Results 41 to 50 of about 132,886 (258)

Biochemical and pharmacological study of venom of the wolf spider Lycosa singoriensis

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2009
The wolf spider Lycosa singoriensis is a large and venomous spider distributed throughout northwestern China. Like other spider venoms, the wolf spider venom is a chemical cocktail.
ZH Liu, W Qian, J Li, Y Zhang, S Liang
doaj   +1 more source

Spider-Venom Peptides as Therapeutics [PDF]

open access: yesToxins, 2010
Spiders are the most successful venomous animals and the most abundant terrestrial predators. Their remarkable success is due in large part to their ingenious exploitation of silk and the evolution of pharmacologically complex venoms that ensure rapid subjugation of prey.
Natalie J. Saez   +6 more
openaire   +4 more sources

De Novo Transcriptome Analysis of the Venom of Latrodectus geometricus with the Discovery of an Insect-Selective Na Channel Modulator

open access: yesMolecules, 2021
The brown widow spider, Latrodectus geometricus, is a predator of a variety of agricultural insects and is also hazardous for humans. Its venom is a true pharmacopeia representing neurotoxic peptides targeting the ion channels and/or receptors of both ...
Pornsawan Khamtorn   +5 more
doaj   +1 more source

The venom gland transcriptome of Latrodectus tredecimguttatus revealed by deep sequencing and cDNA library analysis. [PDF]

open access: yesPLoS ONE, 2013
Latrodectus tredecimguttatus, commonly known as black widow spider, is well known for its dangerous bite. Although its venom has been characterized extensively, some fundamental questions about its molecular composition remain unanswered.
Quanze He   +5 more
doaj   +1 more source

Proteotranscriptomic Insights into the Venom Composition of the Wolf Spider Lycosa tarantula

open access: yesToxins, 2020
Spider venoms represent an original source of novel compounds with therapeutic and agrochemical potential. Whereas most of the research efforts have focused on large mygalomorph spiders, araneomorph spiders are equally promising but require more ...
Dominique Koua   +7 more
doaj   +1 more source

Intersexual Differences in the Gene Expression of Phoneutria depilata (Araneae, Ctenidae) Toxins Revealed by Venom Gland Transcriptome Analyses

open access: yesToxins, 2023
The wandering spider, Phoneutria depilata, is one of Colombia’s most active nocturnal arthropod predators of vertebrates and invertebrates. Its venom has been a relevant subject of study in the last two decades.
Diego Sierra Ramírez   +7 more
doaj   +1 more source

Spider Venoms: Biochemical Aspects [PDF]

open access: yesAmerican Zoologist, 1969
SYNOPSIS. The venoms of spiders are quite complex and contain an array of biologically active components. The majority of studies on the biochemical aspects of these venoms have utilized four species: Phoneutria fera, Lycosa erythrognatha, Atrax robustus , and Latrodectus mactans .
openaire   +2 more sources

Brown Recluse spider bite mediated hemolysis: clinical features, a possible role for complement inhibitor therapy, and reduced RBC surface glycophorin A as a potential biomarker of venom exposure. [PDF]

open access: yesPLoS ONE, 2013
The venom of Loxosceles reclusa (Brown Recluse spider) can cause a severe, life-threatening hemolysis in humans for which no therapy is currently available in the USA beyond supportive measures.
Eric A Gehrie, Hui Nian, Pampee P Young
doaj   +1 more source

Spider venom-derived peptide induces hyperalgesia in Nav1.7 knockout mice by activating Nav1.9 channels

open access: yesNature Communications, 2020
The sodium channels Nav1.7, Nav1.8 and Nav1.9 are critical for pain perception in peripheral nociceptors. Loss of function of Nav1.7 leads to congenital insensitivity to pain in humans.
Xi Zhou   +14 more
semanticscholar   +1 more source

A Novel Insecticidal Spider Peptide that Affects the Mammalian Voltage-Gated Ion Channel hKv1.5

open access: yesFrontiers in Pharmacology, 2021
Spider venoms include various peptide toxins that modify the ion currents, mainly of excitable insect cells. Consequently, scientific research on spider venoms has revealed a broad range of peptide toxins with different pharmacological properties, even ...
Diana Alvarado   +13 more
doaj   +1 more source

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