The deep-rooted origin of disulfide-rich spider venom toxins
eLife, 2023 Spider venoms are a complex concoction of enzymes, polyamines, inorganic salts, and disulfide-rich peptides (DRPs). Although DRPs are widely distributed and abundant, their bevolutionary origin has remained elusive.
Naeem Yusuf Shaikh, Kartik Sunagar
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Can we resolve the taxonomic bias in spider venom research?
Toxicon: X, 2019 The rate of discovery of new spider species greatly exceeds the rate of spider venom characterisation, leading to an increasing number of species with unstudied venoms.
Volker Herzig +2 more
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Dramatic expansion of the black widow toxin arsenal uncovered by multi-tissue transcriptomics and venom proteomics. [PDF]
, 2014 BackgroundAnimal venoms attract enormous interest given their potential for pharmacological discovery and understanding the evolution of natural chemistries.
Ayoub, Nadia A +4 more
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Brown Spider Venom Phospholipase-D Activity upon Different Lipid Substrates
Toxins, 2023 Brown spider envenomation results in dermonecrosis, characterized by an intense inflammatory reaction. The principal toxins of brown spider venoms are phospholipase-D isoforms, which interact with different cellular membrane components, degrade ...
Daniele Chaves-Moreira +9 more
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Toxin diversity revealed by a transcriptomic study of Ornithoctonus huwena. [PDF]
PLoS ONE, 2014 Spider venom comprises a mixture of compounds with diverse biological activities, which are used to capture prey and defend against predators. The peptide components bind a broad range of cellular targets with high affinity and selectivity, and appear to
Yiya Zhang +10 more
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Preparation and validation of a systemic loxoscelism prediction protocol
Revista de la Facultad de Medicina Humana, 2020 Introduction: Systemic loxoscelism is the most severe complication of loxoscelism. The management of the cadre by health personnel presents a high variability due to factors that are currently unknown.
Rafael Pichardo-Rodriguez +3 more
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Biochemical and pharmacological study of venom of the wolf spider Lycosa singoriensis
Journal of Venomous Animals and Toxins including Tropical Diseases, 2009 The wolf spider Lycosa singoriensis is a large and venomous spider distributed throughout northwestern China. Like other spider venoms, the wolf spider venom is a chemical cocktail.
ZH Liu, W Qian, J Li, Y Zhang, S Liang
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The envenomation of general physiology throughout the last century. [PDF]
, 2017 Toxins are the poisonous products of organisms. Toxins serve vital defensive and offensive functions for those that harbor them: stinging scorpions, pesticidal plants, sanguinary snakes, fearless frogs, sliming snails, noxious newts, and smarting spiders.
Sack, Jon T
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The Northern Widow Spider, Latrodectus Variolus (Araneae: Theridiiae), in Michigan [PDF]
, 2017 Until recently the species of widow spider occurring in Michigan was considered a variant of the black widow, Latrodectus mactans (Fabricius). Levi (1959) summarized and revised the worldwide genus Latrodectus, placing the southern areas of Illinois ...
Wilson, Louis F
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ArachnoServer 2.0, an updated online resource for spider toxin sequences and structures [PDF]
, 2011 ArachnoServer (www.arachnoserver.org) is a manually curated database providing information on the sequence, structure and biological activity of protein toxins from spider venoms.
Binford, G +8 more
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