Comment on "SMPDL3B as a novel biomarker and therapeutic target in myalgic encephalomyelitis" critical considerations on biomarker validation and Supraphysiological drug concentrations. [PDF]
J Transl MedChen J, Yan L.
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Lipids regulate epidermal growth factor receptor activation by its ligands. [PDF]
Biochem Soc TransHutchison JM, Lemmon MA.
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Molecular Maestro in the Lung: The Sphingolipid Rheostat. [PDF]
Am J Respir Cell Mol BiolRojas-Quintero J, Polverino F.
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Olipudase alfa treatment for pediatric acid sphingomyelinase deficiency in Egypt: A prospective, observational cohort study with an interventional subgroup. [PDF]
Mol Genet Metab RepArafa NA, Mahfouz A, Anwar S, Marzouk I.
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Simplifying complexity: genetically resculpting glycosphingolipid synthesis pathways in mice to reveal function [PDF]
, 2014 core +1 more source
Longitudinal analysis of lipid changes in the sciatic nerve caused by overexpression of PMP22 in murine models of CMT1A. [PDF]
J Lipid ResHellings TP +12 more
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Early secretory pathway-resident Zn transporter proteins contribute to cellular sphingolipid metabolism through activation of sphingomyelin phosphodiesterase 1Sphingomyelin phosphodiesterase 1 (SMPD1) converts sphingomyelin into ceramide and phosphocholine; hence, loss of SMPD1 function causes abnormal accumulation of sphingomyelin in lysosomes, which results in the lipid-storage disorder Niemann-Pick disease (types A and B). SMPD1 activity is dependent on zinc, which is coordinated at the active site of the
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An update on schistosomicide and tumoricide in the future: arachidonic acid. [PDF]
Lipids Health DisTallima H, El Ridi R.
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