Results 71 to 80 of about 9,105 (228)

ATPase activity of human ABCG1 is stimulated by cholesterol and sphingomyelin[S]

Journal of Lipid Research, 2013
ATP-binding cassette protein G1 (ABCG1) is important for the formation of HDL. However, the biochemical properties of ABCG1 have not been reported, and the mechanism of how ABCG1 is involved in HDL formation remains unclear. We established a procedure to
Hiroshi Hirayama, Yasuhisa Kimura, Noriyuki Kioka, Michinori Matsuo, Kazumitsu Ueda   +4 more
doaj   +1 more source

Hybrid Quatsome‐Encapsulated Silver Nanoparticles as Stable Plasmonic Substrates for Surface‐Enhanced Raman Scattering

Journal of Raman Spectroscopy, EarlyView.
In this work, silver nanoparticles encapsulated within quatsome membranes have shown to preserve their plasmonic properties for at least 165 days without aggregation. These hybrid nanostructures enable strong SERS enhancement of pyrene and Prodan by confining the molecules within a few nanometers from the silver surface.
Renato Cezar Peramezza Ribeiro, Caio Hiroaki Miyake, Pedro Henrique Figueiredo Backes Costa, Jhenifer Hallen Braga Mauricio, Ana Luiza Correa Januário, Diogo Soga, Evandro Luiz Duarte, Márcia de Almeida Rizzutto, Rômulo Augusto Ando, Antonio Rodrigues da Cunha, Erix Alexander Milán‐Garcés   +10 more
wiley   +1 more source

Liposome Particle Size Prediction by In‐Line Process Analytical Technology (PAT)‐Integrated Machine Learning

Small Methods, EarlyView.
An in‐line PAT‐integrated ML strategy for microfluidic liposome synthesis accurately predicted particle size from formulation parameters and fluoresence sensing data. The model captured both seen and unseen conditions, demonstrating robust generalization and process control with low error.
Junghu Lee, Nozomi Morishita Watanabe, Noriko Yoshimoto, Seonghyeon Eom, Moon Kyu Kwak, Ho‐Sup Jung, Hiroshi Umakoshi   +6 more
wiley   +1 more source

Epidermal sphingomyelins are precursors for selected stratum corneum ceramides

Journal of Lipid Research, 2000
Epidermal ceramides (Cer) comprise a heterogeneous family of seven species, including two unique ω-hydroxylated Cer, that are key components of the stratum corneum (SC) intercellular lamellar membranes responsible for the epidermal permeability barrier ...
Yoshikazu Uchida, Mariko Hara, Hiroyuki Nishio, Ellen Sidransky, Shintaro Inoue, Fujio Otsuka, Akemi Suzuki, Peter M. Elias, Walter M. Holleran, Sumiko Hamanaka   +9 more
doaj   +1 more source

TcALS knockdown accelerates metamorphosis via insulin signaling in Tribolium castaneum

Insect Science, EarlyView.
RNAi silencing of TcALS accelerates larva‐to‐pupa metamorphosis in Tribolium castaneum. Abstract Insect metamorphosis is an evolutionary adaptation precisely regulated by nutritional and hormonal cues. The red flour beetle Tribolium castaneum, a major stored‐product pest, serves as an excellent model for studying this process.
Min Li, Jie Chen, Zi‐Ye Wang, Fei‐Feng Wang, Lu‐Lu Dong, Jun Pan, Min‐Er Li, Lin Yu, Wen Sang   +8 more
wiley   +1 more source

Secreted sphingomyelins modulate low mammary cancer incidence observed in certain mammals

Scientific Reports, 2020
Determining mechanisms that naturally protect species from developing cancer is critical in order to prevent and treat cancer. Here, we describe a novel cancer-suppressing mechanism, via the secretion of bioactive factors by mammary cells, that is ...
Melissa M. Ledet, Rebecca M. Harman, Jennifer C. Fan, Emily Schmitt-Matzen, Maria Elena Diaz-Rubio, Sheng Zhang, Gerlinde R. Van de Walle   +6 more
doaj   +1 more source

Identification of a distinct pool of sphingomyelin involved in the sphingomyelin cycle.

Journal of Biological Chemistry, 1994
Sphingomyelin (SM) is a membrane phosphosphingolipid that has recently been identified as a key component of the SM cycle. In this signal transduction pathway, extracellular inducers such as tumor necrosis factor alpha cause hydrolysis of membrane SM, resulting in the generation of the lipid second messenger ceramide. Only 10-20% of cellular SM appears
C M, Linardic, Y A, Hannun
openaire   +2 more sources

Emollient Formulations and Skin Barrier Practices in the Context of Eczema and Food Allergy Prevention

Allergy, EarlyView.
ABSTRACT The skin is far from a passive shield; it functions as a dynamic “living barrier” whose structural and immunological integrity is paramount in preventing atopic dermatitis (AD) and the subsequent progression of the atopic march toward food allergy (FA).
Klaudia Ryczaj, Donald Y. M. Leung, Carina Venter, Barbara Sozańska, Helen A. Brough   +4 more
wiley   +1 more source

Coupled assay of sphingomyelin and ceramide molecular species by gas liquid chromatography

Journal of Lipid Research, 2002
This study reports a single-step analysis of the molecular species of endogenous ceramides and of the ceramide moiety of sphingomyelins in biological samples, using gas liquid chromatography (GLC).
Claude Vieu, François Tercé, Françoise Chevy, Corinne Rolland, Ronald Barbaras, Hugues Chap, Claude Wolf, Bertrand Perret, Xavier Collet   +8 more
doaj   +1 more source

Proteomic profile of CSF obtained at the time of diagnosis determines amyotrophic lateral sclerosis progression and survival: CXCL7 levels in disease prognosis and survival

Brain Pathology, EarlyView.
Untargeted multiomic profiling of cerebrospinal fluid reveals that proteomic, but not lipidomic, signatures robustly distinguish ALS patients from controls and stratify individuals by survival, highlighting marked molecular differences between short survival and long survival disease.
Sergio Roca‐Pereira, Yaiza López‐Sampere, Pol Mengod‐Soler, Mario Peña‐Fonteboa, Carla Marco, Alejandro Caravaca‐Puchades, Raúl Domínguez, Juan Francisco Vázquez‐Costa, Enrique Santamaría, Joaquín Fernández‐Irigoyen, María J. Colomina, Isabel León Moreno, Antonio Martínez Yélamos, Sergio Martínez Yélamos, Gabriel Santpere, Elia Obis, Manuel Portero‐Otín, Gerard Piñol‐Ripoll, Mónica Povedano, Pol Andrés‐Benito   +19 more
wiley   +1 more source