Results 71 to 80 of about 11,288 (198)

Plasma sphingomyelins increase in pre-diabetic Korean men with abdominal obesity.

open access: yesPLoS ONE, 2019
Abdominal or visceral obesity is a well-known risk factor for metabolic diseases. However, whether abdominal obesity significantly affects plasma lipid profile during the development of type 2 diabetes has not been fully elucidated.
Seung-Soon Im   +6 more
doaj   +1 more source

Lipid bilayers containing sphingomyelins and ceramides of varying N-acyl lengths: A glimpse into sphingolipid complexity [PDF]

open access: yes, 2014
The thermotropic properties of aqueous dispersions of sphingomyelins (SM) and ceramides (Cer) with N-acyl chains varying from C6:0 to C24:1, either pure or in binary mixtures, have been examined by differential scanning calorimetry.
Alonso, Alicia   +5 more
core   +1 more source

ATPase activity of human ABCG1 is stimulated by cholesterol and sphingomyelin[S]

open access: yesJournal of Lipid Research, 2013
ATP-binding cassette protein G1 (ABCG1) is important for the formation of HDL. However, the biochemical properties of ABCG1 have not been reported, and the mechanism of how ABCG1 is involved in HDL formation remains unclear. We established a procedure to
Hiroshi Hirayama   +4 more
doaj   +1 more source

Epidermal sphingomyelins are precursors for selected stratum corneum ceramides

open access: yesJournal of Lipid Research, 2000
Epidermal ceramides (Cer) comprise a heterogeneous family of seven species, including two unique ω-hydroxylated Cer, that are key components of the stratum corneum (SC) intercellular lamellar membranes responsible for the epidermal permeability barrier ...
Yoshikazu Uchida   +9 more
doaj   +1 more source

Additional file 1: of Untargeted Mass Spectrometry Lipidomics identifies correlation between serum sphingomyelins and plasma cholesterol

open access: yes, 2019
Figure S1. Representative total ion current (TIC) chromatogram profiles in positive (A) & negative (B) ion modes. Data were obtained following untargeted liquid chromatography mass spectrometry (LC-MS) analysis with a CSH C18 columnof a quality control ...
Pierre Zalloua (490360)   +14 more
core   +1 more source

Membrane Properties of D-erythro-N-acyl Sphingomyelins and Their Corresponding Dihydro Species [PDF]

open access: yes, 2001
We have prepared acyl chain-defined D-erythro-sphingomyelins and D-erythro-dihydrosphingomyelins and compared their properties in monolayer and bilayer membranes. Surface pressure/molecular area isotherms of D-erythro-N-16:0-sphingomyelin (16:0-SM) and D-
Slotte, J. Peter   +4 more
core   +1 more source

Coupled assay of sphingomyelin and ceramide molecular species by gas liquid chromatography

open access: yesJournal of Lipid Research, 2002
This study reports a single-step analysis of the molecular species of endogenous ceramides and of the ceramide moiety of sphingomyelins in biological samples, using gas liquid chromatography (GLC).
Claude Vieu   +8 more
doaj   +1 more source

Secreted sphingomyelins modulate low mammary cancer incidence observed in certain mammals

open access: yesScientific Reports, 2020
Determining mechanisms that naturally protect species from developing cancer is critical in order to prevent and treat cancer. Here, we describe a novel cancer-suppressing mechanism, via the secretion of bioactive factors by mammary cells, that is ...
Melissa M. Ledet   +6 more
doaj   +1 more source

Sphingomyelins in mosquito saliva modify the host lipidome to enhance transmission of flaviviruses by promoting viral protein levels

open access: yes
Mosquito saliva plays a determining role in flavivirus transmission. Here, we discover and elucidate how salivary lipids enhance transmission. Building upon our discovery of salivary extracellular vesicles (EV), we determined that lipids within mosquito ...
Revel, Justine   +16 more
core   +1 more source

Identification of a distinct pool of sphingomyelin involved in the sphingomyelin cycle.

open access: yesJournal of Biological Chemistry, 1994
Sphingomyelin (SM) is a membrane phosphosphingolipid that has recently been identified as a key component of the SM cycle. In this signal transduction pathway, extracellular inducers such as tumor necrosis factor alpha cause hydrolysis of membrane SM, resulting in the generation of the lipid second messenger ceramide. Only 10-20% of cellular SM appears
C M, Linardic, Y A, Hannun
openaire   +2 more sources

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