Results 21 to 30 of about 78,947 (270)
Experimental Biology and Medicine, 1964 SummaryThe sphingomyelin region of human plasma lipids, entirely free from lecithin, has been fractionated into two components by thin-layer chromatography. Both components had properties characteristic of sphingomyelins, but markedly different fatty acid patterns, acids above C20 being concentrated in the less-polar material.
P D, WOOD, S, HOLTON
openaire +2 more sources
Depletion of Host and Viral Sphingomyelin Impairs Influenza Virus Infection
Frontiers in Microbiology, 2020 Influenza A virus (IAV) is a major human respiratory pathogen causing annual epidemics as well as periodic pandemics. A complete understanding of the virus pathogenesis and host factors involved in the viral lifecycle is crucial for developing novel ...
Amani Audi +9 more
doaj +1 more source
Chlamydial infection from outside to inside [PDF]
, 2019 Chlamydia are obligate intracellular bacteria, characterized by a unique biphasic developmental cycle. Specific interactions with the host cell are crucial for the bacteria's survival and amplification because of the reduced chlamydial genome.
Gitsels, Arlieke +2 more
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Release of cholesterol-rich particles from the macrophage plasma membrane during movement of filopodia and lamellipodia. [PDF]
, 2019 Cultured mouse peritoneal macrophages release large numbers of ~30-nm cholesterol-rich particles. Here, we show that those particles represent fragments of the plasma membrane that are pulled away and left behind during the projection and retraction of ...
Fong, Loren G +11 more
core +3 more sources
MARCH1 protects the lipid raft and tetraspanin web from MHCII proteotoxicity in dendritic cells [PDF]
, 2018 Dendritic cells (DCs) produce major histocompatibility complex II (MHCII) in large amounts to function as professional antigen presenting cells. Paradoxically, DCs also ubiquitinate and degrade MHCII in a constitutive manner.
Anderson +54 more
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Lipids in Health and Disease, 2011 Background Studies have shown that plasma high density lipoprotein cholesterol levels are negatively correlated with the development of atherosclerosis, whereas epidemiological studies have also shown that plasma sphingomyelin level is an independent ...
Li Yue +4 more
doaj +1 more source
Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase. [PDF]
, 1994 Intracellular pathways leading from membrane receptor engagement to apoptotic cell death are still poorly characterized. We investigated the intracellular signaling generated after cross-linking of CD95 (Fas/Apo-1 antigen), a broadly expressed cell ...
Azuma, M +7 more
core +2 more sources
Journal of Lipid Research, 2005 We report the synthesis and characterization of a novel thiourea derivative of sphingomyelin (AD2765). In vitro assays using pure enzyme and/or cell extracts revealed that this compound inhibited the hydrolysis of BODIPY-conjugated or 14C-labeled ...
Peter I. Darroch +5 more
doaj +1 more source
Untargeted Lipidomic Analysis to Broadly Characterize the Effects of Pathogenic and Non-Pathogenic Staphylococci on Mammalian Lipids [PDF]
, 2018 Modification of the host lipidome via secreted enzymes is an integral, but often overlooked aspect of bacterial pathogenesis. In the current era of prevalent antibiotic resistance, knowledge regarding critical host pathogen lipid interactions has the ...
Baker, Paul RS +5 more
core +4 more sources
Бюллетень сибирской медицины, 2005 At inflammation process development caused by CCl4 morphological and functional research of 200 rats liver tissue was carried out. The liposomes loaded by the components of a sphingomyelin lipid cycle – sphingomyelin and ceramide were administed.
R. Z. Zainagetdinov +4 more
doaj +1 more source