Results 41 to 50 of about 81,593 (273)
Molecules, 2022 Reactive oxygen species (ROS) generated by ultraviolet (UV) exposure cause skin barrier dysfunction, which leads to dry skin. In this study, the skin moisturizing effect of sphingomyelin-containing milk phospholipids in UV-induced hairless mice was ...
Yejin Ahn +4 more
doaj +1 more source
Cells, 2022 The biomarkers of Parkinson’s disease (PD) remain to be investigated. This work aimed to identify blood biomarkers for PD using targeted metabolomics analysis.
Kuo-Hsuan Chang +5 more
doaj +1 more source
In vivo stability of ester- and ether-linked phospholipid-containing liposomes as measured by perturbed angular correlation spectroscopy [PDF]
, 1988 To evaluate liposome formulations for use as intracellular sustained-release drug depots, we have compared the uptake and degradation in rat liver and spleen of liposomes of various compositions, containing as their bulk phospholipid an ether-linked ...
Baldeschwieler, John D. +2 more
core +1 more source
Changes in Serum Sphingomyelin After Roux-en-Y Gastric Bypass Surgery Are Related to Diabetes Status
Frontiers in Endocrinology, 2018 Metabolic surgery is superior to lifestyle intervention in reducing weight and lowering glycemia and recently suggested as treatment for type 2 diabetes mellitus.
Elin Rebecka Carlsson +3 more
doaj +1 more source
Discrimination of prostate cancer cells and non-malignant cells using secondary ion mass spectrometry [PDF]
, 2008 This communication utilises Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) combined with multivariate analysis to obtain spectra from the surfaces of three closely related cell lines allowing their discrimination based upon mass spectral ...
Baker, Matthew James +5 more
core +1 more source
Sphingolipids and cholesterol modulate membrane susceptibility to cytosolic phospholipase A2
Journal of Lipid Research, 2000 Modulation of cytosolic phospholipase A2 (cPLA2) activity by sphingomyelin (SPH), ceramide (Cer), and cholesterol (Chol) was investigated in CHO-2B cells activated by the calcium ionophore A23187 and epinephrine.
Elsa Klapisz +4 more
doaj +1 more source
Journal of Lipid Research, 2020 The backbone of all sphingolipids (SLs) is a sphingoid long-chain base (LCB) to which a fatty acid is N-acylated. Considerable variability exists in the chain length and degree of saturation of both of these hydrophobic chains, and recent work has ...
Iris D. Zelnik +7 more
doaj +1 more source
Perturbed cholesterol and vesicular trafficking associated with dengue blocking in Wolbachia-infected Aedes aegypti cells [PDF]
, 2017 Wolbachia are intracellular maternally inherited bacteria that can spread through insect populations and block virus transmission by mosquitoes, providing an important approach to dengue control.
Ant, Thomas H. +9 more
core +3 more sources
Genetics in Medicine OpenAcid sphingomyelinase deficiency (ASMD) is a rare progressive genetic disorder caused by pathogenic variants in the SMPD1 gene causing low or absent activity of the enzyme acid sphingomyelinase, resulting in subsequent accumulation of its substrate ...
Monica Kumar +8 more
doaj +1 more source
Atomistic simulations of a multicomponent asymmetric lipid bilayer
, 2012 The cell membrane is inherently asymmetric and heterogeneous in its composition, a feature that is crucial for its function. Using atomistic molecular dynamics simulations, the physical properties of a 3-component asymmetric mixed lipid bilayer system ...
Polley, Anirban +2 more
core +1 more source