maternal Oncological Disease and Congenital Pneumonia Are New Independent Risk Factors for Surfactant Requirements in Late Preterm Infants

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim The purpose of this study was to evaluate the incidence of respiratory distress syndrome (RDS) in late preterm (LPT) infants. We also aimed to identify the risk factors associated with surfactant requirement and the clinical outcomes associated with surfactant therapy.
Simonetta Costa   +8 more
wiley   +1 more source

The physiological and pathological effects of sphingolipid metabolism and signaling in the central nervous system

open access: yesBrain Pathology, EarlyView.
Sphingolipids are vital components of cell membranes. Metabolic disruptions of sphingolipids, including ceramide and sphingosine‐1‐phosphate, are linked to neurological disorders. This article summarizes the classification, structure, and metabolic processes of sphingolipids, and the physiological and pathological effects of sphingolipid metabolism and
Tian Li   +7 more
wiley   +1 more source

Trifunctional sphingomyelin derivatives enable nanoscale resolution of sphingomyelin turnover in physiological and infection processes via expansion microscopy

open access: yesNature Communications
Sphingomyelin is a key molecule of sphingolipid metabolism, and its enzymatic breakdown is associated with various infectious diseases. Here, we introduce trifunctional sphingomyelin derivatives that enable the visualization of sphingomyelin distribution
Marcel Rühling   +14 more
doaj   +1 more source

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