Results 71 to 80 of about 98,663 (213)
Cancer pain: current practice and emerging targets
British Journal of Pharmacology, EarlyView.Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye +5 more
wiley +1 more source
Histopathological analysis and in situ localisation of Australian tiger snake venom in two clinically envenomed domestic animals [PDF]
, 2011 Objective: To assess histopathological changes in clinically envenomed tiger snake patients and identify tissue specific localisation of venom toxins using immunohistochemistry.
Jacoby-Alner, T.E. +5 more
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Toxins, 2019 Brown spider envenomation results in dermonecrosis with gravitational spreading characterized by a marked inflammatory reaction and with lower prevalence of systemic manifestations such as renal failure and hematological disturbances. Several toxins make
Daniele Chaves-Moreira +11 more
doaj +1 more source
British Journal of Pharmacology, EarlyView.Background and Purpose Spinal muscular atrophy (SMA) is a motor neuron disease caused by SMN1 gene loss, leading to reduced survival motor neuron (SMN) protein and progressive motor neuron degeneration. Although SMN‐restoring therapies improve outcomes, residual disease burden and non‐curative efficacy underscore the need for complementary treatments ...
Fernanda C. Cardoso +3 more
wiley +1 more source
A normal form for spider diagrams of order [PDF]
, 2014 We develop a reasoning system for an Euler diagram based visual logic, called spider diagrams of order. We de- fine a normal form for spider diagrams of order and provide an algorithm, based on the reasoning system, for producing diagrams in our normal ...
Simon Thompson +7 more
core +1 more source
Children &Society, EarlyView.ABSTRACT Modern deaths have become reiterations. That is, despite exhibiting a seemingly high‐level of diversity in death's representations in everyday lives, death suffers from a particular onto‐epistemological poverty that prevents it from being imagined otherwise.
Zhaoxi Zheng +2 more
wiley +1 more source
Fragments of Spider Diagrams of Order and their Relative Expressiveness [PDF]
, 2010 Investigating the expressiveness of a diagrammatic logic provides insight into how its syntactic elements interact at the semantic level. Moreover, it allows for comparisons with other notations. Various expressiveness results for diagrammatic logics are
Simon Thompson +7 more
core +1 more source
The Cytotoxic Mode of Action of the Venom of Cupiennius salei (Ctenidae) [PDF]
, 2013 The venom of the ctenid spider Cupiennius salei (Fig.16.1) is rich in components which belong to different functional groups. Besides low molecular mass compounds, the venom contains several disulphide-rich peptides, also called mini-proteins, which act ...
Kuhn-Nentwig, Lucia Gerda +1 more
core +2 more sources
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary Background and Objectives Teledermatology has become an essential part of dermatological care, although challenges in its implementation remain. We conducted a real‐life survey on video consultations over a one‐year period to assess satisfaction and identify barriers.
Felix von Krogh +4 more
wiley +1 more source
Tissue Localization and Extracellular Matrix Degradation by PI, PII and PIII Snake Venom Metalloproteinases: Clues on the Mechanisms of Venom-Induced Hemorrhage [PDF]
, 2015 20 páginas, 4 figuras, 3 tablas y 7 tablas en material suplementario.Snake venom hemorrhagic metalloproteinases (SVMPs) of the PI, PII and PIII classes were compared in terms of tissue localization and their ability to hydrolyze basement membrane ...
Calvete, JJ +47 more
core +1 more source