VenoMS—A Website for the Low Molecular Mass Compounds in Spider Venoms [PDF]
Metabolites, 2020 Spider venoms are highly complex mixtures. Numerous spider venom metabolites are uniquely found in spider venoms and are of interest concerning their potential use in pharmacology, agriculture, and cosmetics.
Yvonne M. Forster +4 more
doaj +2 more sources
Recent Advances in Research on Widow Spider Venoms and Toxins [PDF]
Toxins, 2015 Widow spiders have received much attention due to the frequently reported human and animal injures caused by them. Elucidation of the molecular composition and action mechanism of the venoms and toxins has vast implications in the treatment of ...
Shuai Yan, Xianchun Wang
doaj +2 more sources
Spider-Venom Peptides as Therapeutics [PDF]
Toxins, 2010 Spiders are the most successful venomous animals and the most abundant terrestrial predators. Their remarkable success is due in large part to their ingenious exploitation of silk and the evolution of pharmacologically complex venoms that ensure rapid ...
Glenn F. King +6 more
doaj +4 more sources
A Web of Coagulotoxicity: Failure of Antivenom to Neutralize the Destructive (Non-Clotting) Fibrinogenolytic Activity of Loxosceles and Sicarius Spider Venoms [PDF]
Toxins, 2020 Envenomations are complex medical emergencies that can have a range of symptoms and sequelae. The only specific, scientifically-validated treatment for envenomation is antivenom administration, which is designed to alleviate venom effects.
Dwin Grashof +7 more
doaj +2 more sources
Prospects and challenges of recombinant spider venom enzymes: insights from Loxosceles and Phoneutria venom protease expressions [PDF]
Frontiers in Bioengineering and BiotechnologySpiders use chemically complex venoms to overpower prey. Such venoms are primarily composed of neurotoxic disulfide-rich peptides, linear peptides, and enzymes.
Josephine Dresler +11 more
doaj +2 more sources
Spider-Venom Peptides: Structure, Bioactivity, Strategy, and Research Applications
Molecules, 2023 Spiders (Araneae), having thrived for over 300 million years, exhibit remarkable diversity, with 47,000 described species and an estimated 150,000 species in existence. Evolving with intricate venom, spiders are nature’s skilled predators.
Ruiyin Guo +5 more
doaj +1 more source
Venom of the Brazilian spider Sicarius ornatus (Araneae, Sicariidae) contains active sphingomyelinase D: potential for toxicity after envenomation. [PDF]
PLoS Neglected Tropical Diseases, 2013 BACKGROUND:The spider family Sicariidae includes two genera, Sicarius and Loxosceles. Bites by Sicarius are uncommon in humans and, in Brazil, a single report is known of a 17-year old man bitten by a Sicarius species that developed a necrotic lesion ...
Priscila Hess Lopes +5 more
doaj +1 more source
A Novel Insecticidal Spider Peptide that Affects the Mammalian Voltage-Gated Ion Channel hKv1.5
Frontiers in Pharmacology, 2021 Spider venoms include various peptide toxins that modify the ion currents, mainly of excitable insect cells. Consequently, scientific research on spider venoms has revealed a broad range of peptide toxins with different pharmacological properties, even ...
Diana Alvarado +13 more
doaj +1 more source
Comparative venomic profiles of three spiders of the genus Phoneutria
Journal of Venomous Animals and Toxins including Tropical Diseases, 2022 Background: Spider venoms induce different physio-pharmacological effects by binding with high affinity on molecular targets, therefore being of biotechnological interest.
Frederico Francisco Fernandes +9 more
doaj +1 more source
A novel neurotoxin from venom of the spider, Brachypelma albopilosum. [PDF]
PLoS ONE, 2014 Spiders have evolved highly selective toxins for insects. There are many insecticidal neurotoxins in spider venoms. Although a large amount of work has been done to focus on neurotoxicity of spider components, little information, which is related with ...
Yunhua Zhong +7 more
doaj +1 more source