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Brown Spider (Loxosceles genus) Venom Toxins: Tools for Biological Purposes
Toxins, 2011 Venomous animals use their venoms as tools for defense or predation. These venoms are complex mixtures, mainly enriched of proteic toxins or peptides with several, and different, biological activities.
Andrea Senff-Ribeiro +11 more
doaj +1 more source
The Northern Widow Spider, Latrodectus Variolus (Araneae: Theridiiae), in Michigan [PDF]
, 2017 Until recently the species of widow spider occurring in Michigan was considered a variant of the black widow, Latrodectus mactans (Fabricius). Levi (1959) summarized and revised the worldwide genus Latrodectus, placing the southern areas of Illinois ...
Wilson, Louis F
core +3 more sources
Spider venom administration impairs glioblastoma growth and modulates immune response in a non-clinical model. [PDF]
, 2020 Molecules from animal venoms are promising candidates for the development of new drugs. Previous in vitro studies have shown that the venom of the spider Phoneutria nigriventer (PnV) is a potential source of antineoplastic components with activity in ...
Barreto, Natália +12 more
core +1 more source
Spider neurotoxins targeting voltage-gated sodium channels [PDF]
, 2005 The voltage-gated sodium (Nav) channel is a target for a number of drugs, insecticides, and neurotoxins. These bind to at least seven identified neurotoxin binding sites and either block conductance or modulate sodium channel gating and/or kinetics.
Little, MJ, Nicholson, GM
core +1 more source
Revealing the Venomous Secrets of the Spider’s Web
Journal of Proteome Research, 2020 Orb-weaving spiders use a highly strong, sticky and elastic web to catch their prey. These web properties alone would be enough for the entrapment of prey; however, these spiders may be hiding venomous secrets in the web, which current research is revealing. Here, we provide strong proteotranscriptomic evidence for the presence of toxin/neurotoxin-like
Franciele Grego Esteves +11 more
openaire +5 more sources
Toxins, 2021 The spider family Sicariidae includes three genera, Hexophthalma, Sicarius and Loxosceles. The three genera share a common characteristic in their venoms: the presence of Sphingomyelinases D (SMase D).
Priscila Hess Lopes +4 more
doaj +1 more source
Spider Venoms: Biochemical Aspects [PDF]
American Zoologist, 1969 SYNOPSIS. The venoms of spiders are quite complex and contain an array of biologically active components. The majority of studies on the biochemical aspects of these venoms have utilized four species: Phoneutria fera, Lycosa erythrognatha, Atrax robustus , and Latrodectus mactans .
openaire +3 more sources
Insect-selective spider toxins targeting voltage-gated sodium channels [PDF]
, 2007 The voltage-gated sodium (Nav) channel is a target for a number of drugs, insecticides and neurotoxins. These bind to at least seven identified neurotoxin binding sites and either block conductance or modulate Nav channel gating.
Nicholson, GM
core +1 more source
Scientific Reports, 2022 Prey-specialised spiders are adapted to capture specific prey items, including dangerous prey. The venoms of specialists are often prey-specific and less complex than those of generalists, but their venom composition has not been studied in detail. Here,
Ondřej Michálek +5 more
doaj +1 more source
ArachnoServer 2.0, an updated online resource for spider toxin sequences and structures [PDF]
, 2011 ArachnoServer (www.arachnoserver.org) is a manually curated database providing information on the sequence, structure and biological activity of protein toxins from spider venoms.
Binford, G +8 more
core +1 more source