Results 161 to 170 of about 61,732 (250)

Potential Role of Sphingosine-1-Phosphate and Its Receptors in the Reparative Processes of the Adult Brain. [PDF]

Int J Mol Sci
Gutner UA, Shupik MA, Alessenko A.
europepmc   +1 more source

Advances in the treatment of systemic lupus erythematosus: Biologicals, small‐molecular agents, and cell‐depleting therapies coming to the clinic

Journal of Internal Medicine, Volume 300, Issue 4, Page 461-479, October 2026.
Abstract Systemic lupus erythematosus (SLE; lupus) remains a particular challenge for the practicing clinician on account of its chronic undulating and unpredictable course, its diverse manifestations, and—until recently—limited treatment options all associated with considerable downsides.
Ronald van Vollenhoven
wiley   +1 more source

Associations of sphingosine-1-phosphate with thyroid function and structure: a cross-sectional population-based study. [PDF]

Eur Thyroid J
Bähr L, Gross S, Dörr M, Rauch BH, Friedrich N, Schwedhelm E, Daum G, Templin C, Markus MR, Völzke H, Bahls M, Ittermann T.   +11 more
europepmc   +1 more source

Acute exercise‐induced lipolysis and increase in levels of fatty acid esters of hydroxy fatty acids in adipose tissue are impaired in obese and aged mice

Experimental Physiology, Volume 111, Issue 10, Page 4457-4497, 1 October 2026.
Abstract Improving adipose tissue (AT) metabolism through exercise might increase production of lipokines from the fatty acid esters of hydroxy fatty acids (FAHFA) family. Although exercise training can increase insulin sensitivity and levels of specific FAHFA in AT and the circulation in humans, the effects of acute exercise on FAHFA levels remain ...
Marko Mitrovic, Olga Horakova, Martin Riecan, Veronika Kleinova, Tomas Cajka, Lenka Rossmeislova, Ondrej Kuda, Martin Rossmeisl   +7 more
wiley   +1 more source

Generation of Allogeneic CAR‐T Circumvents Functional Deficits in Patient‐Derived Autologous Product for Glioblastoma

International Journal of Cancer, Volume 159, Issue 6, Page 1521-1534, 15 September 2026.
Clinical trials of chimeric antigen receptor T‐cell (CAR‐T) therapies in glioblastoma have shown limited clinical benefits. Whether this may be explained by the basal quality of CAR‐T products, which are currently generated using patient, autologous T‐cells, has been little explored.
Sabra K. Salim, Muhammad Vaseem Shaikh, Jeffrey Wei, William T. Maich, Alisha Anand, Oliver Y. Tang, Minomi K. Subapanditha, Zahra Alizada, Yujin Suk, Manoj Singh, Kui Zhai, Aapti Khanna, Benjamin Brakel, Vassil Dimitrov, Zoya Tabunshchyk, Katie Chan, Kevin R. Brown, Parvez Vora, Donald M. O'Rourke, Zev A. Binder, Chitra Venugopal, Jason Moffat, Sheila K. Singh   +22 more
wiley   +1 more source

Multi-omics profiling reveals sphingolipid metabolism reprogramming of tumor-conditioned MDSCs in cervical cancer. [PDF]

BMC Cancer
Mai Q, Chi C, Wang X, Chen Y, Zou Q, Chen Q, Zeng F, Wei M, Chen Y, Wang A, Liao Y, Xiao Y, Li X, Yan Q, Zhan L, Wei H, Jing X, Du Q, Liu J.   +18 more
europepmc   +1 more source

Effects of sphingosine-1-phosphate receptor modulators on remyelination in multiple sclerosis: evidence from <i>in vitro</i> experiments, animal models and human studies. [PDF]

Front Immunol
Ricigliano VAG.
europepmc   +1 more source

Fasudil induces anti-inflammatory transcriptomic changes and increased proliferation in human trisomy 21 neural progenitor cells. [PDF]

Biol Open
Baxter LL, Lee SE, Fuentes KA, Mosley IA, Raymond JD, Guedj F, Zhou D, Slonim DK, Glotfelty EJ, Tweedie D, Grieg NH, Bianchi DW.   +11 more
europepmc   +1 more source

The Enzymatic Synthesis of Sphingosine

Journal of Biological Chemistry, 1958
R O, BRADY, G J, KOVAL
openaire   +2 more sources

Fungal Infections Associated with Sphingosine 1-Phosphate Receptor Modulators: Immunological Mechanisms, Clinical Patterns, and Management Considerations. [PDF]

Microorganisms
Yazdan KM, Madam ST, Pasula S.
europepmc   +1 more source