Results 221 to 230 of about 81,593 (273)

Sphingomyelin and Cholesterol Promote HIV-1 gp41 Pretransmembrane Sequence Surface Aggregation and Membrane Restructuring [PDF]

, 2002
Asier Sáez‐Cirión, Shlomo Nir, Maier Lorizate, Aitziber Agirre, Antonio Cruz, Jesús Pérez‐Gil, José L. Nieva   +6 more
openalex   +1 more source

Robust Diagnostic and Therapeutic Biomarkers for Tuberculosis Identified Through Multi‐Omics and Mendelian Randomization Analysis

MedComm, Volume 7, Issue 1, January 2026.
We performed UPLC‐MS/MS lipidomics and DIA proteomics on plasma from healthy controls, active TB patients, and cured patients, and used Mendelian randomization to prioritize diagnostic and cure biomarkers. Multi‐omics random‐forest models based on these biomarkers showed excellent performance for diagnosis and cure monitoring.
Chenglin Zhu, Jiaxi Chen, Ying Li, Qi Zhang, Qiqi Lu, Ningxuan Zhang, Hao Fan, Muhammad Mahtab Aslam Khan Khakwani, Lei Zhang, Ji‐Cheng Li   +9 more
wiley   +1 more source

Transbilayer asymmetry and sphingomyelin composition modulate the preferential membrane partitioning of the nicotinic acetylcholine receptor in Lo domains

, 2015
Vanesa Liliana Perillo, Daniel A. Peñalva, Alejandro J. Vitale, Francisco J. Barrantes, Silvia S. Antollini   +4 more
openalex   +2 more sources

CCR2 Orchestrates Preferential Homing and Therapeutic Efficacy of Gingival Mesenchymal Stem Cell‐Derived Extracellular Vesicles in Rheumatoid Arthritis

MedComm, Volume 7, Issue 1, January 2026.
CCR2 orchestrates preferential homing of GMSC‐derived extracellularvesicles to inflamed joints in rheumatoid arthritis. ABSTRACT The clinical utility of mesenchymal stem cells (MSCs) is often limited by pulmonary entrapment and poor systemic distribution, particularly in diseases constrained by physiological barriers such as rheumatoid arthritis (RA ...
Jingrong Chen, Xiao Guan, Wenbin Wu, Luyao Wu, Yan Liu, Donglan Zeng, Junlong Dang, Jun Zhao, Julie Wang, Jia Yuan, Xiaoli Fan, Yunfeng Pan, Nancy Olsen, Song Guo Zheng   +13 more
wiley   +1 more source

Potential endogenous lipid ligands for the nuclear receptor transcription factor Steroidogenic Factor-1. [PDF]

Adv Biol Regul
Campbell AN, Blind RD.
europepmc   +1 more source

A multi‐omic biomarker signature in pre‐treatment rectal tumours stratifies patients with different pathological responses to neoadjuvant treatment

Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.
Laura E. Kane, Croí E. Buckley, Rebecca M. O'Brien, Meghana S. Menon, Aisling B. Heeran, Xiaofei Yin, Timothy S. Nugent, Noel E. Donlon, John V Reynolds, Adnan Hafeez, Diarmuid S. O'Ríordáin, Robert A. Hannon, Paul Neary, Reza Kalbassi, Brian J. Mehigan, Paul H. McCormick, Cara Dunne, John O. Larkin, Lorraine Brennan, Michael E. Kelly, Jacintha O'Sullivan, Niamh Lynam‐Lennon   +21 more
wiley   +1 more source

Modulators of Diacylglycerol Kinase Activity: A Review of Advances and Challenges

Medicinal Research Reviews, Volume 46, Issue 1, Page 149-175, January 2026.
ABSTRACT Catalyzing the conversion of diacylglycerol (DAG) in phosphatidic acid (PA), diacylglycerol kinases (DGKs) play a pivotal role in all the physiological processes modulated by these two bioactive lipids, such as lipid metabolism and immune regulation.
Luisa Racca, Gianluca Baldanzi, Alberto Massarotti   +2 more
wiley   +1 more source

Exploring Causal Associations Between Plasma Metabolites and Autism Spectrum Disorder. [PDF]

Alpha Psychiatry
Shi S, Baranova A, Cao H, Zhang F.
europepmc   +1 more source

Computational modelling of lipid bilayers with sphingomyelin and sterols

, 2007
Perttu Niemelä
openalex   +1 more source

The Gut Microbiota–Insulin Resistance Axis: Mechanisms, Clinical Implications, and Therapeutic Potential

FASEB BioAdvances, Volume 8, Issue 1, January 2026.
Dysbiosis‐induced alterations in microbial metabolite production promote intestinal barrier disruption and systemic inflammation, driving insulin resistance and metabolic dysfunction. Microbiota‐targeting therapies represent promising approaches to restore host metabolic health.
Mohamad Al Qassab, Nadim Chaarani, Amira Hamou, Rasha Harb, Ahmad Jradi, Mira Zeineddine, Hilda E. Ghadieh, Ziad Abi Khattar, Sami Azar, Amjad Kanaan, Frederic Harb   +10 more
wiley   +1 more source