Venomic and pharmacological activity of Acanthoscurria paulensis (Theraphosidae) spider venom
In the present study we conducted proteomic and pharmacological characterizations of the venom extracted from the Brazilian tarantula Acanthoscurria paulensis, and evaluated the cardiotoxicity of its two main fractions. The molecular masses of the venom components were identified by mass spectrometry (MALDI-TOF-MS) after chromatographic separation ...
Caroline Barbosa Farias Mourão+11 more
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A Proteomics and Transcriptomics Investigation of the Venom from the Barychelid Spider Trittame loki (Brush-Foot Trapdoor) [PDF]
Although known for their potent venom and ability to prey upon both invertebrate and vertebrate species, the Barychelidae spider family has been entirely neglected by toxinologists. In striking contrast, the sister family Theraphosidae (commonly known as
Eivind A. B. Undheim+12 more
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A novel neurotoxin from venom of the spider, Brachypelma albopilosum. [PDF]
Spiders have evolved highly selective toxins for insects. There are many insecticidal neurotoxins in spider venoms. Although a large amount of work has been done to focus on neurotoxicity of spider components, little information, which is related with ...
Yunhua Zhong+7 more
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A Comparative Analysis of the Venom Gland Transcriptomes of the Fishing Spiders Dolomedes mizhoanus and Dolomedes sulfurous. [PDF]
Dolomedes sulfurous and Dolomedes mizhoanus are predaceous arthropods catching and feeding on small fish. They live in the same area and have similar habits.
Xunxun Xu+5 more
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The deep-rooted origin of disulfide-rich spider venom toxins
Spider venoms are a complex concoction of enzymes, polyamines, inorganic salts, and disulfide-rich peptides (DRPs). Although DRPs are widely distributed and abundant, their bevolutionary origin has remained elusive.
Naeem Yusuf Shaikh, Kartik Sunagar
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Brown Spider Venom Phospholipase-D Activity upon Different Lipid Substrates
Brown spider envenomation results in dermonecrosis, characterized by an intense inflammatory reaction. The principal toxins of brown spider venoms are phospholipase-D isoforms, which interact with different cellular membrane components, degrade ...
Daniele Chaves-Moreira+9 more
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Toxin diversity revealed by a transcriptomic study of Ornithoctonus huwena. [PDF]
Spider venom comprises a mixture of compounds with diverse biological activities, which are used to capture prey and defend against predators. The peptide components bind a broad range of cellular targets with high affinity and selectivity, and appear to
Yiya Zhang+10 more
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Preparation and validation of a systemic loxoscelism prediction protocol
Introduction: Systemic loxoscelism is the most severe complication of loxoscelism. The management of the cadre by health personnel presents a high variability due to factors that are currently unknown.
Rafael Pichardo-Rodriguez+3 more
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Biochemical and pharmacological study of venom of the wolf spider Lycosa singoriensis
The wolf spider Lycosa singoriensis is a large and venomous spider distributed throughout northwestern China. Like other spider venoms, the wolf spider venom is a chemical cocktail.
ZH Liu, W Qian, J Li, Y Zhang, S Liang
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