Enlightening the toxinological dark matter of spider venom enzymes [PDF]
npj BiodiversitySpiders produce highly adapted venoms featuring a complex mixture of biomolecules used mainly for hunting and defense. The most prominent components are peptidic neurotoxins, a major focus of research and drug development, whereas venom enzymes have been
Josephine Dresler +3 more
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Beyond venomous fangs: Uloboridae spiders have lost their venom but not their toxicity. [PDF]
BMC BiolPeng X +11 more
europepmc +4 more sources
Spider-Venom Peptides: Structure, Bioactivity, Strategy, and Research Applications
Molecules, 2023 Spiders (Araneae), having thrived for over 300 million years, exhibit remarkable diversity, with 47,000 described species and an estimated 150,000 species in existence. Evolving with intricate venom, spiders are nature’s skilled predators.
Ruiyin Guo +5 more
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Biotechnological Trends in Spider and Scorpion Antivenom Development [PDF]
, 2016 Spiders and scorpions are notorious for their fearful dispositions and their ability to inject venom into prey and predators, causing symptoms such as necrosis, paralysis, and excruciating pain.
Engmark, Mikael +5 more
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Venom of the Brazilian spider Sicarius ornatus (Araneae, Sicariidae) contains active sphingomyelinase D: potential for toxicity after envenomation. [PDF]
PLoS Neglected Tropical Diseases, 2013 BACKGROUND:The spider family Sicariidae includes two genera, Sicarius and Loxosceles. Bites by Sicarius are uncommon in humans and, in Brazil, a single report is known of a 17-year old man bitten by a Sicarius species that developed a necrotic lesion ...
Priscila Hess Lopes +5 more
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A Novel Insecticidal Spider Peptide that Affects the Mammalian Voltage-Gated Ion Channel hKv1.5
Frontiers in Pharmacology, 2021 Spider venoms include various peptide toxins that modify the ion currents, mainly of excitable insect cells. Consequently, scientific research on spider venoms has revealed a broad range of peptide toxins with different pharmacological properties, even ...
Diana Alvarado +13 more
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Spider-Venom Peptides as Bioinsecticides [PDF]
Toxins, 2012 Over 10,000 arthropod species are currently considered to be pest organisms. They are estimated to contribute to the destruction of ~14% of the world’s annual crop production and transmit many pathogens. Presently, arthropod pests of agricultural and health significance are controlled predominantly through the use of chemical insecticides ...
Monique J. Windley +5 more
openaire +4 more sources
Venomous spiders of Albania –does an increase of temperature influence the toxicity of spider venom?
Toxicon: X, 2022 Black widow spiders (Latrodectus sp.) are distributed worldwide, and in Albania the L. tredecimguttatus Rossi, 1790 has been the dominant spider. Other medically important spiders in Albania include the brown recluse with symptoms known as loxoscelism, the false black widow and the egg sac spiders; the last two inducing similar symptoms to a wasp sting.
Vrenozi, Blerina
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Comparative venomic profiles of three spiders of the genus Phoneutria
Journal of Venomous Animals and Toxins including Tropical Diseases, 2022 Background: Spider venoms induce different physio-pharmacological effects by binding with high affinity on molecular targets, therefore being of biotechnological interest.
Frederico Francisco Fernandes +9 more
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A novel neurotoxin from venom of the spider, Brachypelma albopilosum. [PDF]
PLoS ONE, 2014 Spiders have evolved highly selective toxins for insects. There are many insecticidal neurotoxins in spider venoms. Although a large amount of work has been done to focus on neurotoxicity of spider components, little information, which is related with ...
Yunhua Zhong +7 more
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